Newest studies

Bridging gaps in dementia care across southeastern Europe: Regional challenges, cross-border innovation, and implementation barriers

39/100 ✓ Peer-reviewed Disparities Journal of Public Health Research

Key finding: The Circle of Care Hub framework was developed to bridge coordination gaps and promote equitable, integrated dementia care by linking healthcare providers, social workers, and families. +4 more findings

• Health Equity
• Caregiving

Full summary, score breakdown and related studies → Original source

Intersecting Narratives in the Lives of Black Women Aging with Dementia

16/100 ⚠ Report — not peer-reviewed Disparities The Hastings Center Report

Key finding: Despite elevated risk profiles for dementia, Black women are often absent in cultural narratives about dementia. +3 more findings

• Health Equity

Scored 18 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

Full summary, score breakdown and related studies → Original source

Prevalence and progress of underdiagnosis of probable dementia: a repeated cross-sectional study in 19 European countries

52/100 ✓ Peer-reviewed Disparities BMC Medicine

Key finding: A significant reduction in underdiagnosis of dementia was observed between the two periods, consistent across most countries. +3 more findings

• Health Equity

Full summary, score breakdown and related studies → Original source

Relationship between cellular aging, perceived stress, and cardiometabolic disease risk in Black family caregivers of persons with dementia

41/100 ✓ Peer-reviewed Disparities Alzheimer s & Dementia

Key finding: Shorter telomeres were linked to stress, poor sleep, inflammation, and cardiometabolic markers. +4 more findings

• Caregiving

Full summary, score breakdown and related studies → Original source

Global Burden of Alzheimer's disease and other dementias in adults aged 65 years and older, 1991–2021: population-based study

68/100 ✓ Peer-reviewed Disparities Frontiers in Public Health

Key finding: The global mortality of ADRD among adults aged ≥65 years increased by 115%, from 6.5 (95% UI 1.5-18) per 100,000 population in 1991 to 14 (95% UI 3.5-37) per 100,000 population in 2021, with an Average Annual Percentage Change (AAPC) of 1.10% (95%CI 0.45%-1.76%). +4 more findings

Full summary, score breakdown and related studies → Original source

Alzheimer's disease and dementia in Japan: Epidemiological trends, regional disparities, and future projections

42/100 ✓ Peer-reviewed Disparities Alzheimer s & Dementia

Key finding: ADOD cases have steadily increased, with projections indicating continued growth by 2030. +4 more findings

• Health Equity
• Risk Factors

Full summary, score breakdown and related studies → Original source

Views of Family Caregivers on Advance Care Planning in Advanced Dementia Care in Hong Kong: A Qualitative Thematic Content Analysis Study

35/100 ✓ Peer-reviewed Caregiving Health Science Reports

Key finding: Emerging themes include (1) receptive to ACP, (2) mixed emotions, (3) barriers to ACP, (4) family consensus in decision-making, and (5) benefits of ACP. +4 more findings

• Caregiving
• End-of-Life Care

Full summary, score breakdown and related studies → Original source

Namaste Care Family for people with dementia and family−A randomized controlled trial

62/100 ✓ Peer-reviewed Caregiving Alzheimer s & Dementia

Key finding: The intervention group showed less discomfort (-1.06; 95% confidence interval [CI] = -1.88 to -0.23) and fewer sentinel events (-0.40; 95% CI = -0.64 to -0.16), specifically pneumonia (-0.08; 95% CI = -0.14, -0.02). +4 more findings

• Clinical Trials
• Caregiving

Full summary, score breakdown and related studies → Original source

Empathy and mental health distress in informal caregivers of dementia and stroke patients: a cross-sectional study

39/100 ✓ Peer-reviewed Caregiving Scientific Reports

Key finding: Informal caregivers of patients with neurodegenerative diseases are confronted with significant psychological distress. +4 more findings

• Caregiving

Full summary, score breakdown and related studies → Original source

Disease stage–specific atrophy markers in Alzheimer's disease

52/100 ✓ Peer-reviewed Brain scans and imaging Alzheimer s & Dementia

Key finding: Accelerated atrophy of medial temporal lobe subregions was evident already during preclinical AD. +4 more findings

Full summary, score breakdown and related studies → Original source

Classifying mild cognitive impairment from normal cognition: fMRI complexity matches tau PET performance

38/100 ✓ Peer-reviewed Brain scans and imaging Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

Key finding: The fMRI entropy classifier matched the tau PET model in accuracy and outperformed it in F1 score (0.64 vs. 0.61) and area under the curve (AUC; 0.73 vs. 0.67). +3 more findings

• Brain Scans
• Early Stage

Full summary, score breakdown and related studies → Original source

Loneliness trajectories and dementia risk: Insights from the HUNT cohort study

46/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

Key finding: In the fully adjusted model, the odds ratio (OR) for persistent loneliness was 1.47 (95% confidence interval [CI] 1.10, 1.95). +4 more findings

• Risk Factors
• Lifestyle

Full summary, score breakdown and related studies → Original source

Loneliness, social isolation, and effects on cognitive decline in patients with dementia: A retrospective cohort study using natural language processing

42/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

Key finding: Lower cognitive levels in lonely and socially isolated patients suggest that these factors may contribute to dementia progression. +1 more finding

• Lifestyle
• Diagnosis

Full summary, score breakdown and related studies → Original source

A vision transformer approach for fully automated and scalable dementia screening using clock drawing test images

45/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

Key finding: The ViT approach predicted dementia with 76.5% balanced accuracy, outperforming human-scored features (74.3%) and existing deep learning models (MiniVGG = 73.3%, MobileNetV2 = 72.3%, relevance factor variational autoencoder = 69.1%) on the TDRA dataset. +2 more findings

• Diagnosis

Full summary, score breakdown and related studies → Original source

Implications and opportunities regarding biological frameworks in overt and prodromal dementia with Lewy bodies

42/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia

Key finding: HIGHLIGHTS: DLB is a progressive neurodegenerative disease with varied clinical presentations. +4 more findings

• Other Dementias

Full summary, score breakdown and related studies → Original source

Community-based dementia screening initiative in Brunei: pilot study

42/100 ✓ Peer-reviewed Getting a diagnosis Journal of Gerontology and Geriatrics

Key finding: Community-based dementia screening using a questionnaire on risk factors, cognitive symptoms and the Mini-COG was feasible and acceptable in Brunei.

• Diagnosis
• Risk Factors

Full summary, score breakdown and related studies → Original source

Provider, Interdisciplinary Staff, and Patient Perspectives on the Potential for Cognitive Assessment and Care Plan Services in Primary Care

36/100 ✓ Peer-reviewed Getting a diagnosis Journal of Primary Care & Community Health

Key finding: acceptability, appropriateness, and feasibility. +4 more findings

• Diagnosis
• Care Services

Full summary, score breakdown and related studies → Original source

Unravelling the plasma proteome: Pioneering biomarkers for differential dementia diagnosis

47/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia

Key finding: Plasma phosphorylated Tau217 (pTau217) demonstrated the highest diagnostic accuracy for AD, DLB, and FTD (area under the curve [AUCs]: 0.9, 0.84, and 0.79, respectively). +4 more findings

• Diagnosis
• Biomarkers
• Brain Biology

Full summary, score breakdown and related studies → Original source

Alpha-synuclein seeding amplification assays in Lewy body dementia: a brief review

43/100 ✓ Peer-reviewed Getting a diagnosis Molecular Neurodegeneration

Key finding: Taken together, LBD is often misdiagnosed, especially at early disease stages. +1 more finding

• Other Dementias
• Diagnosis

Full summary, score breakdown and related studies → Original source

The Moderating Role of Dementia‐Related Fear in the Relationship Between Perceived Cognitive Decline and Motivation for Dementia Risk Reduction Behaviors in Community‐Dwelling Middle‐Aged and Older Adults

44/100 ✓ Peer-reviewed Prevention and risk International Journal of Geriatric Psychiatry

Key finding: A significant correlation was found between perceived cognitive decline and increased motivation to engage in dementia risk reduction behaviors (r = 0.44). +3 more findings

• Prevention
• Risk Factors

Full summary, score breakdown and related studies → Original source

Zerebrale Amyloidangiopathie

26/100 ✓ Peer-reviewed Treatments Neuroradiologie Scan

Key finding: Es gibt zunehmende Evidenz für ein „prionenähnliches Verhalten“ von beta-Amyloid, was zu iatrogener CAA führen kann. +4 more findings

• Treatments

Full summary, score breakdown and related studies → Original source

The Cell and Molecular Pathology of Tau Protein in Alzheimer’s Disease

29/100 ✓ Peer-reviewed Treatments Microscopy and Microanalysis

Key finding: As a result of multiple phosphorylation, Tau undergoes early conformational changes involving the bending of the intact amino (N)-terminus over the third repeated domain, which in turn was evidenced by positive immunolabeling with the monoclonal antibody Alz-50 [2]. +3 more findings

• Brain Biology

Full summary, score breakdown and related studies → Original source

Anti-amyloid immunotherapies for Alzheimer’s disease old people: eligibility and real life in a geriatric memory clinic in Lille (France)

35/100 ✓ Peer-reviewed Treatments ˜La œRevue de gériatrie

Key finding: The average age was 82.2 years, with a majority of women (68.5%). +4 more findings

• Treatments
• Clinical Trials
• Care Services

Full summary, score breakdown and related studies → Original source

Lecanemab e la malattia di Alzheimer-Perusini: tra speranze terapeutiche e sfide regolatorie

29/100 ✓ Peer-reviewed Treatments Recenti Progressi in Medicina

Key finding: The lack of effective disease-modifying treatments and its increasing prevalence in the elderly population contribute to a major burden for patients and their caregivers, challenging health systems globally. +4 more findings

• Treatments
• Brain Biology

Full summary, score breakdown and related studies → Original source

Exploring potential mechanisms of an African protective locus for Alzheimer's disease in APOEε4 carriers

40/100 ✓ Peer-reviewed Genetics Alzheimer s & Dementia

Key finding: > 0.95) and is present in all African ancestry tested. +4 more findings

• Genetics
• Prevention

Full summary, score breakdown and related studies → Original source