alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26889 of the 27780 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,001–23,025 of 27,780 studies, newest first · page 921 of 1112.

April 2007 17

  1. 2007-04-01

    Cerebrospinal fluid tau protein is increased in neurosyphilis: a discrimination from syphilis without nervous system involvement?

    ✓ Peer-reviewed Tau biomarkers Sexually transmitted diseases

    Key finding: The objective of this study was to investigate the levels of tau protein in neurosyphilis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2007-04-01

    TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis

    ✓ Peer-reviewed TREM2 and immune genetics PLoS medicine

    Key finding: In multiple sclerosis, inflammation can successfully be prevented, while promoting repair is still a major challenge. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2007-04-01

    Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: One environmental factor that is increasingly being recognized as contributing to brain aging is diet, which has evolved markedly over modern history. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2007-04-01

    Efficacy of cognitive rehabilitation in patients with mild cognitive impairment treated with cholinesterase inhibitors

    ✓ Peer-reviewed Mild cognitive impairment International journal of geriatric psychiatry

    Key finding: A long-term TNP in ChEIs-treated MCI subjects induces additional cognitive and mood benefits. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2007-04-01

    Accumulation of pathological tau species and memory loss in a conditional model of tauopathy

    ✓ Peer-reviewed Lewy body dementia The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Neurofibrillary tangles (NFTs) are a pathological hallmark of Alzheimer's disease and other tauopathies, but recent studies in a conditional mouse model of tauopathy (rTg4510) have suggested that NFT formation can be dissociated from memory loss and neurodegeneration. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2007-04-01

    Neuropsychiatric and behavioral aspects of trisomy 21

    ✓ Peer-reviewed Down syndrome and Alzheimer's Current psychiatry reports

    Key finding: The well-known cheerful and friendly demeanor often creates a personality stereotype, with parents and observers commenting on the positive attributes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2007-04-01

    Body mass index in midlife and risk of Alzheimer disease and vascular dementia

    ✓ Peer-reviewed How common it is Current Alzheimer research

    Key finding: Prior work has suggested that obesity and overweight as measured by body mass index (BMI) increases risk of dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2007-04-01

    The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort

    ✓ Peer-reviewed Disparities Archives of neurology

    Key finding: This study confirms the association between genetic variants in SORL1 and AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2007-04-01

    Brain structural alterations before mild cognitive impairment

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Structural brain changes in anatomic areas involved in higher cognitive processes precede clinical signs and symptoms in longitudinally followed normal subjects destined to develop mild cognitive impairment.

    Full summary, score breakdown and related studies → Original source

  10. 2007-04-01

    Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in dementia with Lewy bodies: a phase III, multicentre study

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: A mean value of 85.7% was achieved for overall diagnostic accuracy, 82.4% for positive predictive value, and 87.5% for negative predictive value. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2007-04-01

    Effect of galantamine on verbal repetition in AD: a secondary analysis of the VISTA trial

    ✓ Peer-reviewed Treatments Neurology

    Key finding: Reduction of verbal repetition was set as a treatment goal in 44% (n = 57) of randomized patients. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2007-04-01

    A 24-week randomized, controlled trial of memantine in patients with moderate-to-severe Alzheimer disease

    ✓ Peer-reviewed Treatments Alzheimer disease and associated disorders

    Key finding: Prospectively defined analyses failed to demonstrate a statistically significant benefit of memantine treatment compared with placebo on the Severe Impairment Battery (SIB) at week 24 end point, although a significant advantage was observed for memantine at weeks 12 and 18. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2007-04-01

    Quetiapine for agitation or psychosis in patients with dementia and parkinsonism

    ✓ Peer-reviewed Treatments Neurology

    Key finding: Quetiapine was well-tolerated and did not worsen parkinsonism. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2007-04-01

    Association of increased cortical soluble abeta42 levels with diffuse plaques after severe brain injury in humans

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: Selective increases in soluble Abeta(1-42) after TBI may predispose individuals with a brain injury to Alzheimer disease pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2007-04-01

    Systemic inflammation, infection, ApoE alleles, and Alzheimer disease: a position paper

    ✓ Peer-reviewed Genetics Current Alzheimer research

    Key finding: Blood levels of CRP and IL-6 are also associated with higher risk of Alzheimer disease and cognitive decline during aging.

    Full summary, score breakdown and related studies → Original source

  16. 2007-04-01

    Course of cerebral amyloid angiopathy-related inflammation

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Baseline MRI scans were characterized by asymmetric T2-hyperintense lesions extending to the subcortical white matter and occasionally the overlying gray matter, with signal properties suggesting vasogenic edema. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2007-04-01

    Relation of diabetes to mild cognitive impairment

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: Diabetes is related to a higher risk of amnestic MCI in a population with a high prevalence of this disorder. +4 more findings

    Full summary, score breakdown and related studies → Original source

March 2007 8

  1. 2007-03-29

    Curcumin labels amyloid pathology in vivo , disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model

    ✓ Peer-reviewed Vascular contributions Journal of Neurochemistry

    Key finding: Curcumin also led to a limited, but significant reversal of structural changes in dystrophic dendrites, including abnormal curvature and dystrophy size. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2007-03-29

    Diagnostic accuracy of ELISA and xMAP technology for analysis of amyloid beta(42) and tau proteins

    ✓ Peer-reviewed Tau biomarkers Clinical chemistry

    Key finding: Cerebrospinal fluid (CSF) concentrations of amyloid beta(42) (Abeta(42)) peptides and tau proteins may serve as biomarkers for Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2007-03-28

    The associations among hippocampal volume, cortisol reactivity, and memory performance in healthy young men

    ✓ Peer-reviewed Hippocampus size on brain scans Psychiatry research

    Key finding: The results show that larger hippocampal volume was associated with a significantly stronger cortisol increase in response to the TSST and a significantly greater CRA. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2007-03-27

    Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia

    ✓ Peer-reviewed Hippocampus size on brain scans Molecular psychiatry

    Key finding: Here, we provide evidence that genetic variants of the genes encoding PACAP and its receptor, PAC1, are associated with schizophrenia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2007-03-26

    Forensic issues in Down syndrome fatalities

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of forensic and legal medicine

    Key finding: Down syndrome, or trisomy 21, is the most common chromosomal abnormality associated with intellectual impairment.

    Full summary, score breakdown and related studies → Original source

  6. 2007-03-23

    Subjective memory complaints, education, and risk of Alzheimer's disease

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Although memory complaints are associated with an increased risk of Alzheimer's disease in persons with cognitive impairment as well as in persons with normal cognition, they are commonly considered of less importance than objective cognitive measures. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2007-03-19

    Abnormal retinal thickness in patients with mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Neuroscience letters

    Key finding: The results show that RNFL thickness is statistically reduced in patients with MCI, mild AD or moderate to severe AD compared to controls. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2007-03-13

    Serotonin transporter polymorphism, memory and hippocampal volume in the elderly: association and interaction with cortisol

    ✓ Peer-reviewed Hippocampus size on brain scans Molecular psychiatry

    Key finding: The 5-HTT s allele was associated with both significantly lower delayed recall and higher waking cortisol levels. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →