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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,701–17,725 of 27,380 studies, newest first · page 709 of 1096.

August 2014 8

  1. 2014-08-01

    Identification of structural determinants on tau protein essential for its pathological function: novel therapeutic target for tau immunotherapy in Alzheimer's disease

    ✓ Peer-reviewed Drug development Alzheimer's research & therapy

    Key finding: We have discovered defined determinants on mis-disordered truncated tau protein which are responsible for tau oligomerisation leading to neurofibrillary degeneration. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2014-08-01

    The role of hippocampal tau protein phosphorylation in isoflurane-induced cognitive dysfunction in transgenic APP695 mice

    ✓ Peer-reviewed Tau biomarkers Anesthesia and analgesia

    Key finding: Previous studies have shown that exposure to inhaled anesthetics can cause cognitive dysfunction, suggesting that general anesthesia might be a risk factor for the development of Alzheimer disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2014-08-01

    Update on the core and developing cerebrospinal fluid biomarkers for Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers Croatian medical journal

    Key finding: Despite numerous clinical trials investigating this disease, there is still no effective treatment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2014-08-01

    Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques

    ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of disease

    Key finding: However, the specific type of amyloid and mechanisms of amyloid pathogenesis remain unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2014-08-01

    Intracranial hypotension: clinical presentation, imaging findings, and imaging-guided therapy

    ✓ Peer-reviewed Digital health tools Current opinion in neurology

    Key finding: Recent findings Intracranial hypotension occurs spontaneously, following (lumbar) dural puncture, accidental dural opening, or excessive surgical cerebrospinal fluid drainage.

    Full summary, score breakdown and related studies → Original source

  6. 2014-08-01

    Post-stroke cognitive impairment: epidemiology, mechanisms and management

    ✓ Peer-reviewed How common it is Annals of translational medicine

    Key finding: The risk of post-stroke cognitive impairment is related to both the demographic factors like age, education and occupation and vascular factors. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2014-08-01

    Effect of 1 night of total sleep deprivation on cerebrospinal fluid β-amyloid 42 in healthy middle-aged men: a randomized clinical trial

    ✓ Peer-reviewed Treatments JAMA neurology

    Key finding: Sleep deprivation, or prolonged wakefulness, interferes with a physiological morning decrease in Aβ42.

    Full summary, score breakdown and related studies → Original source

  8. 2014-08-01

    The preclinical Alzheimer cognitive composite: measuring amyloid-related decline

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: In ADNI, Aβ-positive participants showed more decline than did Aβ-negative participants with regard to the ADCS-PACC score at 24 months (mean [SE] difference, -1.239 [0.522] [95% CI, -2.263 to -0.215]; P = .02). +3 more findings

    Full summary, score breakdown and related studies → Original source

July 2014 17

  1. 2014-07-31

    Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed Drug development Brain : a journal of neurology

    Key finding: Tau immunotherapy has therefore been proposed as a new therapeutic approach to Alzheimer's disease and encouraging results have been obtained by active or passive immunization of tau transgenic mice. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2014-07-31

    Serotonin in Parkinson's disease

    ✓ Peer-reviewed Risk factors Behavioural brain research

    Key finding: However, non-motor symptoms such as chronic fatigue, depression, dementia and sleep disturbances are also frequent and play a significant role with negative consequences in the quality of life of patients with Parkinson's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2014-07-30

    Recommendations of the Alzheimer's disease-related dementias conference

    ✓ Peer-reviewed Disparities Neurology

    Key finding: The National Alzheimer's Project Act, signed into law in 2011, mandates a National Plan to Address Alzheimer's Disease that is updated annually. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2014-07-29

    Dietary patterns and cognitive decline in an Australian study of ageing

    ✓ Peer-reviewed Prevention trials Molecular psychiatry

    Key finding: Higher baseline adherence to the AusMeDi was associated with better performance in the executive function cognitive domain after 36 months in apolipoprotein E (APOE) ɛ4 allele carriers (P<0.01). +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2014-07-29

    PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation

    ✓ Peer-reviewed Long-term cohort studies Annals of neurology

    Key finding: Much of the genetic basis for Alzheimer disease (AD) is unexplained. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2014-07-29

    Use of an online community to provide support to caregivers of people with dementia

    ✓ Peer-reviewed Disparities Journal of gerontological social work

    Key finding: This is especially important for persons from ethnic minority groups, because linguistically and culturally appropriate information is often not available. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2014-07-29

    Systemic inflammation, blood-brain barrier vulnerability and cognitive/non-cognitive symptoms in Alzheimer disease: relevance to pathogenesis and therapy

    ✓ Peer-reviewed Caregiving Frontiers in aging neuroscience

    Key finding: These symptoms often exhibit sudden onset and tend to fluctuate over time, and in many cases, they are triggered by an infection in peripheral organs, suggesting that inflammation plays an important role in the pathogenesis of these non-cognitive symptoms. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2014-07-29

    Regular fish consumption and age-related brain gray matter loss

    ✓ Peer-reviewed Brain scans and imaging American journal of preventive medicine

    Key finding: Dietary consumption of baked or broiled fish is related to larger gray matter volumes independent of omega-3 fatty acid content. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2014-07-25

    Atrophy of the cholinergic basal forebrain in dementia with Lewy bodies and Alzheimer's disease dementia

    ✓ Peer-reviewed Cognitive tests and assessment Journal of neurology

    Key finding: We aimed to investigate subregional atrophy of the BF in DLB in vivo and compare it to the pattern of BF atrophy in AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2014-07-24

    Screening of CHCHD10 in a French cohort confirms the involvement of this gene in frontotemporal dementia with amyotrophic lateral sclerosis patients

    ✓ Peer-reviewed Risk factors Neurobiology of aging

    Key finding: Although the frequency of mutations is low in this series (2.6%), our work suggests that CHCHD10 mutations should be searched particularly when bulbar symptoms are present at onset.

    Full summary, score breakdown and related studies → Original source

  11. 2014-07-23

    TYROBP in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurobiology

    Key finding: TYROBP acts as a signaling adaptor protein for numerous cell surface receptors, playing important roles in signal transduction in dendritic cells, osteoclasts, macrophages, and microglia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2014-07-22

    Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome

    ✓ Peer-reviewed Inflammation and the immune system Autophagy

    Key finding: Microglia, a primary immune cell in brain, ingests and degrades extracellular Aβ fibrils via the lysosomal system. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2014-07-22

    Upregulation of TREM2 ameliorates neuropathology and rescues spatial cognitive impairment in a transgenic mouse model of Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    Key finding: To date, the expression and biologic functions of TREM2 under AD context remain largely unknown. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2014-07-22

    Traumatic brain injury and risk of dementia in older veterans

    ✓ Peer-reviewed Prevention and risk Neurology

    Key finding: 16% of veterans with a TBI history developed dementia within 9 years, compared to 10% of veterans without TBI +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2014-07-21

    A web-based non-intrusive ambient system to measure and classify activities of daily living

    ✓ Peer-reviewed Cognitive tests and assessment Journal of medical Internet research

    Key finding: To provide effective care, they need to know how patients cope with ADL, in particular, the estimation of risks associated with the cognitive decline. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2014-07-21

    Reconsidering harbingers of dementia: progression of parietal lobe white matter hyperintensities predicts Alzheimer's disease incidence

    ✓ Peer-reviewed Vascular contributions Neurobiology of aging

    Key finding: Cross-sectional volumetric measures of WMH, particularly in the parietal lobes, are associated with increased risk of AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2014-07-20

    Huntington's disease is a four-repeat tauopathy with tau nuclear rods

    ✓ Peer-reviewed Disease mechanisms Nature medicine

    Key finding: An imbalance of tau isoforms containing either three or four microtubule-binding repeats causes frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17) in families with intronic mutations in the MAPT gene. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →