Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 27,151–27,175 of 27,380 studies, newest first · page 1087 of 1096.
July 1988 5
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1988-07-01
Nervous system complications in uremia
40/100 ✓ Peer-reviewed Clinical safety Annals of internal medicine
Key finding: Dialysis itself is associated with at least three distinct disorders of the central nervous system, including the dialysis disequilibrium syndrome, dialysis dementia, and progressive intellectual dysfunction. +1 more finding
Full summary, score breakdown and related studies → Original source
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1988-07-01
Posterior cortical atrophy
41/100 ✓ Peer-reviewed Brain tissue and pathology Archives of neurology
Key finding: Predominant parieto-occipital atrophy was demonstrated on both computed tomography and magnetic resonance imaging in two of the patients; posterior circulation was normal by angiography in the three studied.
Full summary, score breakdown and related studies → Original source
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1988-07-01
Alzheimer's disease. A double-labeling immunohistochemical study of senile plaques
41/100 ✓ Peer-reviewed Inflammation and the immune system The American journal of pathology
Key finding: The histopathology of senile plaques was studied using double-labeling immunohistochemistry and lectin histochemistry with thioflavin S fluorescent microscopy in 9 cases of Alzheimer's disease, 2 nondemented elderly individuals, and 3 individuals with non-Alzheimer primary degenerative dementias. +3 more findings
Full summary, score breakdown and related studies → Original source
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1988-07-01
Digital and palmar dermatoglyphics in dementia of the Alzheimer type
32/100 ✓ Peer-reviewed Down syndrome and Alzheimer's American journal of medical genetics
Key finding: Female patients had significantly (p less than 0.05) more accessory triradii and complete Sydney creases than controls; no dermatoglyphic differences were detected in the males.
Full summary, score breakdown and related studies → Original source
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1988-07-01
A characterization of the prosodic loss in Parkinson's disease
39/100 ✓ Peer-reviewed Digital health tools Brain and language
Key finding: Prosodic contours in the verbal output of 30 patients with Idiopathic Parkinson's disease were contrasted to those of fifteen age-, sex-, and educationally matched normal subjects. +3 more findings
Full summary, score breakdown and related studies → Original source
June 1988 7
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1988-06-01
Immunochemical and biochemical characterization of tau proteins in normal and Alzheimer's disease brains with Alz 50 and Tau-1
36/100 ✓ Peer-reviewed Drug development The Journal of biological chemistry
Key finding: Quantitative analysis of immunoblots with the antibodies showed that both homogenate and supernatant fractions (12,000 x g) from Alzheimer brains contained 38-65% less tau immunoreactivity compared to normal brains. +2 more findings
Full summary, score breakdown and related studies → Original source
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1988-06-01
Acute confusional states in elderly patients treated for femoral neck fracture
36/100 ✓ Peer-reviewed Vascular contributions Journal of the American Geriatrics Society
Key finding: Drugs with anticholinergic effect, depression, and previous stroke were factors that seemed to be associated with the development of ACS. +1 more finding
Full summary, score breakdown and related studies → Original source
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1988-06-01
Screening for dementia by memory testing
47/100 ✓ Peer-reviewed Cognitive tests and assessment Neurology
Enhanced cued recall provides a simple and clinically useful memory test for identifying dementia in the elderly.
Full summary, score breakdown and related studies → Original source
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1988-06-01
Usefulness of mortality data in determining the geography and time trends of dementia
39/100 ✓ Peer-reviewed Risk factors Journal of Epidemiology & Community Health
Key finding: Analysis of all certified deaths from dementia during 1968-78 by place of residence shows that areas with a significantly high SMR usually contain a large psychiatric hospital.
Full summary, score breakdown and related studies → Original source
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1988-06-01
The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease
56/100 ✓ Peer-reviewed Lewy body dementia Journal of neurology, neurosurgery, and psychiatry
Key finding: Associated pathological findings suggest that these cases of incidental Lewy body disease are presymptomatic cases of Parkinson's disease, and confirm the importance of age (time) in the evolution of the disease.
Full summary, score breakdown and related studies → Original source
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1988-06-01
Thalamic infarcts: clinical syndromes, etiology, and prognosis
48/100 ✓ Peer-reviewed Risk factors Neurology
Key finding: We found no risk factor other than age or oral contraceptive use in six patients.
Full summary, score breakdown and related studies → Original source
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1988-06-01
Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis
55/100 ✓ Peer-reviewed Getting a diagnosis The New England journal of medicine
Key finding: Among 141 consecutive patients with neuro-psychiatric abnormalities due to cobalamin deficiency, we found that 40 (28 percent) had no anemia or macrocytosis. +1 more finding
Full summary, score breakdown and related studies → Original source
May 1988 3
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1988-05-01
The pathological association between Down syndrome and Alzheimer disease
44/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Mechanisms of ageing and development
Key finding: The neuropathology of Down syndrome (DS) at middle age is compared with that of Alzheimer disease (AD) at that age, through a review of the published literature and from the author's personal observations on brains from a series of patients of different ages with DS. +1 more finding
Full summary, score breakdown and related studies → Original source
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1988-05-01
Alzheimer's disease and Parkinson's disease: comparison of speech and language alterations
48/100 ✓ Peer-reviewed Digital health tools Neurology
Key finding: DAT produced significantly greater language disturbances, including anomia, decreased information content of spontaneous speech, and diminished word list generation. +2 more findings
Full summary, score breakdown and related studies → Original source
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1988-05-01
Black-white differences in psychopathology in an urban psychiatric population
35/100 ✓ Peer-reviewed Disparities Comprehensive psychiatry
Key finding: Some differences appeared to be due to selection factors and others raised the question of alternate expressions of psychopathology among blacks as versus whites. +1 more finding
Full summary, score breakdown and related studies → Original source
April 1988 2
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1988-04-29
Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology
57/100 ✓ Peer-reviewed Genetics Science
Apolipoprotein E is a plasma protein that serves as a ligand for low density lipoprotein receptors and, through its interaction with these receptors, participates in the transport of cholesterol and other lipids among various cells of the body.
Full summary, score breakdown and related studies → Original source
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1988-04 month only
No response to high-dose muscarinic agonist therapy in Alzheimer's disease
48/100 ✓ Peer-reviewed Clinical trials Neurology
Key finding: No consistent, clinically significant cognitive improvement could be discerned in these mild to moderately demented patients, despite attainment of central RS-86 levels approximating those that affect behavior in the experimental animal.
Full summary, score breakdown and related studies → Original source
March 1988 4
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1988-03-01
Stroke: Pathophysiology, Diagnosis, and Management
38/100 ✓ Peer-reviewed Vascular contributions Annals of Internal Medicine
Key finding: Platelet Function and Antiplatelet Agents. +4 more findings
Full summary, score breakdown and related studies → Original source
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1988-03-01
Dementia of frontal lobe type
45/100 ✓ Peer-reviewed Digital health tools Journal of neurology, neurosurgery, and psychiatry
Key finding: A significant proportion of patients with presenile dementia due to primary cerebral atrophy do not have Alzheimer's disease. +2 more findings
Full summary, score breakdown and related studies → Original source
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1988-03-01
Preparation of a recombinant cDNA library from poly(A+) RNA of the Alzheimer brain. Identification and characterization of a cDNA copy encoding a glial-specific protein
33/100 ✓ Peer-reviewed Biomarkers Neurobiology of aging
Key finding: These results agree with earlier studies on GFAP mRNA from fresh mouse brain. +1 more finding
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1988-03-01
The postmortem Alzheimer brain is a source of structurally and functionally intact astrocytic messenger RNA
36/100 ✓ Peer-reviewed Biomarkers Journal of neuroscience methods
Key finding: Relative to controls, AD mRNA synthesized a two-fold higher level of a 50,000 mol.wt. protein that was immunologically identified as GFAP. +4 more findings
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February 1988 4
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1988-02-01
Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease
36/100 ✓ Peer-reviewed Treatments Cell
Key finding: DNA sequence analysis showed that these clones code for alpha 1-antichymotrypsin.
Full summary, score breakdown and related studies → Original source
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1988-02-01
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1988-02-01
Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques
52/100 ✓ Peer-reviewed Brain tissue and pathology Annals of Neurology
Postmortem examination was performed on 137 residents (average age 85.5 years) of a skilled nursing facility whose mental status, memory, and functional status had been evaluated during life.
Full summary, score breakdown and related studies → Original source
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1988-02-01
Cornell scale for depression in dementia
48/100 ✓ Peer-reviewed Cognitive tests and assessment Biological Psychiatry
The Cornell Scale for Depression in Dementia is introduced.
Full summary, score breakdown and related studies → Original source
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