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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,001–17,025 of 27,380 studies, newest first · page 681 of 1096.

April 2015 25

  1. 2015-04-27

    Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization

    ✓ Peer-reviewed Disease mechanisms Molecular nutrition & food research

    Key finding: Scope Grape seed polyphenol extract (GSPE) is receiving increasing attention for its potential preventative and therapeutic roles in Alzheimer's disease (AD) and other age-related neurodegenerative disorders. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2015-04-27

    Long-term treatment with active Aβ immunotherapy with CAD106 in mild Alzheimer's disease

    ✓ Peer-reviewed Treatments Alzheimer's research & therapy

    Key finding: The CAD106 first-in-human study demonstrated a favorable safety profile and promising antibody response. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2015-04-27

    The N-terminal pro B-type natriuretic peptide, and risk of dementia and cognitive decline: a 10-year follow-up study in the general population

    ✓ Peer-reviewed Long-term cohort studies Journal of neurology, neurosurgery, and psychiatry

    Key finding: The N-terminal pro B-type natriuretic peptide (NT-proBNP) has a well-documented prognostic value for cardiovascular disease (CVD) and higher levels are associated with cognitive-dysfunction in patients with CVD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2015-04-27

    Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE

    ✓ Peer-reviewed Down syndrome and Alzheimer's The Journal of biological chemistry

    Key finding: Here, we report that Dyrk1A was truncated at the C terminus and was associated with overactivation of calpain I in AD brain. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2015-04-27

    Hydration water mobility is enhanced around tau amyloid fibers

    ✓ Peer-reviewed Brain scans and imaging Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Fibers formed by the hexapeptide (306)VQIVYK(311) were taken as a model for the tau fiber core and studied by molecular dynamics simulations, revealing that hydration water dynamics around the core domain is significantly reduced after fiber formation.

    Full summary, score breakdown and related studies → Original source

  6. 2015-04-25

    Cerebrospinal fluid biomarkers and cerebral atrophy in distinct clinical variants of probable Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Neurobiology of aging

    Key finding: Bootstrapping revealed no differences in the prevalence of abnormal CSF total-tau and phosphorylated-tau between probable AD variants (range total-tau: 84.9%-92.3%, phosphorylated-tau: 79.2%-93.1%, p > 0.05). +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2015-04-25

    Rivastigmine for mild cognitive impairment in Parkinson disease: a placebo-controlled study

    ✓ Peer-reviewed Cognitive tests and assessment Movement disorders : official journal of the Movement Disorder Society

    Key finding: Mild cognitive impairment (MCI) in Parkinson's disease (PD) may be associated with subtle functional impairment and worse quality of life. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2015-04-25

    Validation of the Identification and Intervention for Dementia in Elderly Africans (IDEA) cognitive screen in Nigeria and Tanzania

    ✓ Peer-reviewed Disparities BMC geriatrics

    Key finding: The IDEA cognitive screen performed well in these populations and should prove useful in screening for dementia and delirium in other areas of sub-Saharan Africa. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2015-04-24

    Florbetapir positron emission tomography and cerebrospinal fluid biomarkers

    ✓ Peer-reviewed Tau biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: In HC and MCI subjects, FBP PET anterior and posterior cingulate and composite standard uptake value ratios correlated with CSF amyloid beta (Aβ1-42) and tau/Aβ1-42 ratios. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2015-04-24

    The contribution of astrocytes and microglia to traumatic brain injury

    ✓ Peer-reviewed Inflammation and the immune system British journal of pharmacology

    Key finding: Brain injuries are highly heterogeneous and can also trigger other neurological complications, including epilepsy, depression and dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2015-04-24

    Genetic risk of neurodegenerative diseases is associated with mild cognitive impairment and conversion to dementia

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Neurodegenerative diseases are a major cause of cognitive impairment and can ultimately lead to dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2015-04-24

    Development and evaluation of a multiplexed mass spectrometry based assay for measuring candidate peptide biomarkers in Alzheimer's Disease Neuroimaging Initiative (ADNI) CSF

    ✓ Peer-reviewed Mild cognitive impairment Proteomics. Clinical applications

    Key finding: These data provide potential insights into the biology of CSF in AD and MCI progression and provide a novel tool for AD researchers and clinicians working to improve diagnostic accuracy, evaluation of treatment efficacy, and early diagnosis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2015-04-23

    Aberrant functional connectivity of default-mode network in type 2 diabetes patients

    ✓ Peer-reviewed Brain scans and imaging European radiology

    Key finding: Patients showed increased connectivity around the medial prefrontal cortex in the anterior sub-network, but decreased connectivity around the posterior cingulate cortex in the posterior sub-network. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2015-04-23

    General practitioners perceptions on advance care planning for patients living with dementia

    ✓ Peer-reviewed End-of-life care BMC palliative care

    Key finding: Optimal timing of ACP discussions should be determined by the readiness of the patient and family carer to face end of life. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2015-04-23

    Quick Bites: Let the Food Label Be Your Guide Through the Grocery Store Jungle

    ✓ Peer-reviewed Risk factors Not indexed

    Key finding: Nutrition Facts labels help cut through confusing grocery-store marketing and make it easier to choose foods that fit your health goals and budget. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2015-04-22

    Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease

    ✓ Peer-reviewed Brain tissue and pathology Annals of neurology

    Key finding: Diagnoses of dementia, probable AD, and MCI in 636 autopsied subjects from the Religious Order Study and the Rush Memory and Aging Project were based on clinical evaluation and cognitive performance tests. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2015-04-22

    Relation between subcortical grey matter atrophy and conversion from mild cognitive impairment to Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Journal of neurology, neurosurgery, and psychiatry

    Key finding: Analysis of variances, adjusted for sex and age, showed that all structures, except the globus pallidus, were smaller in AD than in controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2015-04-22

    Aerobic exercise to improve cognitive function in older people without known cognitive impairment

    ✓ Peer-reviewed Prevention and risk The Cochrane database of systematic reviews

    Key finding: Also, we performed analyses including only trials in which an increase in the cardiovascular fitness of participants had been demonstrated. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2015-04-21

    Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA

    ✓ Peer-reviewed Prevention and risk Frontiers in aging neuroscience

    Key finding: The purpose of this review is to highlight how a detailed understanding of these effects is essential to improving understanding of their therapeutic potential. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2015-04-20

    TREM2 sustains microglial expansion during aging and response to demyelination

    ✓ Peer-reviewed TREM2 and immune genetics The Journal of clinical investigation

    Key finding: Like other tissue-resident macrophage populations, microglia express the surface receptor triggering receptor expressed on myeloid cells 2 (TREM2), which binds polyanions, such as dextran sulphate and bacterial LPS, and activates downstream signaling cascades through the adapter DAP12. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2015-04-19

    Abnormalities of fixation, saccade and pursuit in posterior cortical atrophy

    ✓ Peer-reviewed Risk factors Brain : a journal of neurology

    Key finding: In contrast to informal clinical evaluations of oculomotor dysfunction frequency (previous studies: 38%, current clinical examination: 33%), detailed eyetracking investigations revealed eye movement abnormalities in 80% of patients with posterior cortical atrophy (compared to 17% typical Alzheimer's disease, 5% controls). +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2015-04-18

    Biomarkers of lipid peroxidation in Alzheimer disease (AD): an update

    ✓ Peer-reviewed Mild cognitive impairment Archives of toxicology

    Key finding: Increasing evidence suggests that free radical-mediated oxidation of biological substrates is a key feature of Alzheimer's disease (AD) pathogenesis. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2015-04-17

    Effects of physical activity training in patients with Alzheimer's dementia: results of a pilot RCT study

    ✓ Peer-reviewed Cognitive tests and assessment PloS one

    Key finding: There is evidence that physical activity (PA) is of cognitive benefit to the ageing brain, but little is known on the effect in patients with Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2015-04-17

    Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study

    ✓ Peer-reviewed Biomarkers European journal of nuclear medicine and molecular imaging

    Key finding: The findings provide further in vivo evidence that astrocytosis occurs early in AD, preceding Aβ plaque deposition. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2015-04-16

    Amyloid deposition in Parkinson's disease and cognitive impairment: a systematic review

    ✓ Peer-reviewed Brain scans and imaging Movement disorders : official journal of the Movement Disorder Society

    Key finding: Substantial variability occurs in the prevalence of "PiB-positive" studies in subjects with Parkinsonism and cognitive impairment. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →