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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,226–18,250 of 27,380 studies, newest first · page 730 of 1096.

December 2013 25

  1. 2013-12-18

    Tools and talk: an evolutionary perspective on the functional deficits associated with amyotrophic lateral sclerosis

    ✓ Peer-reviewed Digital health tools Muscle & nerve

    Key finding: We discuss how hand-arm function, locomotion, brainstem function (involving vocalization/speech, swallowing and breathing), and cognitive impairment share complex, interdependent evolutionary adaptations that can be traced back several million years. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2013-12-18

    Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: Over a median follow-up of 5.1 years, 153 of 534 participants (28.7%) with prevalent or incident MCI progressed to dementia (71.3 per 1,000 person-years). +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2013-12-18

    Physical exercise and cognitive performance in the elderly: current perspectives

    ✓ Peer-reviewed Prevention and risk Clinical interventions in aging

    Key finding: The results of observational studies support a dose-dependent neuroprotective relationship between physical exercise and cognitive performance in older adults.

    Full summary, score breakdown and related studies → Original source

  4. 2013-12-18

    Practical utility of amyloid and FDG-PET in an academic dementia center

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Concordance between scan results and baseline diagnosis was high (PiB 84%, FDG 82%). +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2013-12-17

    Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimer's disease transgenic mice

    ✓ Peer-reviewed Inflammation and the immune system Aging cell

    Key finding: It is the only one of the top ten causes of death in the USA for which prevention strategies have not been developed. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2013-12-16

    Cornell scale for depression in dementia: study of residents in a northern thai long-term care home

    ✓ Peer-reviewed Health systems and care delivery Psychiatry investigation

    Key finding: ROC analysis revealed a better score for those areas found under the curve for the CSDD-as against the DSM-IV criteria (0.96). +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2013-12-16

    Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease

    ✓ Peer-reviewed Drug development Free radical biology & medicine

    Key finding: In this study we used 12-month-old SAMP8 mice, an AD model, to examine the effects GSK-3β may cause regarding the cognitive impairment and oxidative stress associated with AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2013-12-16

    TREM2 and the neuroimmunology of Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Biochemical pharmacology

    Key finding: The ɛ4 allele of Apolipoprotein E(ApoEɛ4) was the only known major risk factor for late onset AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2013-12-13

    Puerarin: a review of pharmacological effects

    ✓ Peer-reviewed Prevention and risk Phytotherapy research : PTR

    Key finding: It is available in common foods and is used in alternative medicine. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2013-12-12

    Cognitive decline, dietary factors and gut-brain interactions

    ✓ Peer-reviewed Prevention trials Mechanisms of ageing and development

    Key finding: Epidemiological evidence supports the hypothesis that modifiable lifestyle-related factors are associated with cognitive decline, opening new avenues for prevention.

    Full summary, score breakdown and related studies → Original source

  11. 2013-12-11

    Age at surgical menopause influences cognitive decline and Alzheimer pathology in older women

    ✓ Peer-reviewed Prevention and risk Neurology

    Key finding: Early age at surgical menopause was associated with cognitive decline and AD neuropathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2013-12-11

    Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

    ✓ Peer-reviewed Genetics Nature

    Key finding: PLD3 is highly expressed in brain regions that are vulnerable to Alzheimer's disease pathology, including hippocampus and cortex, and is expressed at significantly lower levels in neurons from Alzheimer's disease brains compared to control brains. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2013-12-11

    Disparities in deep brain stimulation surgery among insured elders with Parkinson disease

    ✓ Peer-reviewed Disparities Neurology

    Key finding: Among elderly Medicare beneficiaries with PD, race, sex, and neighborhood SES are strong independent predictors of DBS receipt. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2013-12-10

    Liposomes bi-functionalized with phosphatidic acid and an ApoE-derived peptide affect Aβ aggregation features and cross the blood-brain-barrier: implications for therapy of Alzheimer disease

    ✓ Peer-reviewed Genetics Nanomedicine : nanotechnology, biology, and medicine

    Key finding: Surface plasmon resonance showed that bi-functionalized liposomes strongly bind Aβ (kD=0.6 μM), while Thioflavin-T and SDS-PAGE/WB assays show that liposomes inhibit peptide aggregation (70% inhibition after 72 h) and trigger the disaggregation of preformed aggregates (60% decrease after 120 h incubation). +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2013-12-09

    Criterion and convergent validity of the Montreal cognitive assessment with screening and standardized neuropsychological testing

    ✓ Peer-reviewed Cognitive tests and assessment Journal of the American Geriatrics Society

    Key finding: Cross-sectional observational study. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2013-12-08

    Identification of a unique TGF-β–dependent molecular and functional signature in microglia

    ✓ Peer-reviewed Inflammation and the immune system Nature Neuroscience

    Key finding: Of the 239 genes, 106 were enriched in microglia as compared with astrocytes, oligodendrocytes and neurons. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2013-12-08

    Both Targeted Mass Spectrometry and Flow Sorting Analysis Methods Detected the Decreased Serum Apolipoprotein E Level in Alzheimer's Disease Patients

    ✓ Peer-reviewed Risk factors Molecular & Cellular Proteomics

    Key finding: Apolipoprotein E (ApoE) polymorphism has been appreciated as a valuable predictor of Alzheimer disease (AD), and the associated ε4 allele has been recognized as an indicator of susceptibility to this disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2013-12-06

    Place of death and end-of-life transitions experienced by very old people with differing cognitive status: retrospective analysis of a prospective population-based cohort aged 85 and over

    ✓ Peer-reviewed End-of-life care Palliative medicine

    Key finding: Most very old community-dwelling individuals, especially the severely cognitively impaired, died away from home. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2013-12-04

    Right hemisphere role in cognitive reserve

    ✓ Peer-reviewed Digital health tools Neurobiology of aging

    Key finding: High levels of education, occupational complexity, and/or premorbid intelligence are associated with lower levels of cognitive impairment than would be expected from a given brain pathology.

    Full summary, score breakdown and related studies → Original source

  20. 2013-12-04

    Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain

    ✓ Peer-reviewed Genetics Neurobiology of aging

    Key finding: Whereas 5mC is generally associated with the inhibition of gene expression, 5hmC has been associated with increased gene expression and is involved in cellular processes such as differentiation, development, and aging. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2013-12-02

    Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: Triggering receptor expressed on myeloid cells 2 (TREM2) is a newly identified risk gene for AD, which regulates inflammatory process in peripheral tissues via modulating the release of inflammatory cytokines. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2013-12 month only

    Lysosome and calcium dysregulation in Alzheimer's disease: partners in crime

    ✓ Peer-reviewed Risk genes beyond APOE Biochemical Society transactions

    Key finding: Beyond the effects of PS1 mutations on proteolytic functions of the γ-secretase complex, mutant or deficient PS1 disrupts lysosomal function and Ca2+ homoeostasis, both of which are considered strong pathogenic factors in FAD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2013-12-01

    Deaths: leading causes for 2010

    ✓ Peer-reviewed Disparities National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System

    Key finding: In 2010, the 10 leading causes of death were, in rank order: Diseases of heart; Malignant neoplasms; Chronic lower respiratory diseases; Cerebrovascular diseases; Accidents (unintentional injuries); Alzheimer's disease; Diabetes mellitus; Nephritis, nephrotic syndrome and nephrosis; Influenza and pneumonia; and Intentional self-harm (suicide).

    Full summary, score breakdown and related studies → Original source

  24. 2013-12-01

    Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β-amyloid

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: CSF and amyloid PET measurements of Aβ were consistent in the majority of subjects in the cross-sectional and longitudinal populations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2013-12-01

    Self-reported sleep and β-amyloid deposition in community-dwelling older adults

    ✓ Peer-reviewed Brain scans and imaging JAMA neurology

    Key finding: Among community-dwelling older adults, reports of shorter sleep duration and poorer sleep quality are associated with greater Aβ burden. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →