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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,776–16,800 of 27,380 studies, newest first · page 672 of 1096.

August 2015 4

  1. 2015-08-01

    TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD

    ✓ Peer-reviewed Lewy body dementia Science (New York, N.Y.)

    Key finding: In contrast to RBPs that regulate splicing of conserved exons, we found that TDP-43 repressed the splicing of nonconserved cryptic exons, maintaining intron integrity. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2015-08-01

    Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial

    ✓ Peer-reviewed Prevention and risk JAMA

    Key finding: Among sedentary older adults, a 24-month moderate-intensity physical activity program compared with a health education program did not result in improvements in global or domain-specific cognitive function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2015-08-01

    Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial

    ✓ Peer-reviewed Treatments JAMA

    Key finding: Among older persons with AMD, oral supplementation with LCPUFAs or lutein/zeaxanthin had no statistically significant effect on cognitive function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2015-08-01

    Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Similar to findings in adult mutation carriers, in the later preclinical and clinical stages of ADAD, mutation-carrying children were distinguished from control individuals by significantly higher plasma Aβ1-42 levels (mean [SD]: carriers, 18.8 [5.1] pg/mL and noncarriers, 13.1 [3.2] pg/mL; P Conclusions and relevance Children at genetic risk for ADAD have functional and structural brain changes and abnormal levels of plasma Aβ1-42. +1 more finding

    Full summary, score breakdown and related studies → Original source

July 2015 21

  1. 2015-07-31

    Depression of Family Caregivers Is Associated with Disagreements on Life-Sustaining Preferences for Treating Patients with Dementia

    ✓ Peer-reviewed End-of-life care PloS one

    Key finding: The preferences of end-of-life issues differed greatly between dementia patients and their caregivers. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2015-07-31

    Traffic-Related Air Pollution and Dementia Incidence in Northern Sweden: A Longitudinal Study

    ✓ Peer-reviewed Risk factors Environmental health perspectives

    Key finding: If the associations we observed are causal, then air pollution from traffic might be an important risk factor for vascular dementia and Alzheimer's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2015-07-30

    NIH Calls for National Plan for Cancer Rehab

    ✓ Peer-reviewed Health systems and care delivery Oncology Times

    Key finding: There is explosive growth in the number of older Americans, who are at higher risk for cancer. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2015-07-29

    A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders

    ✓ Peer-reviewed Digital health tools Frontiers in cellular neuroscience

    Key finding: It is becoming increasingly clear that the regulated activity of MMP-9 is critical for central nervous system (CNS) development. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2015-07-29

    Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice

    ✓ Peer-reviewed Inflammation and the immune system Antioxidants & redox signaling

    Key finding: These data reveal a link between reduced glucocerebrosidase and the development of α-synucleinopathy and pathophysiological abnormalities in mice, and support the development of GCase therapeutics to reduce α-synucleinopathy in PD and related disorders. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2015-07-29

    Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection

    ✓ Peer-reviewed Inflammation and the immune system Biochemical pharmacology

    Key finding: We will focus on the α7 nAChR subtype, which has been implicated in neuroprotection, synaptic plasticity and neuronal survival, and is considered as a potential therapeutic target for several neurological diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2015-07-29

    Comorbidity as a driver of adverse outcomes in people with chronic kidney disease

    ✓ Peer-reviewed Caregiving Kidney international

    Key finding: Chronic kidney disease (CKD) is associated with poor outcomes, perhaps due to a high burden of comorbidity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2015-07-28

    Ambient air pollution and neurotoxicity on brain structure: Evidence from women's health initiative memory study

    ✓ Peer-reviewed Risk factors Annals of neurology

    Key finding: PM2.5 exposure may contribute to WM loss in older women. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2015-07-28

    Rare coding mutations identified by sequencing of Alzheimer disease genome-wide association studies loci

    ✓ Peer-reviewed Genetics Annals of neurology

    Key finding: Targeted sequencing of confirmed GWAS loci revealed an excess burden of deleterious coding mutations in LOAD, with the greatest burden observed in ABCA7 and BIN1. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2015-07-27

    Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin

    ✓ Peer-reviewed Brain tissue and pathology Nature medicine

    Key finding: Our results demonstrate that neutrophils contribute to Alzheimer's disease pathogenesis and cognitive impairment and suggest that the inhibition of neutrophil trafficking may be beneficial in Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  11. 2015-07-26

    Clinical use of amyloid-positron emission tomography neuroimaging: Practical and bioethical considerations

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: To best address the multifaceted issues associated with amyloid-PET neuroimaging, we recommend this technology be used only by experienced imaging and treating physicians in appropriately selected patients and only in the context of a comprehensive clinical evaluation with adequate explanations before and after the scan.

    Full summary, score breakdown and related studies → Original source

  12. 2015-07-26

    Implementation of improvement strategies in palliative care: an integrative review

    ✓ Peer-reviewed End-of-life care Implementation science : IS

    Key finding: This review is one of the first to provide an overview of the available literature in relation to strategies used to improve the organisation of palliative care. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2015-07-26

    Stereotactic brain injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer's disease dementia: A phase 1 clinical trial

    ✓ Peer-reviewed Clinical safety Alzheimer's & dementia (New York, N. Y.)

    Key finding: Administration of hUCB-MSCs into the hippocampus and precuneus by stereotactic injection was feasible, safe, and well tolerated.

    Full summary, score breakdown and related studies → Original source

  14. 2015-07-25

    Corticobasal Syndrome in a Family with Early-Onset Alzheimer's Disease Linked to a Presenilin-1 Gene Mutation

    ✓ Peer-reviewed Risk genes beyond APOE Movement disorders clinical practice

    Key finding: Two of three examined members of this family presented with the usual amnestic pattern. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2015-07-24

    Cerebral small vessel disease is related to disturbed 24-h activity rhythms: a population-based study

    ✓ Peer-reviewed Long-term cohort studies European journal of neurology

    Key finding: Cerebral small vessel disease is common in elderly persons. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2015-07-24

    Amyloid-β 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials

    ✓ Peer-reviewed Genetics Neurology

    Key finding: The (11)C-PiB-PET imaging results demonstrated reduction of fibrillar Aβ accumulation in patients with Alzheimer disease treated with bapineuzumab; however, as no clinical benefit was observed, the findings are consistent with the hypotheses that bapineuzumab may not have been initiated early enough in the disease course, the doses were insufficient, or the most critical Aβ species were inadequately targeted. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2015-07-23

    Music, memory and mechanisms in Alzheimer’s disease: Figure 1

    ✓ Peer-reviewed Treatments Brain

    Key finding: These same brain areas were then assessed in a cohort of patients with Alzheimer’s disease versus a healthy older reference group, using a region of interest approach combined with standard structural (MRI), metabolic (fluorodeoxyglucose-PET) and amyloid ligand (florbetapir-PET) neuroimaging. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2015-07-23

    Protecting cognition from aging and Alzheimer's disease: a computerized cognitive training combined with reminiscence therapy

    ✓ Peer-reviewed Cognitive tests and assessment International journal of geriatric psychiatry

    Key finding: Our results corroborate the positive effect of pb-CT and its maintenance primarily on memory in HE and MCI participants that did not seem to be potentiated by RT. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2015-07-23

    Collective physician perspectives on non-oral medication approaches for the management of clinically relevant unresolved issues in Parkinson's disease: Consensus from an international survey and discussion program

    ✓ Peer-reviewed Clinical safety Parkinsonism & related disorders

    Key finding: Key take-home points are: • Patients requiring levodopa >5 times daily who have severe, troublesome 'off' periods (>1-2 h/day) despite optimal oral/transdermal levodopa or non-levodopa-based therapies should be referred for specialist assessment even if disease duration is <4 years. • Cognitive decline related to non-motor fluctuations is an indication for device-aided therapies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2015-07-23

    Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Scientific reports

    Key finding: Here we have implemented a novel meta-analysis approach to identify differentially expressed genes (DEGs) in published datasets comprising 450 late onset AD (LOAD) brains and 212 controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2015-07-23

    Prevention of sporadic Alzheimer's disease: lessons learned from clinical trials and future directions

    ✓ Peer-reviewed Prevention and risk The Lancet. Neurology

    Key finding: Interventions that have even quite modest effects at the individual level could drastically reduce the future burden of dementia associated with Alzheimer's disease at the population level.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →