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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,376–16,400 of 27,380 studies, newest first · page 656 of 1096.

January 2016 25

  1. 2016-01-20

    Profiling Speech and Pausing in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

    ✓ Peer-reviewed Digital health tools PloS one

    Key finding: This study demonstrated the use of speech measures in the identification of those with an oral-motor deficit, and showed the usefulness of performing a relatively simple reading test to assess speech versus pause behaviors across the ALS-FTD disease continuum. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-01-19

    Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease

    ✓ Peer-reviewed Genetics Genome medicine

    Key finding: We have characterized changes in DNA methylation in the superior temporal gyrus of patients with Alzheimer's disease, highlighting novel loci that facilitate better characterization of pathways and mechanisms underlying Alzheimer's disease pathogenesis, and improve our understanding of epigenetic signatures that may contribute to the development of disease.

    Full summary, score breakdown and related studies → Original source

  3. 2016-01-19

    High dietary advanced glycation end products are associated with poorer spatial learning and accelerated Aβ deposition in an Alzheimer mouse model

    ✓ Peer-reviewed Disease mechanisms Aging cell

    Key finding: We found that AD-like model mice on high-AGE diet due to irradiation had significantly poorer memory, higher hippocampal levels of insoluble Aβ42 and AGEs as well as higher levels of oxidative stress on vascular walls, compared to littermates fed an isocaloric diet.

    Full summary, score breakdown and related studies → Original source

  4. 2016-01-18

    Management of psychiatric and neurological comorbidities in epilepsy

    ✓ Peer-reviewed Vascular contributions Nature reviews. Neurology

    Key finding: Psychiatric and neurological comorbidities are relatively common and often co-exist in people with epilepsy (PWE). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2016-01-18

    Suspected non-Alzheimer disease pathophysiology--concept and controversy

    ✓ Peer-reviewed Genetics Nature reviews. Neurology

    Key finding: APOE*ε4 is underrepresented in individuals with SNAP compared with amyloid-positive individuals.

    Full summary, score breakdown and related studies → Original source

  6. 2016-01-16

    TREM2 Overexpression has No Improvement on Neuropathology and Cognitive Impairment in Aging APPswe/PS1dE9 Mice

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurobiology

    Key finding: Previously, we showed that overexpression of triggering receptor expressed on myeloid cells 2 (TREM2), a microglia-specific immune receptor, in the brain of a middle-aged (7 months old) APPswe/PS1dE9 mice could ameliorate Alzheimer's disease (AD)-related neuropathology by enhancement of microglial amyloid-β (Aβ) phagocytosis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2016-01-15

    Heterogeneity of Treatment Response to Citalopram for Patients With Alzheimer's Disease With Aggression or Agitation: The CitAD Randomized Clinical Trial

    ✓ Peer-reviewed Treatments The American journal of psychiatry

    Key finding: Considering several covariates together allowed the identification of responders. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2016-01-14

    Amyloid Hypothesis: Is There a Role for Antiamyloid Treatment in Late-Life Depression?

    ✓ Peer-reviewed Brain scans and imaging The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: In patients without history of depression, amyloid accumulation during the preclinical phase of Alzheimer disease (AD) may result in the prodromal depression syndrome that precedes cognitive impairment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2016-01-13

    Rivastigmine for gait stability in patients with Parkinson's disease (ReSPonD): a randomised, double-blind, placebo-controlled, phase 2 trial

    ✓ Peer-reviewed Clinical safety The Lancet. Neurology

    Key finding: At week 32, compared with patients assigned to placebo (59 assessed), those assigned to rivastigmine (55 assessed) had improved step time variability for normal walking (ratio of geometric means 0.72, 95% CI 0.58-0.88; p=0.002) and the simple dual task (0.79; 0.62-0.99; p=0.045). +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2016-01-13

    Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations

    ✓ Peer-reviewed Getting a diagnosis The Cochrane database of systematic reviews

    Key finding: We did not apply any language or date restrictions to the electronic searches, and we did not use any methodological filters as a method to restrict the search overall. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2016-01-12

    Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system Journal of Neuroscience

    Key finding: This promotes a pathogenic cycle by which C3 in turn interacts with neuronal and microglial C3aR to alter cognitive function and impair Aβ phagocytosis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2016-01-12

    Hippocampal harms, protection and recovery following regular cannabis use

    ✓ Peer-reviewed Hippocampus size on brain scans Translational psychiatry

    Key finding: Shifting policies towards legalisation of cannabis for therapeutic and recreational use raise significant ethical issues for health-care providers seeking evidence-based recommendations. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2016-01-12

    Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurodegeneration

    Key finding: The discovery that heterozygous missense mutations in the gene encoding triggering receptor expressed on myeloid cells 2 (TREM2) are risk factors for Alzheimer's disease (AD), with only the apolipoprotein E (APOE) ε4 gene allele conferring a higher risk, has led to increased interest in immune biology in the brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2016-01-11

    Effect of Donepezil, Tacrine, Galantamine and Rivastigmine on Acetylcholinesterase Inhibition in Dugesia tigrina

    ✓ Peer-reviewed Treatments Molecules (Basel, Switzerland)

    Key finding: Galantamine showed high anticholinesterasic activity when compared to the other drugs, with a reduction of 0.05 μmol·min(-1) and 63% of convulsant activity, presenting screw-like movement and hypokinesia, with pLMV of 65 crossed lines during 5 min. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2016-01-11

    Soluble TREM-2 in cerebrospinal fluid from patients with multiple sclerosis treated with natalizumab or mitoxantrone

    ✓ Peer-reviewed TREM2 and immune genetics Multiple sclerosis (Houndmills, Basingstoke, England)

    Key finding: Microglia-mediated proteolysis of the triggering receptor expressed on myeloid cells-2 (TREM-2) produces soluble TREM-2 (sTREM-2) that can be measured in cerebrospinal fluid (CSF) samples. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2016-01-11

    The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: Whether genetic risk factors for AD exert an effect on these subcortical structures independent of clinical status has not been fully investigated. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2016-01-11

    Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status

    ✓ Peer-reviewed Genetics Acta neuropathologica

    Key finding: Low frequency coding variants in TREM2 are associated with increased Alzheimer disease (AD) risk, while loss of functions mutations in the gene lead to an autosomal recessive early-onset dementia, named Nasu-Hakola disease (NHD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2016-01-06

    Hallucinations, loneliness, and social isolation in Alzheimer's disease

    ✓ Peer-reviewed Risk factors Cognitive neuropsychiatry

    Key finding: More hallucinatory experiences, social isolation, and loneliness were found in the AD group than in the healthy control group. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2016-01-05

    GWAS-Linked Loci and Neuroimaging Measures in Alzheimer's Disease

    ✓ Peer-reviewed Genetics Molecular neurobiology

    Key finding: As a result, single nucleotide polymorphisms (SNPs) at rs983392 within MS4A6A and rs11218343 within SOLR1 were both associated with the percentage of increase in the volume of left inferior temporal regions in the follow-up study. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2016-01-05

    Irritable Bowel Syndrome Is Associated with an Increased Risk of Dementia: A Nationwide Population-Based Study

    ✓ Peer-reviewed Digital health tools PloS one

    Key finding: IBS is associated with an increased risk of dementia, and this effect is obvious only in patients who are ≥50 years old. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2016-01-05

    Olfaction in People with Down Syndrome: A Comprehensive Assessment across Four Decades of Age

    ✓ Peer-reviewed Down syndrome and Alzheimer's PloS one

    Key finding: However, specificity of this olfactory profile to DS should be considered with some caution because cognition was not evaluated in all DS participants and comparison with a control group of non-DS individuals having cognitive disabilities was lacking.

    Full summary, score breakdown and related studies → Original source

  22. 2016-01-04

    A systematic review of social support interventions for caregivers of people with dementia: Are they doing what they promise?

    ✓ Peer-reviewed Caregiving Maturitas

    Key finding: Although multi-component social support interventions may improve caregiver well-being, there is insufficient evidence to conclude whether a change in social support is the underlying mediating factor. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2016-01-04

    Statins for the prevention of dementia

    ✓ Peer-reviewed Prevention and risk The Cochrane database of systematic reviews

    Key finding: Main results We included two trials with 26,340 participants aged 40 to 82 years of whom 11,610 were aged 70 or older. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2016 year only

    End-of-Life Care and Psychiatry: Current Trends and Future Directions in India

    ✓ Peer-reviewed End-of-life care Mens sana monographs

    Key finding: The psychiatrist can play a significant role in each of the above domains in EOLC.

    Full summary, score breakdown and related studies → Original source

  25. 2016 year only

    Costs, Staffing, and Services of Assisted Living in the United States: A Literature Review

    ✓ Peer-reviewed Health systems and care delivery The health care manager

    Key finding: Unfortunately, Medicare does not pay for ALFs. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →