Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 11,426–11,450 of 27,380 studies, newest first · page 458 of 1096.
July 2020 25
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2020-07-15
The Mediterranean diet and menopausal health: An EMAS position statement
45/100 ✓ Peer-reviewed Prevention trials Maturitas
Key finding: Globally, 985 million women are aged 50 and over, leading to increasing concerns about chronic conditions such as cardiovascular disease, osteoporosis, dementia, and cognitive decline, which can adversely affect quality of life and independent living. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-15
Cardiovascular risk factors and accelerated cognitive decline in midlife: The CARDIA Study
59/100 ✓ Peer-reviewed Disparities Neurology
Key finding: Midlife CVRFs, especially hypertension, diabetes mellitus, and smoking, are common and associated with accelerated cognitive decline at midlife. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-14
Pain Management in Home Health Care: Relationship With Dementia and Facility Admissions
55/100 ✓ Peer-reviewed Costs and economics Pain management nursing : official journal of the American Society of Pain Management Nurses
Key finding: Patients with ADRD (n = 1,525, 24.8%) were less likely to have recorded severe pain than others (16.4% vs. 23.6%, p < .001). +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-14
Health Impacts from Ambient Particle Exposure in Southern Sweden
68/100 ✓ Peer-reviewed Risk factors International journal of environmental research and public health
Key finding: Locally produced PM2.5 alone contributed to 2-9% of the cases of diseases and disorders investigated. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-14
Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer's disease: a longitudinal cohort study
71/100 ✓ Peer-reviewed Biomarkers Molecular psychiatry
Key finding: Compared with non-carriers, plasma p-tau181 concentration was higher in both symptomatic (p < 0.001) and presymptomatic mutation carriers (p < 0.001).
Full summary, score breakdown and related studies → Original source
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2020-07-14
Education Research: Online Alzheimer education for high school and college students: A randomized controlled trial
64/100 ✓ Peer-reviewed Treatments Neurology
Key finding: Online education involving a celebrity may be an effective strategy for educating college students about AD risk reduction strategies.
Full summary, score breakdown and related studies → Original source
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2020-07-13
Sleep characteristics and cerebrospinal fluid biomarkers of Alzheimer's disease pathology in cognitively intact older adults: The CABLE study
43/100 ✓ Peer-reviewed Tau biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: Greater daytime sleepiness was associated with higher CSF indicators of amyloid deposition in female patients. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-13
Endothelium-Macrophage Crosstalk Mediates Blood-Brain Barrier Dysfunction in Hypertension
38/100 ✓ Peer-reviewed Vascular contributions Hypertension (Dallas, Tex. : 1979)
Key finding: Perivascular macrophages (PVM), innate immune cells closely associated with cerebral microvessels, have emerged as major contributors to neurovascular dysfunction. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-13
Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia
58/100 ✓ Peer-reviewed TREM2 and immune genetics The EMBO journal
Key finding: Microglia, through the elimination of supernumerary synapses, have an established role in this process. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-13
Association of cerebrovascular reactivity and Alzheimer pathologic markers with cognitive performance
59/100 ✓ Peer-reviewed Brain scans and imaging Neurology
Key finding: CVR was significantly associated with cognitive performance independently of AD pathology. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-11
MicroRNAs Related to Cognitive Impairment After Hearing Loss
41/100 ✓ Peer-reviewed Risk factors Clinical and experimental otorhinolaryngology
Key finding: The deaf group showed considerably lower scores on the OPT, OLT, and Y-maze test than the control group. +2 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-11
The presence of a caregiver is associated with patient outcomes in patients with Parkinson's disease and atypical parkinsonisms
61/100 ✓ Peer-reviewed Treatments Parkinsonism & related disorders
Key finding: These findings have implications for clinical practice and suggest that presence of a caregiver may be an important modifying variable on patient outcomes to examine in future research. +2 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-10
Endosomal-lysosomal dysfunction in metabolic diseases and Alzheimer's disease
39/100 ✓ Peer-reviewed Disease mechanisms International review of neurobiology
Key finding: Many genetic mutations and risk factor genes associated with proteinopathies, as well as with metabolic diseases like diabetes, negatively influence endocytic trafficking and autophagic clearance.
Full summary, score breakdown and related studies → Original source
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2020-07-10
Longitudinal validity of PET-based staging of regional amyloid deposition
59/100 ✓ Peer-reviewed Brain scans and imaging Human brain mapping
Key finding: Positron emission tomography (PET)-based staging of regional amyloid deposition has recently emerged as a promising tool for sensitive detection and stratification of pathology progression in Alzheimer's Disease (AD). +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-07-10
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain
53/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Molecular psychiatry
Key finding: We found that T21 organoids secrete increased proportions of Aβ-preventing (Aβ1-19) and Aβ-degradation products (Aβ1-20 and Aβ1-34).
Full summary, score breakdown and related studies → Original source
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2020-07-09
Competing crises: COVID‐19 countermeasures and social isolation among older adults in long‐term care
41/100 ✓ Peer-reviewed End-of-life care Journal of Advanced Nursing
Key finding: This suggests that if physical distancing measures are extended for months or years until either herd immunity or a vaccination, a shocking proportion of LTC residents are likely to die under a 'new normal' of isolation that few would choose. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-09
The Association Between Early Age-Related Hearing Loss and Brain β-Amyloid
64/100 ✓ Peer-reviewed Risk factors The Laryngoscope
Key finding: The mean age ± standard deviation was 64.6 ± 3.5 years. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-09
18F-SMBT-1: A Selective and Reversible PET Tracer for Monoamine Oxidase-B Imaging
44/100 ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Key finding: In vitro binding assays demonstrated a high binding affinity of 18 F-SMBT-1 to MAO-B (dissociation constant, 3.7 nM). +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-08
Corticomotor Plasticity Predicts Clinical Efficacy of Combined Neuromodulation and Cognitive Training in Alzheimer's Disease
57/100 ✓ Peer-reviewed Cognitive tests and assessment Frontiers in aging neuroscience
Key finding: Combined rTMS and cognitive training may improve the cognitive status of AD patients, with TMS-induced cortical plasticity at baseline serving as predictor of therapeutic outcome for this intervention, and potential mechanism of action. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-07-08
Functional Near-Infrared Spectroscopy in the Study of Speech and Language Impairment Across the Life Span: A Systematic Review
53/100 ✓ Peer-reviewed Digital health tools American journal of speech-language pathology
Key finding: Though it is not without inherent challenges, fNIRS may have advantages over other neuroimaging techniques in the areas of speech and language impairment. fNIRS has clinical applications that may lead to improved early and differential diagnosis, increase our understanding of response to treatment, improve neuroprosthetic functioning, and advance neurofeedback.
Full summary, score breakdown and related studies → Original source
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2020-07-07
A Seat at the Table: Supporting Persons with Severe Dementia in Communicating Their Preferences
48/100 ✓ Peer-reviewed Health systems and care delivery Clinical gerontologist
Key finding: Neither assessment condition promoted significantly greater levels of consistency (i.e., the same preference rating at Time 1 and Time 2). +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-07
Environmental exposure to phthalates and dementia with Lewy bodies: contribution of metabolomics
50/100 ✓ Peer-reviewed Risk factors Journal of neurology, neurosurgery, and psychiatry
Key finding: Among the compounds detected in greater abundance in the CSF of patients with DLB compared with patients with AD, only one had a xenobiotic profile potentially related to the pathophysiology of DLB. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-07
Dual sensory impairment in older adults and risk of dementia from the GEM Study
59/100 ✓ Peer-reviewed Risk factors Alzheimer's & dementia (Amsterdam, Netherlands)
Key finding: DSI was significantly associated with higher risk of all-cause dementia (hazard ratio [HR] = 1.86; 95% confidence interval [CI] = 1.25-2.76) and Alzheimer's disease (HR = 2.12; 95% CI = 1.34-3.36). +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-07
The socio-economic determinants of COVID-19: A spatial analysis of German county level data
33/100 ✓ Peer-reviewed Risk factors Not indexed
Key finding: The case and death rates are, for example, significantly positively associated with early cases from the beginning of the epidemic, the average age, the population density and the number of people employed in elderly care. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-07-07
TREM2 ectodomain and its soluble form in Alzheimer's disease
45/100 ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroinflammation
Key finding: It mediates multiple pathophysiological processes in various diseases. +3 more findings
Full summary, score breakdown and related studies → Original source
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