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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 15,026–15,050 of 27,380 studies, newest first · page 602 of 1096.

June 2017 11

  1. 2017-06-01

    Genetics of β-Amyloid Precursor Protein in Alzheimer's Disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Cold Spring Harbor perspectives in medicine

    Key finding: Together, these studies provide compelling evidence for the Aβ hypothesis and suggest that therapeutics that reduces Aβ levels or Aβ fibrillogenesis should lower the risk for or prevent AD.

    Full summary, score breakdown and related studies → Original source

  2. 2017-06-01

    Physical Activity, Brain Volume, and Dementia Risk: The Framingham Study

    ✓ Peer-reviewed Prevention trials The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Low physical activity is associated with a higher risk for dementia in older individuals, suggesting that a reduced risk of dementia and higher brain volumes may be additional health benefits of maintaining physical activity into old age. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2017-06-01

    Physical Activity and Alzheimer's Disease: A Systematic Review

    ✓ Peer-reviewed Prevention trials The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Physical activity was inversely associated with risk of AD in most studies (n = 18). +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2017-06-01

    Inflammatory Biomarkers Predict Domain-Specific Cognitive Decline in Older Adults

    ✓ Peer-reviewed Disease mechanisms The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: In particular, systemic inflammation, vascular inflammation, and altered endothelial function may play roles in domain-specific cognitive decline of nondemented individuals.

    Full summary, score breakdown and related studies → Original source

  5. 2017-06-01

    Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role

    ✓ Peer-reviewed Inflammation and the immune system Neuropathology and applied neurobiology

    Key finding: Forming non-overlapping domains, astrocytes are highly complex cells. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2017-06-01

    Why do trials for Alzheimer's disease drugs keep failing? A discontinued drug perspective for 2010-2015

    ✓ Peer-reviewed Brain tissue and pathology Expert opinion on investigational drugs

    Key finding: There are dozens of drugs in development for AD with billions of dollars invested. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2017-06-01

    EEG spectral analysis as a putative early prognostic biomarker in nondemented, amyloid positive subjects

    ✓ Peer-reviewed Mild cognitive impairment Neurobiology of aging

    Key finding: In the total sample, none of the EEG spectral measures were significant predictors. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2017-06-01

    Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice

    ✓ Peer-reviewed Caregiving Brain : a journal of neurology

    Key finding: Thus, in prion-diseased mice, both trazodone and dibenzoylmethane treatment restored memory deficits, abrogated development of neurological signs, prevented neurodegeneration and significantly prolonged survival.

    Full summary, score breakdown and related studies → Original source

  9. 2017-06-01

    Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons

    ✓ Peer-reviewed Brain scans and imaging JAMA

    Key finding: Among the 445 participants (243 with normal amyloid, 202 with elevated amyloid), mean (SD) age was 74.0 (5.9) years, mean education was 16.4 (2.7) years, and 52% were women. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2017-06-01

    Clinical presentations and epidemiology of vascular dementia

    ✓ Peer-reviewed Prevention and risk Clinical science (London, England : 1979)

    Key finding: There are two main clinical syndromes of VCI: post-stroke VCI in which cognitive impairment is the immediate consequence of a recent stroke and VCI without recent stroke in which cognitive impairment is the result of covert vascular brain injury detected only on neuroimaging or neuropathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2017-06-01

    Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: Protection from these ADP factors may be important for aging without significant ADP. +4 more findings

    Full summary, score breakdown and related studies → Original source

May 2017 14

  1. 2017-05-31

    Role of Sleep Disturbance in the Trajectory of Alzheimer's Disease

    ✓ Peer-reviewed Risk factors Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

    Key finding: We consider several factors required to exactly interpret the results and suggest a direction for future studies on the role of sleep disturbance in AD.

    Full summary, score breakdown and related studies → Original source

  2. 2017-05-31

    Anti-tau vaccine is successful in clinical trial for people with Alzheimer's disease

    ✓ Peer-reviewed Drug development Nursing older people

    Key finding: Alzheimer's disease progressively impairs cognition and daily function, and death usually occurs five to ten years after diagnosis. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2017-05-31

    Genome-wide association study of language performance in Alzheimer's disease

    ✓ Peer-reviewed Genetics Brain and language

    Key finding: To identify novel genetic variants associated with language performance, we analyzed brain MRI and performed a genome-wide association study (GWAS) using a composite measure of language performance from the Alzheimer's Disease Neuroimaging Initiative (ADNI; n=1560). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2017-05-31

    HIV-1-associated neurocognitive disorder: epidemiology, pathogenesis, diagnosis, and treatment

    ✓ Peer-reviewed Digital health tools Journal of neurology

    Key finding: The predominant clinical feature is a subcortical dementia with deficits in the domains concentration, attention, and memory. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2017-05-31

    Central adiposity and the overweight risk paradox in aging: follow-up of 130,473 UK Biobank participants

    ✓ Peer-reviewed Long-term cohort studies The American journal of clinical nutrition

    Key finding: For older groups, being overweight [body mass index (BMI; in kg/m 2 ): 25 to Objective: This study aimed to estimate associations between combined measurements of BMI and waist-to-hip ratio (WHR) with mortality and incident coronary artery disease (CAD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2017-05-30

    Omega-3 Use in Psychiatry: Evidence-Based or Elegance-Based?

    ✓ Peer-reviewed Prevention and risk Journal of dietary supplements

    Key finding: Use of omega-3 in psychiatric practice is on the rise. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2017-05-30

    Neuroprotective and Anti-Aging Potentials of Essential Oils from Aromatic and Medicinal Plants

    ✓ Peer-reviewed Costs and economics Frontiers in aging neuroscience

    Key finding: In conclusion, EOs were effective on several pathological targets and have improved cognitive performance in animal models and human subjects.

    Full summary, score breakdown and related studies → Original source

  8. 2017-05-30

    Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

    ✓ Peer-reviewed Clinical safety The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Here, we found that activated astrocytes in the 5xFAD mouse model were strongly associated with proteolysis of the protein phosphatase calcineurin (CN) and the elevated expression of the CN-dependent transcription factor nuclear factor of activated T cells 4 (NFAT4). +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2017-05-30

    The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism

    ✓ Peer-reviewed TREM2 and immune genetics The EMBO journal

    Key finding: Homozygous TREM2 missense mutations, such as p.T66M, lead to the FTD-like syndrome, but how they cause pathology is unknown. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2017-05-30

    C-terminal fragments of the amyloid precursor protein in cerebrospinal fluid as potential biomarkers for Alzheimer disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Scientific reports

    Key finding: The CSF level of this 25-kDa CTF is higher in subjects with autosomal dominant AD linked to PSEN1 mutations, in demented Down syndrome individuals and in sporadic AD subjects compared to age-matched controls. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2017-05-27

    Advanced Glycation End-Products Are Associated With the Presence and Severity of Paratonia in Early Stage Alzheimer Disease

    ✓ Peer-reviewed Disease mechanisms Journal of the American Medical Directors Association

    Key finding: From the 144 participants (56.3% female and 43.7% male, with a mean [standard deviation] age of 80.7 [7.7] years), 118 participants were available for final follow-up. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2017-05-26

    Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurodegeneration

    Key finding: The majority of drugs developed for AD focus on the amyloid cascade hypothesis, which implicates Aß plaques as a causal factor in the disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2017-05-25

    Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels

    ✓ Peer-reviewed Disease mechanisms Scientific reports

    Key finding: Their cognitive decline was decreased compared with controls, due to a reduction in brain damage and reduced accumulation of amyloid beta aggregates. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2017-05-25

    Cognitive Testing in People at Increased Risk of Dementia Using a Smartphone App: The iVitality Proof-of-Principle Study

    ✓ Peer-reviewed Cognitive tests and assessment JMIR mHealth and uHealth

    Key finding: Repeated smartphone-assisted cognitive testing is feasible with reasonable adherence and moderate relative validity for the Stroop and the Trail Making tests compared with conventional neuropsychological tests. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →