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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,026–18,050 of 27,380 studies, newest first · page 722 of 1096.

February 2014 25

  1. 2014-02-25

    Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview

    ✓ Peer-reviewed Mild cognitive impairment Molecular neurobiology

    Key finding: Several cytokines are evidently regulated in (neuro-) inflammatory processes associated with neurodegenerative disorders. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2014-02-25

    Asymmetry and heterogeneity of Alzheimer's and frontotemporal pathology in primary progressive aphasia

    ✓ Peer-reviewed Genetics Brain : a journal of neurology

    Key finding: The most common and distinctive feature for all pathologies associated with primary progressive aphasia was the asymmetric prominence of atrophy, neuronal loss, and disease-specific proteinopathy in the language-dominant (mostly left) hemisphere. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2014-02-24

    Research on Multiple Chronic Conditions

    ✓ Peer-reviewed Risk factors Medical Care

    Key finding: This issue of Medical Care includes a theoretical framework for conducting research on MCC, a review of existing MCC research methods and methodological gaps to be addressed, and the results of several research studies addressing MCC. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2014-02-24

    Quantification of tau in cerebrospinal fluid by immunoaffinity enrichment and tandem mass spectrometry

    ✓ Peer-reviewed Tau biomarkers Clinical chemistry

    Key finding: Cerebrospinal fluid (CSF) tau is a common biomarker for Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2014-02-24

    Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans

    ✓ Peer-reviewed Prevention and risk Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Age-related MS and diabetes are also causally associated with suppressed SIRT1 partly due to oxidant glycotoxins [advanced glycation end products (AGEs)]. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2014-02-24

    APOE ε4 and the risk for Alzheimer disease and cognitive decline in African Americans and Yoruba

    ✓ Peer-reviewed Genetics International psychogeriatrics

    Key finding: The reasons for these differences remain unclear.

    Full summary, score breakdown and related studies → Original source

  7. 2014-02-23

    Functional brain connectivity using fMRI in aging and Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Neuropsychology review

    Key finding: Overall, connectivity and network integrity appear to decrease in healthy aging, but this decrease is accelerated in AD, with specific systems hit hardest, such as the default mode network (DMN).

    Full summary, score breakdown and related studies → Original source

  8. 2014-02-22

    Delirium superimposed on dementia strongly predicts worse outcomes in older rehabilitation inpatients

    ✓ Peer-reviewed Clinical safety Journal of the American Medical Directors Association

    Key finding: DSD is a strong predictor of functional dependence, institutionalization, and mortality in older patients admitted to a rehabilitation setting, suggesting that strategies to detect DSD routinely in practice should be developed and DSD should be included in prognostic models of health care. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2014-02-20

    Mutational analysis in early-onset familial Alzheimer's disease in Mainland China

    ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of aging

    Key finding: Subsequently, a hexanucleotide repeat expansion in C9orf72 was detected in all patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2014-02-20

    Patterns of cognitive function in aging: the Rotterdam Study

    ✓ Peer-reviewed Long-term cohort studies European journal of epidemiology

    Key finding: In more than 3,000 non-demented persons, aged 45-99 years, from the population-based Rotterdam Study we studied cross-sectional age effects on cognitive function across various domains. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2014-02-20

    Subjective caregiver burden: validity of the 10-item short version of the Burden Scale for Family Caregivers BSFC-s

    ✓ Peer-reviewed Caregiving BMC geriatrics

    Key finding: All hypotheses that referred to the construct validity were supported. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2014-02-20

    Olfactory bulb involvement in neurodegenerative diseases

    ✓ Peer-reviewed Getting a diagnosis Acta neuropathologica

    Key finding: The severity of olfactory bulb HPτ, Aβ, and αSyn pathology correlated and increased significantly (P < 0.001) with increasing neuritic Braak stages, Thal Aβ phases, and cerebral Lewy body pathology, respectively.

    Full summary, score breakdown and related studies → Original source

  13. 2014-02-19

    Chronic kidney disease is associated with dementia independent of cerebral small-vessel disease

    ✓ Peer-reviewed Genetics Neurology

    Key finding: CKD is independently related to the risk of all-cause dementia in patients with vascular risk factors. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2014-02-18

    A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly

    ✓ Peer-reviewed Risk genes beyond APOE Molecular psychiatry

    Key finding: Although we did not observe any genome-wide significant locus, we identified 18 suggestive loci (P<1 × 10(-)(5)). +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2014-02-18

    C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

    ✓ Peer-reviewed Lewy body dementia Human molecular genetics

    Key finding: Immunohistochemistry of C9ORF72 ALS patient motor neurons revealed increased colocalization between C9ORF72 and Rab7 and Rab11 compared with controls, suggesting possible dysregulation of trafficking in patients bearing the C9ORF72 repeat expansion.

    Full summary, score breakdown and related studies → Original source

  16. 2014-02-18

    Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys

    ✓ Peer-reviewed Lewy body dementia Annals of neurology

    Key finding: α-Synuclein species contained in PD-derived LB are pathogenic and have the capacity to initiate a PD-like pathological process, including intracellular and presynaptic accumulations of pathological α-synuclein in different brain areas and slowly progressive axon-initiated dopaminergic nigrostriatal neurodegeneration. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2014-02-16

    What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus

    ✓ Peer-reviewed Brain scans and imaging Progress in neurobiology

    Key finding: We suggest that regions characterized by a high degree of life-long plasticity are vulnerable to detrimental effects of normal aging, and that this age-vulnerability renders them more susceptible to additional, pathological AD-related changes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2014-02-15

    Sleep deprivation impairs memory, tau metabolism, and synaptic integrity of a mouse model of Alzheimer's disease with plaques and tangles

    ✓ Peer-reviewed Biomarkers Neurobiology of aging

    Key finding: Compared with controls, behavioral assessment showed that SD-treated mice had a significant decline in their learning and memory. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2014-02-14

    A phase 2 trial of the GSK‐3 inhibitor tideglusib in progressive supranuclear palsy

    ✓ Peer-reviewed Clinical safety Movement Disorders

    Key finding: No significant differences were detected in the primary or secondary endpoints at week 52 between placebo and either dose of tideglusib.

    Full summary, score breakdown and related studies → Original source

  20. 2014-02-14

    Comparing manual and automatic segmentation of hippocampal volumes: reliability and validity issues in younger and older brains

    ✓ Peer-reviewed Hippocampus size on brain scans Human brain mapping

    Key finding: With FreeSurfer, correlations over time were significantly lower in the older than in the younger age group, which was not the case with manual segmentation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2014-02-14

    Next-generation active immunization approach for synucleinopathies: implications for Parkinson's disease clinical trials

    ✓ Peer-reviewed Inflammation and the immune system Acta neuropathologica

    Key finding: The discovery that α-synuclein (α-syn) can transmit from cell to cell in a prion-like fashion suggests that immunization might be a viable option for the treatment of synucleinopathies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2014-02-12

    Depressive symptoms predict incident dementia during short- but not long-term follow-up period

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Whether depression is a long-term risk factor for dementia or represents a dementia prodrome is unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2014-02-12

    Geniposide ameliorates learning memory deficits, reduces tau phosphorylation and decreases apoptosis via GSK3β pathway in streptozotocin-induced alzheimer rat model

    ✓ Peer-reviewed Drug development Brain pathology (Zurich, Switzerland)

    Key finding: Our previous work showed that prior ICV treatment of glucagon-like peptide-1 (GLP-1) could prevent STZ-induced learning memory impairment and tau hyperphosphorylation in the rat brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2014-02-11

    In vivo evaluation of a novel tau imaging tracer for Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans European journal of nuclear medicine and molecular imaging

    Key finding: (18)F-THK523 does not bind to Aβ in vivo, while following the known distribution of paired helical filaments (PHF)-tau in the brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2014-02-11

    The impact of environmental factors in severe psychiatric disorders

    ✓ Peer-reviewed Hippocampus size on brain scans Frontiers in neuroscience

    Key finding: These findings may lead to new therapeutic strategies influencing epigenetic targets in severe psychiatric disorders.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →