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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 25,951–25,975 of 27,380 studies, newest first · page 1039 of 1096.

June 1998 5

  1. 1998-06-01

    Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

    ✓ Peer-reviewed Lewy body dementia Nature

    Key finding: Previous studies have mapped the FTDP-17 locus to a 2-centimorgan region on chromosome 17q21.11; the tau gene also lies within this region. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1998-06-01

    Tau is a candidate gene for chromosome 17 frontotemporal dementia

    ✓ Peer-reviewed Digital health tools Annals of neurology

    Key finding: Frontotemporal dementia with parkinsonism, chromosome 17 type (FTDP-17), a recently defined disease entity, is clinically characterized by personality changes sometimes associated with psychosis, hyperorality, and diminished speech output, disturbed executive function and nonfluent aphasia, bradykinesia, and rigidity. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1998-06-01

    Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study

    ✓ Peer-reviewed How common it is Lancet (London, England)

    Key finding: During mean follow-up of 2.1 (range 1.5-3.4) years, 146 incident cases of dementia were detected, of which 105 were Alzheimer's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1998-06-01

    The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): preliminary clinical validity

    ✓ Peer-reviewed Getting a diagnosis Journal of clinical and experimental neuropsychology

    Key finding: The current study reports preliminary clinical validity results with the RBANS, comparing very mildly demented patients with a diagnosis of probable Alzheimer's disease (n = 20) to patients with Huntington's disease (n = 20) and normal controls (n = 40). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1998-06-01

    A genome survey for novel Alzheimer disease risk loci: results at 10-cM resolution

    ✓ Peer-reviewed Genetics Genomics

    Key finding: Allelic associations with AD were observed for 6 of the 391 SSTRPs in the CHLC Human Screening Set/Weber Version 6 (Research Genetics, Inc., Huntsville, AL): D1S518, D1S547, D10S1423, D12S1045, D19S178, and DXS1047. +4 more findings

    Full summary, score breakdown and related studies → Original source

May 1998 15

  1. 1998-05-26

    Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons

    ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences

    The amyloid precursor protein (APP) plays a crucial role in the pathogenesis of Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  2. 1998-05-26

    Diffusible, nonfibrillar ligands derived from Aβ 1–42 are potent central nervous system neurotoxins

    ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences

    Abeta1-42 is a self-associating peptide whose neurotoxic derivatives are thought to play a role in Alzheimer's pathogenesis.

    Full summary, score breakdown and related studies → Original source

  3. 1998-05-01

    Energy Thresholds in Brain Mitochondria

    ✓ Peer-reviewed Disease mechanisms Journal of Biological Chemistry

    Key finding: These results suggest that, in mitochondria of synaptic origin, complex I activity has a major control of oxidative phosphorylation, such that when a threshold of 25% inhibition is exceeded, energy metabolism is severely impaired, resulting in a reduced synthesis of ATP. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1998-05-01

    The Impact of Gender and Estrogen on Striatal Dopaminergic Neurotoxicity

    ✓ Peer-reviewed Biomarkers Annals of the New York Academy of Sciences

    Key finding: Estrogen replacement reduced the DA, dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) depletions as well as the glial fibrillary acidic protein (GFAP) elevation induced by MPTP, which indicates that estrogen has neuroprotective properties in this model of striatal dopaminergic neurotoxicity. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 1998-05-01

    Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins

    ✓ Peer-reviewed Biomarkers The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: The epsilon4 allele of apolipoprotein E (apoE) is associated with increased risk for Alzheimer's disease (AD) and poor outcome after brain injury. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1998-05-01

    Recurrent seizures may cause hippocampal damage in temporal lobe epilepsy

    ✓ Peer-reviewed Hippocampus size on brain scans Neurology

    Key finding: In patients with cryptogenic epilepsy, recurrent seizures may cause damage to the hippocampus throughout the lifetime of the patient.

    Full summary, score breakdown and related studies → Original source

  7. 1998-05-01

    Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging: a meta-analytic study

    ✓ Peer-reviewed Hippocampus size on brain scans Archives of general psychiatry

    Key finding: Schizophrenia is associated with a bilateral volumetric reduction of the hippocampus and probably of the amygdala as well. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1998-05-01

    Cortisol levels during human aging predict hippocampal atrophy and memory deficits

    ✓ Peer-reviewed Hippocampus size on brain scans Nature neuroscience

    Key finding: Here we demonstrate that aged humans with significant prolonged cortisol elevations showed reduced hippocampal volume and deficits in hippocampus-dependent memory tasks compared to normal-cortisol controls.

    Full summary, score breakdown and related studies → Original source

  9. 1998-05-01

    CLOX: an executive clock drawing task

    ✓ Peer-reviewed Cognitive tests and assessment Journal of neurology, neurosurgery, and psychiatry

    Key finding: Subjects 90 elderly subjects were studied (45 elderly and well persons from the independent living apartments of a continuing care retirement community and 45 patients with probable Alzheimer's disease). +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1998-05-01

    alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

    ✓ Peer-reviewed Lewy body dementia Proceedings of the National Academy of Sciences of the United States of America

    Key finding: The morphologies of the 5- to 10-nm filaments and their staining characteristics suggest that extended alpha-synuclein molecules run parallel to the filament axis and that the filaments are polar structures. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 1998-05-01

    Apolipoprotein E epsilon 4 alleles and meiotic origin of non-disjunction in Down syndrome children and in their corresponding fathers and mothers

    ✓ Peer-reviewed Down syndrome and Alzheimer's Neuroscience letters

    Key finding: An increased risk of Alzheimer disease (AD) has been reported in young mothers of Down syndrome (DS) probands. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 1998-05-01

    Cognitive test performance among nondemented elderly African Americans and whites

    ✓ Peer-reviewed Disparities Neurology

    Key finding: African American elders obtained significantly lower scores on measures of verbal and nonverbal learning and memory, abstract reasoning, language, and visuospatial skill than whites. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 1998-05-01

    Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease

    ✓ Peer-reviewed Caregiving Neurology

    Key finding: Metrifonate was safe and well-tolerated.

    Full summary, score breakdown and related studies → Original source

  14. 1998-05-01

    Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study. Donepezil Study Group

    ✓ Peer-reviewed Treatments Archives of internal medicine

    Key finding: The use of donepezil produced statistically significant improvements in ADAS-cog, CIBIC plus, and Mini-Mental State Examination scores, relative to placebo. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 1998-05-01

    Distribution of reducible 4-hydroxynonenal adduct immunoreactivity in Alzheimer disease is associated with APOE genotype

    ✓ Peer-reviewed Genetics Journal of neuropathology and experimental neurology

    Key finding: Also associated with AD is increased lipid peroxidation in the regions of the brain most damaged by disease. 4-hydroxynonenal (HNE), the most potent neurotoxic product of lipid peroxidation, is thought to be deleterious to cells through reactions with protein nucleophiles. +4 more findings

    Full summary, score breakdown and related studies → Original source

April 1998 5

  1. 1998-04-01

    Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: a regional quantitative analysis

    ✓ Peer-reviewed Down syndrome and Alzheimer's Experimental neurology

    Key finding: The presence of the neuropathological alterations of Alzheimer's disease (AD) in essentially all older Down syndrome (DS) patients suggests that the examination of younger DS patients may clarify the early pathological progression of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1998-04-01

    The accuracy of substituted judgments in patients with terminal diagnoses

    ✓ Peer-reviewed End-of-life care Annals of internal medicine

    Key finding: The accuracy of substituted judgments is associated with multiple clinically apparent patient and surrogate factors. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1998-04-01

    Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

    ✓ Peer-reviewed Brain tissue and pathology The Journal of biological chemistry

    Key finding: We hypothesized that alpha-synuclein should associate with phospholipid bilayers and that this lipid association should stabilize an alpha-helical secondary structure in the protein. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1998-04-01

    Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies

    ✓ Peer-reviewed Brain tissue and pathology The American journal of pathology

    Key finding: Recently, a point mutation in the gene encoding the presynaptic alpha-synuclein protein was identified in some autosomal-dominantly inherited familial PD pedigrees, and light microscopic studies demonstrated alpha-synuclein immunoreactivity in LBs of sporadic PD and DLB. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1998-04-01

    Determinants of carer stress in Alzheimer's disease

    ✓ Peer-reviewed Risk factors International journal of geriatric psychiatry

    Key finding: The findings confirm that the non-cognitive features of Alzheimer's disease are stressful for carers and indicate specific relationships between mood-related and behavioural signs of depression, walking and sleep disruptions and hallucinations in patients and adverse carer outcomes. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →