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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,801–19,825 of 27,380 studies, newest first · page 793 of 1096.

November 2011 25

  1. 2011-11-30

    Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels

    ✓ Peer-reviewed Genetics The Journal of biological chemistry

    Key finding: Previously, we demonstrated that intracellular degradation of β-amyloid (Aβ) peptides by microglia is dramatically enhanced in the presence of apoE. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2011-11-29

    Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia

    ✓ Peer-reviewed Down syndrome and Alzheimer's Current gerontology and geriatrics research

    Key finding: In addition, considering the role of mitochondrial dysfunction in neurodegenerative phenomena, results demonstrating the involvement of impaired mitochondria in DS pathology could contribute a direct link between normal aging and development of AD-like dementia in DS patients.

    Full summary, score breakdown and related studies → Original source

  3. 2011-11-28

    Spines, plasticity, and cognition in Alzheimer's model mice

    ✓ Peer-reviewed Disease mechanisms Neural plasticity

    Key finding: Transgenic mice have been developed based on rare familial forms of AD and frontotemporal dementia, allowing investigators to test in detail the structural, functional, and behavioral consequences of AD-associated pathology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2011-11-28

    Amyloid β: linking synaptic plasticity failure to memory disruption in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Journal of neurochemistry

    Key finding: Mounting evidence suggests that amyloid beta-induced impairments in synaptic plasticity that is accompanied by cognitive decline and dementia represent key pathogenic steps of Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  5. 2011-11-28

    Evaluation of a Japanese version of the Mini-Mental State Examination in elderly persons

    ✓ Peer-reviewed Cognitive tests and assessment Geriatrics & gerontology international

    Key finding: This study aimed to examine the validity and item-response characteristics of the Mini-Mental State Examination (MMSE), which is used for assessing cognitive function, in Japanese older adults. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2011-11-28

    The role of metallobiology and amyloid-β peptides in Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neurochemistry

    Key finding: Why age triggers the disease is unclear but an emerging theme is the inability for a cell to efficiently maintain many key processes such as energy production, repair, and regenerative mechanisms. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2011-11-24

    Evidence for Elevated Cerebrospinal Fluid ERK1/2 Levels in Alzheimer Dementia

    ✓ Peer-reviewed Tau biomarkers International journal of Alzheimer's disease

    Key finding: The results were evaluated in relation to total Tau (tTau), phosphorylated Tau (pTau), and beta-amyloid 42 peptide (Aβ42). +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2011-11-23

    Alzheimer's disease: pathological mechanisms and the beneficial role of melatonin

    ✓ Peer-reviewed Inflammation and the immune system Journal of pineal research

    Key finding: This review summarizes these diverse aspects of this form of dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2011-11-23

    Genome-wide association study of vascular dementia

    ✓ Peer-reviewed Long-term cohort studies Stroke

    Key finding: Most studies investigating the genetics of dementia have focused on Alzheimer disease, but little is known about the genetics of vascular dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2011-11-23

    Chronic kidney disease, cognitive decline, and incident dementia: the 3C Study

    ✓ Peer-reviewed Cognitive tests and assessment Neurology

    Key finding: This study is based on a population-based cohort of 7,839 subjects over 65 years with 7 years of follow-up. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2011-11-22

    The future of Alzheimer's disease: the next 10 years

    ✓ Peer-reviewed Caregiving Progress in neurobiology

    Key finding: The strong age-related incidence, the recent failure and complete lack of disease-modifying or preventive therapy that may delay onset or substantially affect the pathophysiology of AD, result in an enormous burden posed both on individuals, their families and care givers, and the societies at large, and these call for urgent concerted worldwide measures.

    Full summary, score breakdown and related studies → Original source

  12. 2011-11-20

    National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach

    ✓ Peer-reviewed Lewy body dementia Acta neuropathologica

    Key finding: Recommendations also are made for the minimum sampling of brain, preferred staining methods with acceptable alternatives, reporting of results, and clinico-pathologic correlations.

    Full summary, score breakdown and related studies → Original source

  13. 2011-11-17

    Impairments of speech fluency in Lewy body spectrum disorder

    ✓ Peer-reviewed Digital health tools Brain and language

    Key finding: Both demented and non-demented PD patients exhibited reduced speech fluency, characterized by reduced overall speech rate and long pauses between sentences. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2011-11-16

    Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Our voxel-wise results indicated that ASL-MRI provides largely overlapping information with FDG-PET. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2011-11-15

    Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease

    ✓ Peer-reviewed Treatments Journal of medicinal chemistry

    Key finding: Overall, the results suggest that the new compounds are promising multitarget drug candidates with potential impact for Alzheimer's disease therapy.

    Full summary, score breakdown and related studies → Original source

  16. 2011-11-15

    Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72

    ✓ Peer-reviewed Brain tissue and pathology Acta neuropathologica

    Key finding: Strong evidence supporting this is the existence of kindreds with family members affected by FTD, ALS or mixed features of FTD and ALS, referred to as FTD-MND. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2011-11-12

    Effects of acute and chronic administration of GIP analogues on cognition, synaptic plasticity and neurogenesis in mice

    ✓ Peer-reviewed Drug development European journal of pharmacology

    Key finding: We found that after acute injection, D-Ala2GIP had few effects on general behaviour in the open field at any dose tested (2.5, 25, 100, or 250 nmol/kg i.p.). +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2011-11-12

    (Val⁸) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains

    ✓ Peer-reviewed Tau biomarkers European journal of pharmacology

    Key finding: In the present study, (Val(8))GLP-1 was used to prevent impairments in memory formation, tau hyperphosphorylation and ultra-structural changes induced by streptozotocin intracerebroventricular (i.c.v.) injection. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2011-11-12

    PET amyloid-beta imaging in preclinical Alzheimer's disease

    ✓ Peer-reviewed Prevention and risk Biochimica et biophysica acta

    Key finding: New therapies which focus on prevention or delay of the onset or cognitive symptoms are needed. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2011-11-10

    Zinc and human health: an update

    ✓ Peer-reviewed Genetics Archives of toxicology

    Key finding: Zinc has critical effect in homeostasis, in immune function, in oxidative stress, in apoptosis, and in aging, and significant disorders of great public health interest are associated with zinc deficiency. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2011-11-10

    Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy

    ✓ Peer-reviewed Mild cognitive impairment Metabolic brain disease

    Key finding: Five out of 11 patients with NASH, without liver cirrhosis, showed cognitive impairment associated with hyperammonemia and inflammation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2011-11-09

    SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Soluble amyloid β (Aβ) oligomers cause cognitive impairment and synaptic dysfunction in Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2011-11-09

    The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort

    ✓ Peer-reviewed Brain scans and imaging The American journal of clinical nutrition

    Key finding: Loss of cholinergic neurons is associated with impaired cognitive function, particularly memory loss and Alzheimer disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2011-11-08

    CSF biomarkers in different phenotypes of Parkinson disease

    ✓ Peer-reviewed Tau biomarkers Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: In both NT-PD and AD patients total tau levels and the cortex tau/Aβ-42 were significantly increased compared to both TD-PD patients and controls (p < 0.01). +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2011-11-07

    Longitudinal structure-function correlates in elderly reveal MTL dysfunction with cognitive decline

    ✓ Peer-reviewed Hippocampus size on brain scans Cerebral cortex (New York, N.Y. : 1991)

    Key finding: Evidence from functional and structural neuroimaging has revealed that hippocampal volume and activation patterns in the medial temporal lobe (MTL) may predict cognitive performance in old age. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →