Home › Research › Inflammation and the immune system
The potential mechanism of postoperative cognitive dysfunction in older people
Lin X, Chen Y, Zhang P, Chen G, Zhou Y, Yu X.. Experimental gerontology, 2019-11-23
Topic: Risk, prevention and care in population studies
Postoperative cognitive dysfunction (POCD) is a common disorder following surgery, which seriously threatens the quality of patients' life, especially the older people. Accumulating attention has been paid to POCD worldwide in pace with the popularization of anesthesia/surgery. The development of medical humanities and rehabilitation medicine sets higher demands on accurate diagnosis and safe treatment system of POCD.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Lin, X., Chen, Y., Zhang, P., Chen, G., Zhou, Y., & Yu, X. (2020). The potential mechanism of postoperative cognitive dysfunction in older people. Experimental gerontology. https://doi.org/10.1016/j.exger.2019.110791
Vancouver
Lin X, Chen Y, Zhang P, Chen G, Zhou Y, Yu X. The potential mechanism of postoperative cognitive dysfunction in older people. Experimental gerontology. 2020. doi:10.1016/j.exger.2019.110791. PMID: 31765741.
BibTeX
@article{lin2020-31765741,
author = {Lin, X. and Chen, Y. and Zhang, P. and Chen, G. and Zhou, Y. and Yu, X.},
title = {{The potential mechanism of postoperative cognitive dysfunction in older people}},
journal = {Experimental gerontology},
year = {2020},
doi = {10.1016/j.exger.2019.110791},
pmid = {31765741},
url = {https://doi.org/10.1016/j.exger.2019.110791}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- Accumulating attention has been paid to POCD worldwide in pace with the popularization of anesthesia/surgery.
- The development of medical humanities and rehabilitation medicine sets higher demands on accurate diagnosis and safe treatment system of POCD.
- Although the research on POCD is in full swing, underlying pathogenesis is still inconclusive due to these conflicting results and controversial evidence.
- Generally, POCD is closely related to neuropsychiatric diseases such as dementia, depression and Alzheimer's disease in molecular pathways.
Why it matters
This review states that the underlying cause of postoperative cognitive dysfunction remains inconclusive because of conflicting results and controversial evidence. It notes a link between POCD and conditions such as dementia, but offers no treatment or cure.
Study details
- Evidence strengthLow
How this study scored 45/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Experimental gerontology) |
| Journal's citation record | 2 / 4 | Experimental Gerontology: journal h-index 195 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2020 — within 10 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 6 / 7 | Cited 323 times (OpenAlex, 2026-10-10) |
| Citations per year | 4 / 5 | 40.4 citations a year over 8 year(s) since 2020 |
| Impact for its field and year | 3 / 6 | Cited 7.4× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 1 / 6 | Cited by 1 other studies in this library |
| Still being cited | 3 / 4 | Cited 175 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Xin Yu: h-index 35 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Zhejiang University: institution h-index 1,040 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 31765741) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 45 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/j.exger.2019.110791
- PubMed: 31765741
- Original source →
- Free full text: Experimental Gerontology →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Studies this one cites
Referenced by this study and also in the alzhub library, so you can read them here.
Later studies that cite this one
1 study in the alzhub library lists this one in its references.
Related studies in Inflammation and the immune system
Also tagged “cognitive-function”
1,118 studies in the library carry the topic tag “cognitive-function”; these are this study's neighbours in a fixed, alphabetical-by-hash tour of them, not the closest in content. All 1,118 tagged studies.