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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 3,051–3,075 of 27,380 studies, newest first · page 123 of 1096.

October 2025 22

  1. 2025-10-01

    Mobile App Psychoeducation for Dementia Caregivers In Vietnam: A Randomized Controlled Trial

    ✓ Peer-reviewed Caregiving Journal of Multidisciplinary Healthcare

    Key finding: A total of 172 participants were randomized. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2025-10-01

    Beyond the Primary Caregiver: A Scoping Review of Family-Centered Dementia Caregiving Programs

    ✓ Peer-reviewed Caregiving American Journal of Alzheimer s Disease & Other Dementias®

    Key finding: Most dementia caregiver programs focus on a single caregiver, overlooking diverse caregiving networks that include family, friends, and relatives who provide care. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2025-10-01

    Unmet Needs in Dementia Care: The Predictive Role of Caregiver Challenges

    ✓ Peer-reviewed Caregiving International Journal of Geriatric Psychiatry

    Key finding: A combined model incorporating predictors from both PWD and caregivers indicated that PLWD having lower education, being male, and exhibiting more neuropsychiatric symptoms are associated with more unmet needs. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2025-10-01

    Neuroimaging Compendium of Microglia, Amyloid, Tau, and Neurodegeneration Across Clinical Variants of Alzheimer Disease

    ✓ Peer-reviewed Brain scans and imaging Alzheimer Disease & Associated Disorders

    Key finding: Alzheimer disease and its clinical variants have characteristic spatial and temporal progression patterns of amyloid and tau driving symptomatology, but the distribution of microglia density, as measured by 18kDa translocator protein (TSPO) PET, is unknown. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2025-10-01

    Identifying Distinct Spatiotemporal Patterns of Juxtacortical Microstructure in Alzheimer Disease Using Diffusion MRI–derived Free Water Fraction

    ✓ Peer-reviewed Brain scans and imaging Radiology

    Key finding: Juxtacortical free water fraction, determined at diffusion MRI, was higher in participants with Alzheimer disease compared with cognitively normal controls and associated with amyloid-β, tau, and neurodegeneration biomarkers, revealing two distinct spatiotemporal progression patterns with different impacts on neuroanatomic signatures and cognitive performance.

    Full summary, score breakdown and related studies → Original source

  6. 2025-10-01

    α‐Synuclein seed amplification assay in Lewy body dementia versus Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

    Key finding: The accuracy of α-synuclein-SAA for DLB was 87% (95% confidence interval [CI]: 77% to 98%) in CSF, 85% (95% CI: 75% to 98%) in skin, 58% (95% CI: 47% to 69%) in olfactory mucosa, and 59% (95% CI: 51% to 66%) in urine. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2025-10-01

    Making time for brain health: recognising temporal inequity in dementia risk reduction

    ✓ Peer-reviewed Prevention and risk The Lancet Healthy Longevity

    Key finding: Time poverty is a measurable manifestation, denoting insufficient time for brain health, disproportionately affecting structurally disadvantaged populations and exacerbated by performance-driven cultures. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2025-10-01

    From Mandates to Mechanisms: Institutional Vulnerability, Decentralized Governance, and the Challenges of Local Disaster Risk Reduction Implementation

    ✓ Peer-reviewed Prevention and risk International Journal of Disaster Risk Science

    Key finding: The findings indicate that the deficiencies within these institutions are not merely technical but are significantly influenced by systemic disparities in power, resource allocation, and political stability. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2025-10-01

    Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

    ✓ Peer-reviewed Prevention and risk The Lancet

    Key finding: Total numbers of global DALYs grew 6·1% (95% UI 4·0-8·1), from 2·64 billion (2·46-2·86) in 2010 to 2·80 billion (2·57-3·08) in 2023, but age-standardised DALY rates, which account for population growth and ageing, decreased by 12·6% (11·0-14·1), revealing large long-term health improvements. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2025-10-01

    Zerebrale Amyloidangiopathie

    ✓ Peer-reviewed Treatments Geriatrie up2date

    Key finding: Es gibt zunehmende Evidenz für ein „prionenähnliches Verhalten“ von beta-Amyloid, was zu iatrogener CAA führen kann. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2025-10-01

    Evaluation of Polygenic Risk Scores for a Possible Genetic Basis of the Inverse Association Between Cancer and Cognitive Decline

    ✓ Peer-reviewed Genetics Alzheimer Disease & Associated Disorders

    Key finding: In UKB, PRS cancer was nominally associated with improved fluid intelligence ( β : 0.12, 95% CI: 0.01-0.22). +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2025-10-01

    APOE ε4 linked effects on clinical features and neuropathology in dementia with Lewy bodies

    ✓ Peer-reviewed Genetics Alzheimer s & Dementia

    Key finding: In analyses of APOE ε4 carriers, dosage, and genetic risk score, APOE ε4 was associated with lower odds of fluctuating cognition and parkinsonism and higher odds of visual hallucinations. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2025-10-01

    Nonalcoholic Fatty Liver Disease and Longitudinal Change in Imaging and Plasma Biomarkers of Alzheimer Disease and Vascular Pathology

    ✓ Peer-reviewed Biomarkers Carolina Digital Repository (University of North Carolina at Chapel Hill)

    Key finding: Among 1,706 participants (mean age 56 years, 62% female, 28% Black), midlife NAFLD vs no NAFLD was associated with greater late-life WMH volume (difference per SD 0.19, 95% CI 0.06-0.31) and faster late-life WMH increase over 6 years (difference in annual change, SD 0.28, 95% CI 0.05-0.51), suggesting accumulating vascular pathology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2025-10-01

    A systematic comparison of ATN biomarkers for monitoring longitudinal cognitive changes in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer s & Dementia

    Key finding: Plasma p‐tau 217 offers a cost‐effective AD‐specific alternative to tau‐PET and could potentially be implemented for monitoring cognitive changes in AD trials, while amyloid‐PET lacks utility.

