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54/100

✓ Peer-reviewed alzhub usefulness score 54 out of 100. Long-term cohort studies

Topic: Risk, prevention and care in population studies

Background Previous studies reported a higher risk of cognitive decline and dementia amongst individuals with impaired lung function. However, many did not adjust for important confounders or did not include women and non-whites. Methods We studied 10,975 men and women aged 47-70 years (23% African-Americans) enrolled in the Atherosclerosis Risk in Communities Study.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Pathan, S. S., Gottesman, R. F., Mosley, T. H., Knopman, D. S., Sharrett, A. R., & Alonso, A. (2011). Association of lung function with cognitive decline and dementia: the Atherosclerosis Risk in Communities (ARIC) Study. European journal of neurology. https://doi.org/10.1111/j.1468-1331.2010.03340.x

Vancouver

Pathan SS, Gottesman RF, Mosley TH, Knopman DS, Sharrett AR, Alonso A. Association of lung function with cognitive decline and dementia: the Atherosclerosis Risk in Communities (ARIC) Study. European journal of neurology. 2011. doi:10.1111/j.1468-1331.2010.03340.x. PMID: 21244584.

BibTeX

@article{pathan2011-21244584,
  author  = {Pathan, S. S. and Gottesman, R. F. and Mosley, T. H. and Knopman, D. S. and Sharrett, A. R. and Alonso, A.},
  title   = {{Association of lung function with cognitive decline and dementia: the Atherosclerosis Risk in Communities (ARIC) Study}},
  journal = {European journal of neurology},
  year    = {2011},
  doi     = {10.1111/j.1468-1331.2010.03340.x},
  pmid    = {21244584},
  url     = {https://doi.org/10.1111/j.1468-1331.2010.03340.x}
}

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Key findings

However, many did not adjust for important confounders or did not include women and non-whites.
Methods We studied 10,975 men and women aged 47-70 years (23% African-Americans) enrolled in the Atherosclerosis Risk in Communities Study.
Pulmonary function tests and a cognitive assessment, including the Delayed Word Recall, the Digit Symbol Substitution, and the World Fluency Tests, were carried out in 1990-1992.
Repeated cognitive assessments were performed in 1996-1998 for the entire cohort, and in 1993-1995, and 2004-2006 in 904 eligible individuals.

Why it matters

This study looked at whether impaired lung function is associated with cognitive decline and dementia in a large cohort. It examines a possible risk factor but does not test any treatment, cure, or prevention.

Study details

Participants10,975
Evidence strengthModerate

How this study scored 54/100

Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (European journal of neurology)
Journal's citation record	2 / 4	European Journal of Neurology: journal h-index 181 (OpenAlex, 2026-10-29)
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	3 / 5	Rated “moderate” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	1 / 5	2011 — within 20 year(s) of the newest study here
Sample size	4 / 4	10,975 participants
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	5 / 7	Cited 116 times (OpenAlex, 2026-10-10)
Citations per year	2 / 5	6.8 citations a year over 17 year(s) since 2011
Impact for its field and year	3 / 6	Cited 3.2× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	2 / 6	Cited by 4 other studies in this library
Still being cited	2 / 4	Cited 26 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	4 / 4	Last-listed author Álvaro Alonso: h-index 115 (OpenAlex, whole career)
Institution's track record	2 / 3	Johns Hopkins University: institution h-index 2,306 (OpenAlex)
Multi-centre collaboration	2 / 3	OpenAlex lists 6 institution(s) in 1 country
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 21244584)
Free to read	0 / 2	Behind a paywall — scores zero
Total	54 / 100	—

What each of these 20 components measures, and what this score is not →

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