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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,601–17,625 of 27,380 studies, newest first · page 705 of 1096.

October 2014 3

  1. 2014-10-01

    Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease

    ✓ Peer-reviewed Genetics JAMA psychiatry

    Key finding: The CSF levels of Aβ42 but not total and phosphorylated tau were lower in APOE ε4 carriers compared with noncarriers irrespective of diagnostic group (cohort A). +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2014-10-01

    Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid β-amyloid 42: a cross-validation study against amyloid positron emission tomography

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: The agreement between Aβ classification with CSF Aβ42 and 18F-flutemetamol positron emission tomography was very high (κ = 0.85). +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2014-10-01

    Brain PET in the diagnosis of Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Clinical nuclear medicine

    Key finding: FDG-PET and amyloid PET imaging are valuable in the assessment of patients with Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

September 2014 22

  1. 2014-09-30

    Classifying neurocognitive disorders: the DSM-5 approach

    ✓ Peer-reviewed Getting a diagnosis Nature reviews. Neurology

    Key finding: As a result, there is now an array of terms to describe cognitive syndromes, various definitions for the same syndrome, and often multiple criteria to determine a specific aetiology.

    Full summary, score breakdown and related studies → Original source

  2. 2014-09-29

    Resting-state networks link invasive and noninvasive brain stimulation across diverse psychiatric and neurological diseases

    ✓ Peer-reviewed Brain scans and imaging Proceedings of the National Academy of Sciences of the United States of America

    Key finding: These results suggest that resting-state functional connectivity may be useful for translating therapy between stimulation modalities, optimizing treatment, and identifying new stimulation targets.

    Full summary, score breakdown and related studies → Original source

  3. 2014-09-28

    Multi-faced neuroprotective effects of geniposide depending on the RAGE-mediated signaling in an Alzheimer mouse model

    ✓ Peer-reviewed Disease mechanisms Neuropharmacology

    Key finding: The results indicate that geniposide treatment significantly suppresses RAGE-dependent signaling (activation of ERK and IκB/NF-κB), the production of tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) and cerebral Aβ accumulation in vivo. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2014-09-26

    Air pollution and your brain: what do you need to know right now

    ✓ Peer-reviewed Inflammation and the immune system Primary health care research & development

    Key finding: The effects of air pollution on the central nervous system (CNS) are not broadly recognized. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2014-09-26

    Microglial pathology

    ✓ Peer-reviewed Inflammation and the immune system Acta neuropathologica communications

    Key finding: It also provides examples of microglial changes that have been observed in laboratory animals during aging and in some experimentally induced lesions and disease models. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2014-09-26

    Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part II

    ✓ Peer-reviewed Down syndrome and Alzheimer's Molecules (Basel, Switzerland)

    Key finding: DYRK1A/1B kinases are known to be involved in the regulation of various molecular pathways associated with oncology, neurodegenerative diseases (such as Alzheimer disease, AD, or other tauopathies), genetic diseases (such as Down Syndrome, DS), as well as diseases involved in abnormal pre-mRNA splicing.

    Full summary, score breakdown and related studies → Original source

  7. 2014-09-24

    The Alzheimer disease protective mutation A2T modulates kinetic and thermodynamic properties of amyloid-β (Aβ) aggregation

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Assuming a crucial role of amyloid-Aβ in neurodegeneration, we hypothesized that both A2V and A2T mutations cause distinct changes in Aβ properties that may at least partially explain these completely different phenotypes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2014-09-24

    Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: We recently identified a rare APP variant encoding an alanine-to-threonine substitution at residue 673 (A673T) that confers protection against development of AD (Jonsson, T., Atwal, J. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2014-09-24

    Clinical subtypes of chronic traumatic encephalopathy: literature review and proposed research diagnostic criteria for traumatic encephalopathy syndrome

    ✓ Peer-reviewed Prevention and risk Alzheimer's research & therapy

    Key finding: The clinical features include impairments in mood (for example, depression and hopelessness), behavior (for example, explosivity and violence), cognition (for example, impaired memory, executive functioning, attention, and dementia), and, less commonly, motor functioning (for example, parkinsonism, ataxia, and dysarthria). +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2014-09-24

    Self-reported memory complaints: implications from a longitudinal cohort with autopsies

    ✓ Peer-reviewed Genetics Neurology

    Key finding: As potential harbingers of future cognitive decline, physicians should query and monitor SMCs from their older patients.

    Full summary, score breakdown and related studies → Original source

  11. 2014-09-22

    PICALM modulates autophagy activity and tau accumulation

    ✓ Peer-reviewed Genetics Nature communications

    Key finding: Genome-wide association studies have identified several loci associated with Alzheimer's disease (AD), including proteins involved in endocytic trafficking such as PICALM/CALM (phosphatidylinositol binding clathrin assembly protein). +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2014-09-22

    Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2

    ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Our data, therefore, directly link impaired protein degradation to inclusion formation that is associated with synaptic dysfunction and cognitive deficits.

    Full summary, score breakdown and related studies → Original source

  13. 2014-09-22

    A review on Alzheimer's disease pathophysiology and its management: an update

    ✓ Peer-reviewed Brain tissue and pathology Pharmacological reports : PR

    Key finding: Pathologically it is characterized by intracellular neurofibrillary tangles and extracellular amyloidal protein deposits contributing to senile plaques. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2014-09-20

    Relationship between loneliness, psychiatric disorders and physical health ? A review on the psychological aspects of loneliness

    ✓ Peer-reviewed Risk factors Journal of clinical and diagnostic research : JCDR

    Key finding: Since the time of dawn, loneliness is perceived as a global human phenomenon. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2014-09-19

    Synaptic Plasticity and Memory: New Insights from Hippocampal Left-Right Asymmetries

    ✓ Peer-reviewed Disease mechanisms The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry

    Key finding: Activity-dependent modification of these synapses is thought to participate in circuit formation and remodeling during development, and further plastic changes may support memory encoding in adulthood. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2014-09-19

    Alzheimer presenilin-1 mutations dramatically reduce trimming of long amyloid β-peptides (Aβ) by γ-secretase to increase 42-to-40-residue Aβ

    ✓ Peer-reviewed Biomarkers The Journal of biological chemistry

    Key finding: The presenilin-containing γ-secretase complex produces the amyloid β-peptide (Aβ) through intramembrane proteolysis, and >100 presenilin mutations are associated with familial early-onset Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2014-09-19

    Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies

    ✓ Peer-reviewed Tau biomarkers Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: At present there is no effective treatment available for these progressive neurodegenerative diseases which are clinically characterized by dementia in mid to old-age. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2014-09-18

    Effects of cannabidiol in the treatment of patients with Parkinson’s disease: An exploratory double-blind trial

    ✓ Peer-reviewed Clinical trials Journal of Psychopharmacology

    Key finding: We found no statistically significant differences in UPDRS scores, plasma BDNF levels or H(1)-MRS measures. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2014-09-18

    Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Neuron

    Key finding: In humans, LRP6 and Wnt signaling are significantly downregulated in AD brains, likely by a mechanism that depends on amyloid-β. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2014-09-17

    Consensus on quality indicators to assess the organisation of palliative cancer and dementia care applicable across national healthcare systems and selected by international experts

    ✓ Peer-reviewed End-of-life care BMC health services research

    Key finding: International experts selected a set of 23 QIs for the organisation of palliative care.

    Full summary, score breakdown and related studies → Original source

  21. 2014-09-17

    Relation of DASH- and Mediterranean-like dietary patterns to cognitive decline in older persons

    ✓ Peer-reviewed Prevention trials Neurology

    Key finding: These findings support the hypothesis that both the DASH and Mediterranean diet patterns are associated with slower rates of cognitive decline in the same cohort of older persons. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2014-09-16

    Tauopathy PET and amyloid PET in the diagnosis of chronic traumatic encephalopathies: studies of a retired NFL player and of a man with FTD and a severe head injury

    ✓ Peer-reviewed Disease mechanisms Translational psychiatry

    Key finding: CTE was suspected clinically, and [(18)F]-T807 PET imaging revealed striatal and nigral [(18)F]-T807 retention consistent with the presence of tauopathy. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →