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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 14,526–14,550 of 27,380 studies, newest first · page 582 of 1096.

December 2017 25

  1. 2017-12-09

    MiR-124 acts as a target for Alzheimer's disease by regulating BACE1

    ⚠ Retracted — do not rely on it Risk genes beyond APOE Oncotarget

    Key finding: Beta-site Amyloid precursor protein Cleaving Enzyme 1 (BACE1) has been one of the prime therapeutic targets for AD. +3 more findings

    Scored 24 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  2. 2017-12-08

    Feasibility of Training and Delivering Compassionate Touch in Long-Term Care

    ✓ Peer-reviewed Health systems and care delivery Clinical gerontologist

    Key finding: Twenty-four staff members completed the survey and reported positive perspectives about the training, use of the program, and benefits for PWD and themselves. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2017-12-08

    Sleep and Cognition in Older Adults

    ✓ Peer-reviewed Risk factors Sleep medicine clinics

    Key finding: Increased age is associated with normative declines in both sleep and cognitive functioning. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2017-12-08

    Prebiotic Effect of Fructooligosaccharides from Morinda officinalis on Alzheimer's Disease in Rodent Models by Targeting the Microbiota-Gut-Brain Axis

    ✓ Peer-reviewed Disease mechanisms Frontiers in aging neuroscience

    Key finding: A previous study demonstrated that fructooligosaccharides from Morinda officinalis (OMO) exert effective memory improvements in AD-like animals, thereby considered as potential prebiotics; however, the underlying mechanism still remains enigma. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2017-12-08

    A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease

    ✓ Peer-reviewed Treatments Alzheimer's research & therapy

    Key finding: The study was stopped early for futility, but dose-dependent effects observed in exploratory analyses on select clinical and biomarker endpoints suggest that higher dosing with gantenerumab may be necessary to achieve clinical efficacy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2017-12-08

    The Wisconsin Registry for Alzheimer's Prevention: A review of findings and current directions

    ✓ Peer-reviewed Caregiving Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: In this cohort, PH of probable AD is associated with 46% apolipoprotein E ( APOE ) ε4 positivity, more than twice the rate of 22% among persons without PH. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2017-12-08

    Dementia with Lewy bodies and Parkinson's disease-dementia: current concepts and controversies

    ✓ Peer-reviewed Genetics Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: Intravitam PET and post-mortem studies revealed more pronounced cortical atrophy, elevated cortical and limbic Lewy pathologies (with APOE ε4), apart from higher prevalence of Alzheimer pathology in DLB than PDD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2017-12-07

    Evaluating Cognitive Reserve Through the Prism of Preclinical Alzheimer Disease

    ✓ Peer-reviewed Risk factors The Psychiatric clinics of North America

    Key finding: Current evidence shows that higher levels of CR are associated with a delay in the onset of symptoms of mild cognitive impairment and that there may be multiple pathways by which CR exerts its protective effects.

    Full summary, score breakdown and related studies → Original source

  9. 2017-12-07

    Obstructive sleep apnoea and Alzheimer's disease: In search of shared pathomechanisms

    ✓ Peer-reviewed Risk factors Neuroscience and biobehavioral reviews

    Key finding: Alzheimer's disease (AD) is a significant public health concern. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2017-12-07

    β-Sheet Structure within the Extracellular Domain of C99 Regulates Amyloidogenic Processing

    ✓ Peer-reviewed Biomarkers Scientific reports

    Key finding: Mutations that disrupt this structure result in a significant increase in Aβ production and, in specific cases, result in an increase in the amount of Aβ42 relative to Aβ40. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2017-12-07

    Aging, Obesity, and Inflammatory Age-Related Diseases

    ✓ Peer-reviewed Risk factors Frontiers in immunology

    Key finding: Immune cells of both the innate and the adaptive immune systems infiltrate the adipose tissue (AT) and during obesity induce inflammatory responses associated with metabolic switches and changes in phenotypes and function of immune cell subsets. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2017-12-07

    Generation of Structural MR Images from Amyloid PET: Application to MR-Less Quantification

    ✓ Peer-reviewed Biomarkers Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: Generated MR images from florbetapir PET showed signal patterns that were visually similar to the real MR. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2017-12-06

    Neurologic Changes and Depression

    ✓ Peer-reviewed Risk factors The Psychiatric clinics of North America

    Key finding: Research is then provided on neuropsychological changes associated with depression, discussing subjective cognitive impairment, mild cognitive impairment, and dementia profiles.

    Full summary, score breakdown and related studies → Original source

  14. 2017-12-06

    ApoE4 Accelerates Early Seeding of Amyloid Pathology

    ✓ Peer-reviewed Genetics Neuron

    Key finding: ApoE4, but not apoE3, significantly increased brain Aβ half-life measured by in vivo microdialysis. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2017-12-06

    Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity

    ✓ Peer-reviewed Disease mechanisms Nature

    Key finding: However, we know relatively little about the underlying molecular mechanisms or how to treat patients with Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2017-12-06

    Modifiable pathways in Alzheimer's disease: Mendelian randomisation analysis

    ✓ Peer-reviewed Prevention and risk BMJ (Clinical research ed.)

    Key finding: These results provide support that higher educational attainment is associated with a reduced risk of Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2017-12-06

    Feasibility and efficacy data from a ketogenic diet intervention in Alzheimer's disease

    ✓ Peer-reviewed Caregiving Alzheimer's & dementia (New York, N. Y.)

    Key finding: This pilot trial justifies KD studies in mild Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  18. 2017-12-05

    Augmenting cognitive training in older adults (The ACT Study): Design and Methods of a Phase III tDCS and cognitive training trial

    ✓ Peer-reviewed Prevention trials Contemporary clinical trials

    Key finding: The findings from this study have the potential to significantly enhance efforts to ameliorate cognitive aging and slow dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2017-12-05

    Sensation and Psychiatry: Linking Age-Related Hearing Loss to Late-Life Depression and Cognitive Decline

    ✓ Peer-reviewed Prevention and risk The American journal of psychiatry

    Key finding: Recent research has linked age-related hearing loss to impaired performance across cognitive domains and increased risk for dementia diagnosis. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2017-12-01

    "Tau immunotherapy: Hopes and hindrances"

    ✓ Peer-reviewed Drug development Human vaccines & immunotherapeutics

    Key finding: Recently, we have shown that phosphorylated tau at Thr231 in the cis conformation is a very early driver of neurodegeneration and cis mAb treatment efficiently restores brain structure and function in TBI models.

    Full summary, score breakdown and related studies → Original source

  21. 2017-12-01

    Environment and Neurodegenerative Diseases: An Update on miRNA Role

    ✓ Peer-reviewed Risk factors MicroRNA (Shariqah, United Arab Emirates)

    Key finding: A discussion with theoretical and possible future research directions is provided and it is clear that the need is not only of longitudinal population studies and of better knowledge of epigenetics markers but, especially, of environmental policy interventions based on the green economy. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2017-12-01

    Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Nature

    Key finding: These findings support the concept that inflammasome activation is connected to seeding and spreading of amyloid-β pathology in patients with Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  23. 2017-12-01

    Human longevity: 25 genetic loci associated in 389,166 UK biobank participants

    ✓ Peer-reviewed Genetics Aging

    Key finding: Of these, 4 were also associated with longest 10% survival (mothers age ≥90 years, fathers ≥87 years), with 2 additional associations including MC2R intronic variants (coding for the adrenocorticotropic hormone receptor). +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2017-12-01

    An economic model of advance care planning in Australia: a cost-effective way to respect patient choice

    ✓ Peer-reviewed End-of-life care BMC health services research

    Key finding: A nationwide ACP program in the primary care setting is a cost-effective or cost-saving intervention compared to usual care in a population at-risk of developing dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2017-12-01

    Benzodiazepines and Z-Drugs: An Updated Review of Major Adverse Outcomes Reported on in Epidemiologic Research

    ✓ Peer-reviewed Clinical safety Drugs in R&D

    Key finding: Various adverse events resulting from, or associated with, benzodiazepine and/or Z-drug use have been extensively reported on and discussed in great detail within the biomedical literature.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →