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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 26,026–26,050 of 27,380 studies, newest first · page 1042 of 1096.

January 1998 21

  1. 1998-01-01

    Nitric oxide in neurodegeneration

    ✓ Peer-reviewed Vascular contributions Progress in brain research

    Key finding: NO plays a role in mediating neurotoxicity associated with a variety of neurologic disorders, including stroke, Parkinson's Disease, and HIV dementia.

    Full summary, score breakdown and related studies → Original source

  2. 1998-01-01

    Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis

    ✓ Peer-reviewed Disease mechanisms Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: The hypothesis is forwarded that sporadic late-onset Alzheimer disease is caused by non-insulin dependent diabetes mellitus which is confined to the brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1998 no date recorded — placed by publication year

    A nonparametric method for automatic correction of intensity nonuniformity in MRI data

    ✓ Peer-reviewed Brain scans and imaging IEEE Transactions on Medical Imaging

    A novel approach to correcting for intensity nonuniformity in magnetic resonance (MR) data is described that achieves high performance without requiring a model of the tissue classes present.

    Full summary, score breakdown and related studies → Original source

  4. 1998-01-01

    Alzheimer's disease--synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts

    ✓ Peer-reviewed Inflammation and the immune system Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: However, there is increasing evidence that the previously so-called "secondary factors" such as a disturbed glucose metabolism, oxidative stress and formation of "advanced glycation endproducts" (AGEs) and their interaction in a vicious cycle are also important for the onset and progression of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1998-01-01

    Mutant genes in familial Alzheimer's disease and transgenic models

    ✓ Peer-reviewed Brain tissue and pathology Annual review of neuroscience

    Key finding: Some cases of AD, particularly those of early onset, are familial and inherited as autosomal dominant disorders linked to the presence of mutant genes that encode the amyloid precursor protein (APP) or the presenilins (PS1 or PS2). +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1998-01-01

    A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Donepezil Study Group

    ✓ Peer-reviewed Treatments Neurology

    Key finding: Patients were randomly assigned to treatment with placebo (n = 162), 5 mg/d donepezil (n = 154), or 10 mg/d donepezil (n = 157) for 24 weeks followed by a 6-week, single-blind placebo washout. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1998-01-01

    The progression of the lesions in Alzheimer disease: insights from a prospective clinicopathological study

    ✓ Peer-reviewed Drug development Journal of neural transmission. Supplementum

    Key finding: They are also found in old patients who have been considered to be intellectually normal throughout their life, a situation referred to as "physiological aging". +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1998-01-01

    Estimation of the genetic contribution of presenilin-1 and -2 mutations in a population-based study of presenile Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Human molecular genetics

    Key finding: We performed a systematic mutation analysis of all coding and 5'-non-coding exons of PS -1 and PS -2 in a population-based epidemiological series of 101 unrelated familial and sporadic presenile AD cases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1998-01-01

    Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

    ✓ Peer-reviewed Risk genes beyond APOE Nature medicine

    Key finding: The mutant APP(K670N,M671L) transgenic line, Tg2576, shows markedly elevated amyloid beta-protein (A beta) levels at an early age and, by 9-12 months, develops extracellular AD-type A beta deposits in the cortex and hippocampus. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1998-01-01

    Apathy is not depression

    ✓ Peer-reviewed Lewy body dementia The Journal of neuropsychiatry and clinical neurosciences

    Key finding: If depression is associated with apathy, then they should be expressed together in different dementia syndromes and should co-occur at varying levels of disease severity.

    Full summary, score breakdown and related studies → Original source

  11. 1998-01-01

    Tubulin immunopositive structures resembling intracellular neurofibrillary tangles

    ✓ Peer-reviewed Down syndrome and Alzheimer's Neurobiology of aging

    Key finding: We found beta-tubulin immunoreactive NFT-like structures in Alzheimer disease, and, more frequently, in the parkinsonism dementia complex of Guam (bodig disease) and Down Syndrome.

    Full summary, score breakdown and related studies → Original source

  12. 1998-01-01

    Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype

    ✓ Peer-reviewed Risk factors Neurology

    Key finding: Patients with Alzheimer's disease (AD) have elevations of fasting plasma insulin that are hypothesized to be associated with disrupted brain insulin metabolism. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 1998-01-01

    Cerebellar degeneration associated with human immunodeficiency virus infection

    ✓ Peer-reviewed Digital health tools Neurology

    Key finding: Cerebellar disorders associated with HIV infection are typically the result of discrete cerebellar lesions resulting from opportunistic infections such as toxoplasmosis and progressive multifocal leukoencephalopathy or primary CNS lymphoma. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 1998-01-01

    Critical appraisal of the health research literature: prevalence or incidence of a health problem

    ✓ Peer-reviewed How common it is Chronic diseases in Canada

    Key finding: The criteria relate to the validity of the study methods (design, sampling frame, sample size, outcome measures, measurement and response rate), interpretation of the results and applicability of the findings.

    Full summary, score breakdown and related studies → Original source

  15. 1998-01-01

    Effects of literacy and education on measures of word fluency

    ✓ Peer-reviewed Disparities Brain and language

    Key finding: Analysis of variance revealed main effects of education and task with a task by education interaction such that education had a greater effect on initial sound fluency than on category fluency. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 1998-01-01

    The Bayer Activities of Daily Living Scale (B-ADL)

    ✓ Peer-reviewed Caregiving Dementia and geriatric cognitive disorders

    Key finding: Statistical, clinical and domain-related criteria were used to select items from among a large number of activities of daily living (ADL) questions field tested in pilot studies in the USA, Germany, UK, Russia and Greece. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 1998-01-01

    Diagnosis of intracranial vasculitis: a multi-disciplinary approach

    ✓ Peer-reviewed Brain scans and imaging Journal of neuropathology and experimental neurology

    Key finding: Nine patients demonstrated granulomatous or lymphocytic vasculitis, 1 had lymphocytic vasculitis and encephalitis secondary to arbovirus infection, 5 had thickened vessels consistent with hypertensive changes, 5 had amyloid angiopathy and/or changes of Alzheimer disease, 5 demonstrated no pathologic abnormalities, and 1 each had acute infarct, vascular malformation, aneurysm, acellular fibrinoid necrosis, and demyelination. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 1998-01-01

    Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease

    ✓ Peer-reviewed Getting a diagnosis Annals of neurology

    Key finding: False-positive results in a single CSF analysis were seen in patients with herpes simplex encephalitis, hypoxic brain damage, atypical encephalitis, intracerebral metastases of a bronchial carcinoma, metabolic encephalopathy, and progressive dementia of unknown cause.

    Full summary, score breakdown and related studies → Original source

  19. 1998-01-01

    Propentofylline in the treatment of vascular dementia and Alzheimer-type dementia: overview of phase I and phase II clinical trials

    ✓ Peer-reviewed Treatments Alzheimer disease and associated disorders

    Key finding: These studies have shown that PPF 300 mg t.i.d. is safe and well tolerated when taken on an empty stomach 1 h before meals. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 1998-01-01

    Run-in periods in randomized trials: implications for the application of results in clinical practice

    ✓ Peer-reviewed Treatments JAMA

    Key finding: Prerandomization run-in periods are being used to select or exclude patients in an increasing number of clinical trials, but the implications of run-in periods for interpreting the results of clinical trials and applying these results in clinical practice have not been systematically examined. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 1998-01-01

    Hepatocyte growth factor (HGF/SF) in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Brain research

    Key finding: In a previous study, we showed that basic fibroblast growth factor (bFGF), another heparin-binding protein is increased in Alzheimer's disease (AD), and appears to be associated with the heparan-sulfate proteoglycans bound to B/A4 amyloid (Biochem. +3 more findings

    Full summary, score breakdown and related studies → Original source

December 1997 4

  1. 1997-12-01

    Mutations in the transmembrane domain of APP altering gamma-secretase specificity

    ✓ Peer-reviewed Biomarkers Biochemistry

    Key finding: We observed that all Thr43 mutations altered the specificity of gamma-secretase. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1997-12-01

    Neuropathological assessment of the lesions of significance in vascular dementia

    ✓ Peer-reviewed Vascular contributions Journal of neurology, neurosurgery, and psychiatry

    Key finding: Microvascular disease, not macroscopic infarction, was the chief substrate of vascular dementia in this series of cases. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1997-12-01

    Community-acquired pneumonia in the elderly. Clinical and nutritional aspects

    ✓ Peer-reviewed Clinical safety American journal of respiratory and critical care medicine

    Key finding: Nutritional aspects and the mental status of patients with pneumonia were compared with those of a control population (n = 101) matched for gender, age, and date of hospitalization. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1997-12-01

    Clinical Dementia Rating: A Reliable and Valid Diagnostic and Staging Measure for Dementia of the Alzheimer Type

    ✓ Peer-reviewed Cognitive tests and assessment International Psychogeriatrics

    Global staging measures for dementia of the Alzheimer type (DAT) assess the influence of cognitive loss on the ability to conduct everyday activities and represent the "ultimate test" of efficacy for antidementia drug trials.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →