Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 4,476–4,500 of 27,380 studies, newest first · page 180 of 1096.
April 2025 25
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2025-04-29
ApoE4 requires lipidation enhancement to resolve cellular lipid and protein abnormalities following NPC1 inhibition
43/100 ✓ Peer-reviewed Genetics Scientific reports
Key finding: Total APP, APP C-terminal fragments (CTF) and BACE1 levels increased 3-fold. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-29
Incidence and Risk Factors of Delirium in COPD Patient in Intensive Care Unit
36/100 ✓ Peer-reviewed Clinical safety Archives of Neuroscience
Key finding: Of the 74 patients examined, 19 (25.7%) experienced delirium, while 55 (74.3%) showed no symptoms of delirium. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-29
Association of Mediterranean Diet With Cognitive Decline Among Diverse Hispanic or Latino Adults From the Hispanic Community Health Study/Study of Latinos
50/100 ✓ Peer-reviewed Prevention trials Carolina Digital Repository (University of North Carolina at Chapel Hill)
Key finding: A total of 6321 participants (mean [SE] age, 56.1 [0.18] years at visit 1; n = 4077 women [57.8%]) were included. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-29
Could a Mediterranean Diet Modulate Alzheimer’s Disease Progression? The Role of Gut Microbiota and Metabolite Signatures in Neurodegeneration
56/100 ✓ Peer-reviewed Prevention trials Foods
Key finding: Recent studies have shown that neurodegeneration through complex interactions within the gut-brain axis largely depends on the gut microbiota and its metabolites. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-04-29
Functional Specificity of Astrocyte Subtypes in Alzheimer’s Disease: Decoding Disease Mechanisms Through Network-based Analysis of Integrated Single-Nuclei Multi-Omic Data
37/100 ✓ Peer-reviewed Inflammation and the immune system Molecular Neurobiology
Key finding: Recent studies have revealed incontrovertible roles of astrocytes in the pathology of AD. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-29
A comparison of cognitive and health assessment tools used in a dementia prevention and risk management program for urban-dwelling older aboriginal Australians (DAMPAA)
36/100 ✓ Peer-reviewed Cognitive tests and assessment SSM - Mental Health
Key finding: There were weak or no correlations between the KICA-Cog and other cognitive assessment tools. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-29
Multipotent Mesenchymal Stem Cell Therapy for Vascular Dementia
38/100 ✓ Peer-reviewed Lewy body dementia Cells
Key finding: MMSCs treatment significantly improved both working memory and long-term memory. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-29
Multifaceted role of nitric oxide in vascular dementia
38/100 ✓ Peer-reviewed Lewy body dementia Medical Gas Research
Key finding: Currently, there are no definitive treatments for the cognitive dysfunction associated with vascular dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-29
A Complementary Dataset of Scalp EEG Recordings Featuring Participants with Alzheimer’s Disease, Frontotemporal Dementia, and Healthy Controls, Obtained from Photostimulation EEG
44/100 ✓ Peer-reviewed Digital health tools Data
Key finding: Our previously published open-access dataset of resting-state (eyes-closed) EEG recordings from patients with Alzheimer’s disease (AD), frontotemporal dementia (FTD), and cognitively normal (CN) controls has attracted significant attention. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-04-29
Metabolic dysfunction-associated steatotic liver disease, metabolic alcohol-related liver disease, and incident dementia: a nationwide cohort study
58/100 ✓ Peer-reviewed How common it is BMC Gastroenterology
Key finding: Over 7,430,253 person-years of follow-up, 11,345 dementia cases occurred (10,863 AD and 2,159 VaD). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-29
Feasibility and Acceptability of Implementing a Digital Cognitive Assessment for Alzheimer Disease and Related Dementias in Primary Care
52/100 ✓ Peer-reviewed Getting a diagnosis The Annals of Family Medicine
Key finding: There were 16,708 eligible encounters during the 12-month study period (June 2022-May 2023). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-29
Agile Implementation of a Digital Cognitive Assessment for Dementia in Primary Care
45/100 ✓ Peer-reviewed Getting a diagnosis The Annals of Family Medicine
Key finding: The intervention engaged 69 (63.8%) of 108 clinicians across the 7 clinics. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-28
LATE-NC Stage 3: a diagnostic rubric to differentiate severe LATE-NC from FTLD-TDP
55/100 ✓ Peer-reviewed Brain tissue and pathology Acta neuropathologica
Key finding: There was no difference in the Alzheimer's disease pathological load in LATE-NC Stages 2 versus 3. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-28
The Association of Ambient Air Pollution With Dynamic Transitions of Cataract and Dementia: A UK Biobank Study
47/100 ✓ Peer-reviewed Long-term cohort studies International Journal of Geriatric Psychiatry
Key finding: Our study suggested that the long‐term exposure to air pollution was associated an increased risk of the transitions from health to incident cataract, dementia or the progression of both conditions. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-04-28
Assessment of localized brain regions correlated with MMSE using VBM analysis of structural MRI in a Japanese sample
44/100 ✓ Peer-reviewed Cognitive tests and assessment Neuroimage Reports
Key finding: The global aging population has led to a significant rise in dementia and cognitive decline, with Alzheimer's disease as the primary cause. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-28
Evaluation of Illumina and Oxford Nanopore Sequencing for the Study of DNA Methylation in Alzheimer’s Disease and Frontotemporal Dementia
41/100 ✓ Peer-reviewed Lewy body dementia International Journal of Molecular Sciences
Key finding: Alterations in DNA methylation patterns are associated with various brain disorders, including dementias such as Alzheimer's disease (AD) and frontotemporal dementia (FTD).
Full summary, score breakdown and related studies → Original source
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2025-04-28
Monoallelic TYROBP deletion is a novel risk factor for Alzheimer’s disease
44/100 ✓ Peer-reviewed Risk factors Molecular Neurodegeneration
Key finding: We show that monoallelic TYROBP deletion associates with an increased risk and earlier onset age of AD and dementia when compared to noncarriers. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-28
Artificial intelligence in drug development for delirium and Alzheimer’s disease
44/100 ✓ Peer-reviewed Digital health tools Acta Pharmaceutica Sinica B
Key finding: Delirium is a common cause and complication of hospitalization in the elderly and is associated with higher risk of future dementia and progression of existing dementia, of which 70% is Alzheimer's disease (AD). +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-28
Clinical Evolution of Neuropsychiatric Symptoms in Alzheimer's Disease and Dementia With Lewy Bodies in a Post‐Mortem Cohort
59/100 ✓ Peer-reviewed How common it is International Journal of Geriatric Psychiatry
Key finding: Early onset hallucinations were significantly more common in pLBD than pAD (OR 0.069 [95% CI 0.012-0.397], p = 0.003) or mixed AD+LBD (OR 0.09 [95% CI 0.010-0.771], p = 0.028) and there was a greater increase in the odds of hallucinations over time in pAD and AD+LBD than pLBD such that there was was no difference in the prevalence of late-onset hallucinations between pLBD, pAD or AD+LBD. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-28
Antihypertensive drug classes and risk of incident dementia: a multinational population-based cohort study
64/100 ✓ Peer-reviewed How common it is Age and Ageing
Key finding: One million nine hundred twenty-five thousand, five hundred sixty-three individuals were included across the four databases with a median follow-up ranging from 5.6 to 8.4 years. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-28
Longitudinal Remote Sleep and Cognitive Research in Older Adults With Mild Cognitive Impairment and Dementia: Prospective Feasibility Cohort Study
57/100 ✓ Peer-reviewed Getting a diagnosis JMIR Aging
Key finding: In total, 41 participants consented (n=10, 24% participants with Alzheimer disease; n=11, 27% participants with Lewy body disease; and n=20, 49% controls). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-28
Interventions That Support Lifestyle Behavior Change for Secondary Prevention of Stroke: A Scoping Review
53/100 ✓ Peer-reviewed Prevention and risk Stroke
Key finding: Interventions associated with improvements were more commonly delivered by a multidisciplinary team and informed by behavior change techniques.
Full summary, score breakdown and related studies → Original source
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2025-04-28
Comparative Brain and Serum Exosome Expression of Biomarkers in an Experimental Model of Alzheimer-Type Neurodegeneration: Potential Relevance to Liquid Biopsy Diagnostics
34/100 ✓ Peer-reviewed Biomarkers International Journal of Molecular Sciences
Key finding: STZ significantly impacted FLEV and SEV nanoparticle abundance and size distributions and concordantly increased AD (Tau, pTau, and Aβ) and oxidative stress (ubiquitin, 4-HNE) biomarkers, as well as immunoreactivity to immature oligodendrocyte (PLP), non-myelinating glial (PDGFRA, GALC) proteins, MAG, nestin, and GFAP in FLTX and FLEV. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-04-26
Caregiver Support Program May Decrease Work-Family Conflict: An Intervention Study
43/100 ✓ Peer-reviewed Caregiving Inquiry : a journal of medical care organization, provision and financing
Key finding: Compared to the rich studies on the caregiving impact on the mental and physical health of caregivers, the intricacies of the work-family relationship have been limited, particularly concerning the dementia caregivers. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-04-26
Diagnosis, pathomechanisms and therapy of cerebral amyloid angiopathy-related inflammation (CAA-ri)
43/100 ✓ Peer-reviewed Treatments Neurological research and practice
Key finding: CAA-ri gains increasing interest as a spontaneous human model of iatrogenic edematous amyloid-related imaging abnormalities (ARIA-E) in the context of amyloid-modifying therapies. +4 more findings
Full summary, score breakdown and related studies → Original source
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