Newest studies

Dementia in a resource‐constrained sub‐Saharan African setting: A comprehensive retrospective analysis of prevalence, risk factors, and management at the only neuropsychiatric facility in Northeastern Nigeria

46/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

Key finding: Of the 1216 cases reported, Alzheimer's disease (60.5%) was the most common subtype, followed by vascular dementia (24.5%). +4 more findings

• Risk Factors
• Treatments

Full summary, score breakdown and related studies → Original source

Social Isolation as a Risk Factor for Dementia: Insights from Animal Model Studies

29/100 ✓ Peer-reviewed Risk factors Current Alzheimer Research

Key finding: Intriguingly, recent reports have shown a significant association of loneliness with a higher amyloid- β (Aβ) burden, suggesting that SI is linked to the pathophysiology of AD. +4 more findings

• Risk Factors
• Lifestyle
• Brain Biology

Full summary, score breakdown and related studies → Original source

Changes in Loneliness, Social Isolation, and Social Support: A Gender‐Disaggregated Analysis of Their Associations With Dementia and Cognitive Decline in Older Adults

47/100 ✓ Peer-reviewed Risk factors International Journal of Geriatric Psychiatry

Key finding: At baseline, participants were aged 70-95 years (mean: 75.2 ± 4.3), with 54% being women. +4 more findings

• Lifestyle
• Risk Factors

Full summary, score breakdown and related studies → Original source

Development and validation of machine learning models with blood-based digital biomarkers for Alzheimer’s disease diagnosis: a multicohort diagnostic study

52/100 ✓ Peer-reviewed Digital health tools EClinicalMedicine

Key finding: Random forest classifier and feature selection procedures were used to select digital biomarkers.

• Digital Tools
• Biomarkers
• Diagnosis

Full summary, score breakdown and related studies → Original source

Dementia prevalence and risk factors in people with and without HIV in Malawi: A medical record review

43/100 ✓ Peer-reviewed How common it is Alzheimer s & Dementia

Key finding: The overall rate of dementia was higher in PLHIV than that in POHIV (22% vs 10%; p = 1.4e). +4 more findings

• Risk Factors

Full summary, score breakdown and related studies → Original source

A deep‐learning retinal aging biomarker for cognitive decline and incident dementia

56/100 ✓ Peer-reviewed How common it is Alzheimer s & Dementia

Key finding: Of 510 memory-clinic subjects(N = 155 cognitive decline), RetiPhenoAge associated with incident cognitive decline (subdistribution hazard ratio [SHR] 1.34, 95% confidence interval [CI] 1.10-1.64, p = 0.004), and incident dementia (SHR 1.43, 95% CI 1.02-2.01, p = 0.036). +4 more findings

• Risk Factors
• Biomarkers

Full summary, score breakdown and related studies → Original source

Blood DNA methylation signature for incident dementia: Evidence from longitudinal cohorts

57/100 ✓ Peer-reviewed How common it is Alzheimer s & Dementia

Key finding: Meta-analysis identified 44 CpGs and 44 differentially methylated regions consistently associated with time to dementia in both cohorts. +4 more findings

• Risk Factors

Full summary, score breakdown and related studies → Original source

Social determinants of health and risk of dementia among older men and women: A 12‐year cohort study in Australia

46/100 ✓ Peer-reviewed How common it is Alzheimer s & Dementia

Key finding: Four clusters were identified: least disadvantaged (Class 1: 31.5% men; 30.6% women), most disadvantaged (Class 2: 20.2% men; 19.4% women), high social support with Class 1 features (Class 3: 22.2% men; 24.1% women), and high social support with Class 2 features (Class 4: 26.1% men; 25.7% women). +4 more findings

• Risk Factors
• Health Equity

Full summary, score breakdown and related studies → Original source

Community Input for Addressing Dementia Health Disparities: Richmond Brain Health Initiative

33/100 ✓ Peer-reviewed Disparities Progress in community health partnerships

Key finding: Based on the stakeholder responses from fifteen providers and twenty community members, there was strong consensus in the need for local brain health services. +4 more findings

• Health Equity
• Clinical Trials

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Process evaluation in a randomised controlled trial of DREAMS-START (dementia related manual for sleep; strategies for relatives) for sleep disturbance in people with dementia and their carers

60/100 ✓ Peer-reviewed Caregiving Age and Ageing

Key finding: Attendance was good (82.8% attended ≥4/6 sessions). +4 more findings

• Clinical Trials
• Caregiving
• Lifestyle

Full summary, score breakdown and related studies → Original source

Barriers to Accessing Care and Support Services for Older Immigrants and Immigrants with Dementia in Finland: Perspectives of Professional Social and Health Care Providers

35/100 ✓ Peer-reviewed Caregiving Journal of Cross-Cultural Gerontology

Key finding: This study addresses this gap in the research and employs semi-structured qualitative interviews with professionals offering services to this target group. +4 more findings

Full summary, score breakdown and related studies → Original source

Clinician type and care setting for treatment of Medicare beneficiaries with dementia

52/100 ✓ Peer-reviewed Caregiving Alzheimer s & Dementia

Key finding: A total of 1,934,318 PLWD received care from 783,225 unique clinicians in 2019; PLWD saw a median of eight clinicians (interquartile range 5, 14). +4 more findings

• Policy

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Optimizing Advance Care Planning in Dementia: Recommendations From a 33-Country Delphi Study

49/100 ✓ Peer-reviewed Caregiving Journal of Pain and Symptom Management

Key finding: Thirty constitutive elements of ACP were identified (e.g., 'assess understanding of ACP'). +4 more findings

• End-of-Life Care

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A look at caregivers for community‐living persons with dementia: Implications for the GUIDE model

44/100 ✓ Peer-reviewed Caregiving Alzheimer s & Dementia

Key finding: Half of GUIDE-eligible PwD received care from multiple caregivers and high strain was common even among caregivers considered "low-complexity" under GUIDE. +4 more findings

• Caregiving

Full summary, score breakdown and related studies → Original source

Burden and care time for dementia caregivers in the LIVE@Home.Path trial

59/100 ✓ Peer-reviewed Caregiving Alzheimer s & Dementia

Key finding: Caregivers during the intervention period reported lower levels of RSS of 0.7 points (standard deviation [SD]: 0.8) compared to the caregivers in the control period. +4 more findings

• Clinical Trials
• Caregiving

Full summary, score breakdown and related studies → Original source

Perfusionsmuster der [18F]PI-2620-Tau-PET bei verschiedenen neurodegenerativen Tauopathien

33/100 ✓ Peer-reviewed Brain scans and imaging Nuklearmedizin - NuclearMedicine

Key finding: Die Frühphasen- & R1-Bilder korrelierten signifikant in allen Gruppen (Gesunde: r=0,68-0,84; AD: r=0,81-0,9; PSP-RS: r=0,81-0,86; FTD: r=0,76-0,82). +4 more findings

• Brain Scans

Full summary, score breakdown and related studies → Original source

Entorhinal tau impairs short-term memory binding in preclinical Alzheimer’s disease

42/100 ✓ Peer-reviewed Brain scans and imaging Journal of the International Neuropsychological Society

Key finding: Aβ + CN individuals performed worse than Aβ-CN participants in the SCBC while the SOC only distinguished Aβ − CN from MCI participants. +3 more findings

• Early Stage

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Salivary biomarkers for the molecular diagnosis of dementia with Lewy bodies

32/100 ✓ Peer-reviewed Getting a diagnosis Journal of Alzheimer s Disease

Key finding: Alpha-synuclein (a-syn) and tau species have been detected in peripheral tissues and biological fluids of DLB patients and among different biological fluids, saliva represent an easely accessible and non-invasive source for biomarker detection. +1 more finding

• Other Dementias
• Diagnosis
• Biomarkers

Full summary, score breakdown and related studies → Original source

Cognitive assessment across normal aging and subjective cognitive decline using PGIMS and Stroop color-word test: A cross-sectional study

41/100 ✓ Peer-reviewed Getting a diagnosis Archives of Gerontology and Geriatrics Plus

Key finding: SCD individuals scored significantly lower in the Stroop color-word tests (SCWT), and delayed recall memory in PGIMS (Co-efficient: -0.11, 95%CI: -0.21 to -0.02) and -0.62; 95% CI: -1.19 to -0.04, respectively).

• Diagnosis
• Early Stage

Full summary, score breakdown and related studies → Original source

Revisiting the Montreal Cognitive Assessment in a European cohort of elderly living with type 2 diabetes

52/100 ✓ Peer-reviewed Getting a diagnosis Journal of Alzheimer s Disease

Key finding: BackgroundIndividuals with type 2 diabetes have an increased risk of developing both vascular and Alzheimer's dementia. +3 more findings

• Diagnosis
• Risk Factors

Full summary, score breakdown and related studies → Original source

Obfuscation via pitch‐shifting for balancing privacy and diagnostic utility in voice‐based cognitive assessment

48/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia

Key finding: With the top 20 acoustic features, our framework achieved classification accuracies of 62.2% (EER: 0.3335) on the FHS dataset for NC, MCI, and DE differentiation, and 63.7% (EER: 0.1796) on the DBD dataset for NC and MCI differentiation, using obfuscated speech files. +4 more findings

• Diagnosis

Full summary, score breakdown and related studies → Original source

A Self‐Powered, Shapeable, and Wearable Sensor for Effective Hazard Prevention and Biomechanical Monitoring

43/100 ✓ Peer-reviewed Prevention and risk SmartSys

Key finding: Flexible and wearable electronics are attracting surging attention due to their potential applications in human health monitoring and precision therapies. +4 more findings

• Digital Tools
• Prevention

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Gender Diversity and Environmental, Social, and Governance: Unlocking Solutions to Corporate Risk

46/100 ✓ Peer-reviewed Prevention and risk Business Strategy & Development

Key finding: The findings indicate that stronger ESG practices significantly reduce corporate risk, enhance financial stability, and mitigate regulatory and market volatility exposure. +2 more findings

• Policy

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Fast AI Based Amyloid PET Reporting – can Nuclear Medicine Handle the Expected Workload in Alzheimers Diagnostics?

30/100 ✓ Peer-reviewed Biomarkers Nuklearmedizin - NuclearMedicine

Key finding: The deep-learning network was capable of learning the task of delineating pathologic and normal findings within minutes on a standard PC and performing the classification task with 100% accuracy in less than 1 millisecond per case. +4 more findings

• Digital Tools
• Brain Scans

Full summary, score breakdown and related studies → Original source

Neuroprotective role of Origanum majorana essential oil loaded in mixed surfactants based nano emulsion against lipopolysaccharide-induced Alzheimer in mice

35/100 ✓ Peer-reviewed Biomarkers Journal of Pharmaceutical Investigation

Key finding: The current study provides opportunities for safer approaches that using compounds derived from plants and links it to nanotechnology, could be used in the pharmaceutical industry to treat Alzheimer’s disease. +1 more finding

• Brain Biology

Full summary, score breakdown and related studies → Original source