Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 9,401–9,425 of 27,380 studies, newest first · page 377 of 1096.

January 2022 25

  1. 2022 year only

    Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease

    ✓ Peer-reviewed Genetics Journal of Alzheimer's disease : JAD

    Key finding: ADVP V1.0 (February 2021) catalogs 6,990 associations related to disease-risk, expression quantitative traits, endophenotypes, or neuropathology. +4 more findings

  2. 2022 year only

    Effects of ApoE4 and ApoE2 genotypes on subcortical magnetic susceptibility and microstructure in 27,535 participants from the UK Biobank

    ✓ Peer-reviewed Genetics Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing

    Key finding: Disrupted iron homeostasis is associated with several neurodegenerative diseases, including Alzheimer's disease (AD), and may be partially modulated by genetic risk factors. +3 more findings

  3. 2022 year only

    Isoform-Dependent Effects of Apolipoprotein E on Sphingolipid Metabolism in Neural Cells

    ✓ Peer-reviewed Genetics Journal of Alzheimer's disease : JAD

    Key finding: In the brains of Apoeshl mice, the levels of apoM were lower, while those of ceramides were higher. +4 more findings

  4. 2022 year only

    Validity of the Web-Based, Self-Directed, NeuroCognitive Performance Test in Mild Cognitive Impairment

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: In MCI subjects, the NCPT composite is significantly correlated with both a composite measure of established tests (r = 0.78, p < 0.0001) as well as with the ADAS-Cog (r = -0.55, p < 0.0001). +4 more findings

  5. 2022 year only

    Digital Intervention for the Management of Alzheimer's Disease

    ✓ Peer-reviewed Cognitive tests and assessment Current Alzheimer research

    Key finding: Dtx provides evidence based therapeutic interventions driven by internet and software, employing tools such as mobile devices, computers, videogames, apps, sensors, virtual reality aiding in the prevention, management, and treatment of ailments like neurological abnormalities and chronic diseases. +4 more findings

  6. 2022 year only

    The Use of Digital Technology to Assess Cognitive Function in Tunisian Adults

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: The AD group performed significantly lower on the associative learning (p = 0.01) and associative memory assessments (p = 0.002), than the HC and AR groups. +4 more findings

  7. 2022 year only

    Characteristics of Drawing Process Differentiate Alzheimer's Disease and Dementia with Lewy Bodies

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: Reduced speed and reduced smoothness in speed and pressure were observed particularly in the LBD group, while increased pauses and total durations were observed in both the AD and LBD groups. +2 more findings

  8. 2022 year only

    Distinct Patterns Link the BDNF Val66Met Polymorphism to Alzheimer's Disease Pathology

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: We found distinct pathways to Alzheimer's disease pathology: Val-Met displayed lower CSF-Aβ42 in APOE ɛ4+ carriers, independent of p-tau, while Val-Val displayed greater p-tau at higher IL-6 and sub-threshold Aβ42.

  9. 2022 year only

    Elecsys Cerebrospinal Fluid Assays Accurately Distinguish Alzheimer's Disease from Frontotemporal Lobar Degeneration

    ✓ Peer-reviewed Tau biomarkers The journal of prevention of Alzheimer's disease

    Key finding: AUC-based performance was similarly good for the pTau181/Aβ42 ratio (AUC=0.841; 95% CI: 0.759-0.923), pTau181/Aβ40 ratio (AUC=0.837; 95% CI: 0.754-0.919), Aβ42/Aβ40 ratio (AUC=0.829; 95% CI: 0.746-0.912), tTau/Aβ42 ratio (AUC=0.822; 95% CI: 0.736-0.908), pTau181/Aβ42/Aβ40 ratio (AUC=0.817; 95% CI: 0.734-0.901), and Aβ42 (AUC=0.812; 95% CI: 0.722-0.902). +4 more findings

  10. 2022 year only

    A Blood Test for Alzheimer's Disease: It's about Time or Not Ready for Prime Time?

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Standalone use, however, carries a significant risk of misinterpretation and is strongly discouraged.

  11. 2022 year only

    Blood Tests for Alzheimer's Disease: Increasing Efforts to Expand and Diversify Research Participation Is Critical for Widespread Validation and Acceptance

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: The recent academic and commercial development, and regulatory approvals, of blood-based Alzheimer's disease (AD) biomarkers are breakthrough developments of immense potential. +3 more findings

  12. 2022 year only

    Unravelling the Association Between Amyloid-PET and Cerebrospinal Fluid Biomarkers in the Alzheimer's Disease Spectrum: Who Really Deserves an A+?

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Different pipelines gave highly inter-correlated standardized uptake value ratios (SUVRs) (rho = 0.93-0.99). +4 more findings

  13. 2022 year only

    PSEN2 Mutation Spectrum and Novel Functionally Validated Mutations in Alzheimer's Disease: Data from PUMCH Dementia Cohort

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Nine PSEN2 rare variants were found, including two reported (M239T, R62C) and seven novel variants (N141S, I368F, L396I, G117X, I146T, S147N, H220Y). +4 more findings

  14. 2022 year only

    A Review of Application of Aβ42/40 Ratio in Diagnosis and Prognosis of Alzheimer's Disease

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: The amyloid cascade hypothesis attributes a vital role to amyloid-β protein (Aβ) in the pathogenesis of AD. +4 more findings

  15. 2022 year only

    Associations of Physical Activity with Alzheimer's Disease Pathologies and Cognition: The CABLE Study

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Regular physical activity was positively associated with CSF Aβ42 (p < 0.001) and Aβ42/40 (p < 0.001), while it was negatively associated with p-tau/Aβ42 (p < 0.001) and t-tau/Aβ42 (p < 0.001). +4 more findings

  16. 2022 year only

    Inflammation Disrupts Cognitive Integrity via Plasma Neurofilament Light Chain Coupling Brain Networks in Alzheimer's Disease

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Discrimination of disease-related interactions of the core subsystem and FPN was found in AD-spectrum patients, which was the neural circuit fundamental to plasma NFL disrupting cognitive integrity. +2 more findings

  17. 2022 year only
  18. 2022 year only

    Relationship Between Plasma Neurofilament Light Chain, Gut Microbiota, and Dementia: A Cross-Sectional Study

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: We analyzed 128 participants (women: 59%, mean age: 74 years). +4 more findings

  19. 2022 year only

    Plasma Neurofilament Light Chain and Clinical Diagnosis in Frontotemporal Dementia Syndromes

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Fifty participants were studied: bvFTD = 20, semantic variant FTD (svFTD) = 11, non-fluent variant FTD (nfvFTD) = 9, FTD with motor neuron disease (MND) = 4, phFTD = 2, slow progressors = 3, FTD mimic = 1, mean age 67.2 (SD 8.4) years. +4 more findings

  20. 2022 year only

    Long-Term Depression-Inducing Low Frequency Stimulation Enhances p-Tau181 and p-Tau217 in an Age-Dependent Manner in Live Rats

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: We found that LFS enhanced p-Tau181 and p-Tau217 in an age-dependent manner in the hippocampus of live rats. +4 more findings

  21. 2022 year only

    Differences Between Plasma and Cerebrospinal Fluid p-tau181 and p-tau231 in Early Alzheimer's Disease

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Plasma phosphorylated tau species have been recently proposed as peripheral markers of Alzheimer's disease (AD) pathology. +3 more findings

  22. 2022-01-01

    Diabetes duration and the risk of dementia: a cohort study based on German health claims data

    ✓ Peer-reviewed Digital health tools Age and ageing

    Key finding: We identified a non-linear association of type 2 diabetes duration and the risk of dementia.

  23. 2022-01-01

    Risk of Alzheimer's Disease Following Influenza Vaccination: A Claims-Based Cohort Study Using Propensity Score Matching

    ✓ Peer-reviewed Digital health tools Journal of Alzheimer's disease : JAD

    Key finding: This study demonstrates that influenza vaccination is associated with reduced AD risk in a nationwide sample of US adults aged 65 and older. +1 more finding

  24. 2022-01-01

    Inflammation in obesity, diabetes, and related disorders

    ✓ Peer-reviewed Risk factors Immunity

    Key finding: We discuss how chronic tissue inflammation results in IR, impaired insulin secretion, glucose intolerance, and T2D and review the effect of inflammation on diabetic complications and on the relationship between T2D and other pathologies.

  25. 2022-01-01

    Amyloid-Related Imaging Abnormalities and Other MRI Findings in a Cognitively Unimpaired Population With and Without Cerebral Amyloid

    ✓ Peer-reviewed Treatments The journal of prevention of Alzheimer's disease

    Key finding: ARIA-E is rare in cognitively unimpaired Aβ+ and Aβ- populations prior to anti-amyloid drug intervention. +3 more findings

Browse the library by subject, with the full score breakdown →