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Clinical presentations and epidemiology of vascular dementia
Smith EE.. Clinical science (London, England : 1979), 2017-06-01
Topic: Risk, prevention and care in population studies
Cerebrovascular and cardiovascular diseases cause vascular brain injury that can lead to vascular cognitive impairment (VCI). VCI is the second most common neuropathology of dementia and mild cognitive impairment (MCI), accounting for up to one-third of the population risk. It is frequently present along with other age-related pathologies such as Alzheimer's disease (AD). Multiple etiology dementia with both VCI and AD is the single most common cause of later life dementia. There are two main clinical syndromes of VCI: post-stroke VCI in which cognitive impairment is the immediate consequence of a recent stroke and VCI without recent stroke in which cognitive impairment is the result of covert vascular brain injury detected only on neuroimaging or neuropathology. VCI is a syndrome that can result from any cause of infarction, hemorrhage, large artery disease, cardioembolism, small vessel disease, or other cerebrovascular or cardiovascular diseases. Secondary prevention of further vascular brain injury may improve outcomes in VCI.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Smith, E. E. (2017). Clinical presentations and epidemiology of vascular dementia. Clinical science (London, England : 1979). https://doi.org/10.1042/cs20160607
Vancouver
Smith EE. Clinical presentations and epidemiology of vascular dementia. Clinical science (London, England : 1979). 2017. doi:10.1042/cs20160607. PMID: 28515342.
BibTeX
@article{smith2017-28515342,
author = {Smith, E. E.},
title = {{Clinical presentations and epidemiology of vascular dementia}},
journal = {Clinical science (London, England : 1979)},
year = {2017},
doi = {10.1042/cs20160607},
pmid = {28515342},
url = {https://doi.org/10.1042/cs20160607}
}
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Key findings
- There are two main clinical syndromes of VCI: post-stroke VCI in which cognitive impairment is the immediate consequence of a recent stroke and VCI without recent stroke in which cognitive impairment is the result of covert vascular brain injury detected only on neuroimaging or neuropathology.
- VCI is a syndrome that can result from any cause of infarction, hemorrhage, large artery disease, cardioembolism, small vessel disease, or other cerebrovascular or cardiovascular diseases.
Why it matters
This review describes vascular cognitive impairment as the second most common neuropathology of dementia and mild cognitive impairment, often occurring alongside Alzheimer's disease. It notes that secondary prevention of further vascular brain injury may improve outcomes, but it does not show a cure or proven prevention for Alzheimer's disease.
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Study details
- Evidence strengthLow
How this study scored 47/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomized / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Clinical science (London, England : 1979)) |
| Journal's citation record | 2 / 4 | Clinical Science: journal h-index 212 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2017 — within 10 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 249 times (OpenAlex, 2026-10-10) |
| Citations per year | 4 / 5 | 22.6 citations a year over 11 year(s) since 2017 |
| Impact for its field and year | 5 / 6 | Cited 21.2× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 5 other studies in this library |
| Still being cited | 2 / 4 | Cited 42 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Eric Edward Smith: h-index 127 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | University of Calgary: institution h-index 1,028 (OpenAlex) |
| Multicenter collaboration | 0 / 3 | OpenAlex lists 1 institution(s) in 1 country — scores zero (affiliation lists can be incomplete) |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 28515342) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 47 / 100 | — |
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