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Faith-Based Lifestyle Intervention for Diabetes Prevention Among Adults in Bangladesh
Bishwajit Bhowmik, Tasnima Siddiquee, Sanjida Binte Munir, Hafiza Nasrin, Tanjimul Islam, Tamanna Afroz, Liya Quamrun Nesa, Shamim Khan et al.. JAMA Network Open, 2025-10-20
Topic: Risk, prevention and care in population studies
Of the 799 participants (mean [SD] age, 46.2 [11.6] years; 424 women [53.1%]) randomized, 641 completed the 12-month follow-up and were included in the intention-to-treat analysis: 341 (n = 4 mosques) in the intervention group and 300 (n = 4 mosques) in the control group. The intervention group had a significantly lower 12-month cumulative T2D incidence (9.8% [95% CI, 7.1%-13.5%]) vs the control group (17.1% [95% CI, 13.4%-21.6%]), with an absolute risk reduction of 7.3 percentage points (95% CI, 5.2-10.6 percentage points), a relative risk reduction of 42.5% (95% CI, 15.0%-70.0%), and a number needed to treat of 14 (95% CI, 9-39). In Cox proportional hazards regression adjusted for clustering, the hazard ratio was 0.75 (95% CI, 0.60-0.95; P = .02), corresponding to a 25.0% reduction in diabetes risk. Secondary outcomes including weight, BMI, fasting glucose, 2-hour blood glucose, hemoglobin A1c, lipid profiles, diabetes-related knowledge, physical activity, and quality of life also improved significantly more in the intervention group compared with the control group. Conclusions and Relevance: In this cluster RCT involving adults with prediabetes, a culturally adapted, mosque-based lifestyle intervention significantly reduced T2D incidence over 12 months in rural Bangladesh. These results demonstrate the potential for scalable and cost-effective diabetes prevention programs in low-resource, Muslim-majority communities. Trial Registration: ISRCTN Registry Identifier: ISRCTN91564707.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Bhowmik, B., Siddiquee, T., Munir, S. B., Nasrin, H., Islam, T., Afroz, T., et al. (2025). Faith-Based Lifestyle Intervention for Diabetes Prevention Among Adults in Bangladesh. JAMA Network Open. https://doi.org/10.1001/jamanetworkopen.2025.38101
Vancouver
Bhowmik B, Siddiquee T, Munir SB, Nasrin H, Islam T, Afroz T, et al. Faith-Based Lifestyle Intervention for Diabetes Prevention Among Adults in Bangladesh. JAMA Network Open. 2025. doi:10.1001/jamanetworkopen.2025.38101. PMID: 41114978.
BibTeX
@article{bhowmik2025-41114978,
author = {Bhowmik, Bishwajit and Siddiquee, Tasnima and Munir, Sanjida Binte and Nasrin, Hafiza and Islam, Tanjimul and Afroz, Tamanna and Nesa, Liya Quamrun and Khan, Shamim and others},
title = {{Faith-Based Lifestyle Intervention for Diabetes Prevention Among Adults in Bangladesh}},
journal = {JAMA Network Open},
year = {2025},
doi = {10.1001/jamanetworkopen.2025.38101},
pmid = {41114978},
url = {https://doi.org/10.1001/jamanetworkopen.2025.38101}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
Key findings
- Of the 799 participants (mean [SD] age, 46.2 [11.6] years; 424 women [53.1%]) randomized, 641 completed the 12-month follow-up and were included in the intention-to-treat analysis: 341 (n = 4 mosques) in the intervention group and 300 (n = 4 mosques) in the control group.
- The intervention group had a significantly lower 12-month cumulative T2D incidence (9.8% [95% CI, 7.1%-13.5%]) vs the control group (17.1% [95% CI, 13.4%-21.6%]), with an absolute risk reduction of 7.3 percentage points (95% CI, 5.2-10.6 percentage points), a relative risk reduction of 42.5% (95% CI, 15.0%-70.0%), and a number needed to treat of 14 (95% CI, 9-39).
- In Cox proportional hazards regression adjusted for clustering, the hazard ratio was 0.75 (95% CI, 0.60-0.95; P = .02), corresponding to a 25.0% reduction in diabetes risk.
- Secondary outcomes including weight, BMI, fasting glucose, 2-hour blood glucose, hemoglobin A1c, lipid profiles, diabetes-related knowledge, physical activity, and quality of life also improved significantly more in the intervention group compared with the control group.
- Conclusions and Relevance: In this cluster RCT involving adults with prediabetes, a culturally adapted, mosque-based lifestyle intervention significantly reduced T2D incidence over 12 months in rural Bangladesh.
Why it matters
This study was about preventing type 2 diabetes, not Alzheimer's disease, so it provides no direct information about treating, curing or preventing Alzheimer's. It found that a mosque-based lifestyle program in rural Bangladesh reduced new cases of type 2 diabetes over 12 months.
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Study details
- Participants799
- Effect size53.1%; 9.8%; 7.1%
- Evidence strengthHigh
How this study scored 52/100
Published in a leading specialty journal. Scored zero for study design and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (JAMA Network Open) |
| Journal's citation record | 2 / 4 | JAMA Network Open: journal h-index 235 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 2 / 4 | 799 participants |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 2 / 7 | Cited 8 times (OpenAlex, 2026-10-10) |
| Citations per year | 1 / 5 | 2.7 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 3 / 6 | Cited 4.8× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 8 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Abul Kalam Azad Khan: h-index 23 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | University of Central Arkansas: institution h-index 137 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 4 institution(s) in 3 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 41114978) |
| Free to read | 2 / 2 | Free to read |
| Total | 52 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1001/jamanetworkopen.2025.38101
- PubMed: 41114978
- Original source →
- Free full text: JAMA Network Open →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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