    Full summary, score breakdown and related studies → Original source

  15. 2025-10-01

    Inflammatory Alterations and Multidomain Cognition in Alzheimer Disease and Related Dementias

    ✓ Peer-reviewed Biomarkers Alzheimer Disease & Associated Disorders

    Key finding: Greater TSPO is associated with lower performance in episodic memory, attention/processing speed, executive function, language, and visuospatial ability in amyloid-positive individuals, but restricted to episodic memory in amyloid-negative individuals. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2025-10-01

    Impact of Conservative Management vs. Dialysis Transition on Cognition in a National Cohort of Patients with Advanced CKD

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Society of Nephrology

    Key finding: In 18,383 CM patients PS-matched to 18,383 dialysis patients, unadjusted Cox models showed dialysis transition was associated with higher risk of dementia, MCI, or combined dementia/MCI vs. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2025-10-01

    Practical Advice for the Management of Older Adults With Inflammatory Bowel Disease

    ✓ Peer-reviewed Health systems and care delivery The American Journal of Gastroenterology

    Key finding: These include segmental colitis associated with diverticulitis, colorectal cancer, radiation proctitis, ischemic and infectious colitis, as well as NSAID-induced enterocolitis (6,7). +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2025-10-01

    Role of PCPs in diagnosing dementia in traditional Medicare and Medicare Advantage

    ✓ Peer-reviewed Health systems and care delivery Alzheimer s & Dementia

    Key finding: Among a matched sample of 15,410,030 beneficiaries, accounting for both provider and patient characteristics, the incident dementia diagnosis rate was 0.11 percentage points lower for MA beneficiaries compared to TM beneficiaries attributed to the same PCP. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2025-10-01

    Examination of metabolic syndrome in Down syndrome and association with dementia

    ✓ Peer-reviewed Down syndrome and Alzheimer's Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The prevalence of MetS was low in adults with DS. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2025-10 month only

    Efficacy and cost-effectiveness of extended nursing roles in dementia care: Results of the cluster-randomized trial InDePendent

    ✓ Peer-reviewed Costs and economics Alzheimer's & Dementia

    Key finding: The results provide evidence for the efficacy and cost-effectiveness of extended nursing roles in dementia care, demonstrating that extended nursing roles reduce unmet needs and improve quality of life. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2025-10-01

    Concurrent Changes in Plasma Phosphorylated Tau 217, Tau PET, and Cognition in Preclinical Alzheimer Disease

    ✓ Peer-reviewed Biomarkers JAMA Neurology

    Key finding: Levels of plasma p-tau217 increased significantly in Aβ+ participants before showing significant deceleration (χ2 = 21.7; P Conclusions and relevance This study found that tau PET is valuable for both prognostic and real-time tracking of disease progression. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2025-10-01

    Benzodiazepine or Antipsychotic Use and Mortality Risk Among Patients With Dementia in Hospice Care

    ✓ Peer-reviewed Treatments JAMA Network Open

    Key finding: In this national case-control study of nursing home residents with ADRD receiving hospice care, initiation of benzodiazepine or antipsychotic use was associated with increased 180-day mortality. +4 more findings

    Full summary, score breakdown and related studies → Original source

September 2025 3

  1. 2025-09-30

    miR155 triplicated in Down syndrome regulates hippocampal GABAergic neurogenesis in Alzheimer’s disease

    ⚠ Preprint — not yet peer-reviewed Down syndrome and Alzheimer's bioRxiv

    Key finding: We found that MIR155HG (miR155 host gene) colocalizes with APP (amyloid-beta precursor protein) in a neuron-specific, topologically-associated domain (TAD) within a regulatory network, in the obligate portion of chromosome 21 triplicated in DS which causes AD neuropathology and in most cases, dementia. +2 more findings

    Scored 19 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  2. 2025-09-30

    IRF1 ameliorates synaptic dysfunction through the modulation of O-GlcNAcylation on GluN1 subunit of NMDAR

    ✓ Peer-reviewed Disease mechanisms Alzheimer's research & therapy

    Key finding: In the present study, we demonstrate that Interferon Regulatory Factor-1 (IRF-1), which is deficient in the brain of individuals with Alzheimer's disease (AD), negatively regulates the O-GlcNAcylation levels of GluN1 through transcriptional regulation of the human OGA gene. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2025-09-30

    Brain Region-Specific Epigenomic Reorganization and Altered Cell States in Alzheimer's Disease

    ⚠ Preprint — not yet peer-reviewed Genetics bioRxiv : the preprint server for biology

    Key finding: Our dataset comprises over 230,000 individual cells, spanning major neuronal and glial populations, and provides a high-resolution view of multi-layer epigenomic regulation. +4 more findings

    Scored 22 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →