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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 26,801–26,825 of 27,380 studies, newest first · page 1073 of 1096.

February 1993 3

  1. 1993-02-01

    Pick's disease versus Alzheimer's disease: a comparison of clinical characteristics

    ✓ Peer-reviewed Digital health tools Neurology

    Key finding: These findings suggest that Pick patients are potentially distinguishable from AD patients on the basis of clinical manifestations.

    Full summary, score breakdown and related studies → Original source

  2. 1993-02-01

    Making the diagnosis of Alzheimer's disease. A primer for practicing pathologists

    ✓ Peer-reviewed Getting a diagnosis Archives of pathology & laboratory medicine

    Key finding: There is demand on community pathologists to perform autopsies to confirm the clinical diagnosis of Alzheimer's disease, the most common cause of dementia in our increasingly aging society. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1993-02-01

    Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: Compared with other current criteria, these guidelines emphasize (1) the heterogeneity of vascular dementia syndromes and pathologic subtypes including ischemic and hemorrhagic strokes, cerebral hypoxic-ischemic events, and senile leukoencephalopathic lesions; (2) the variability in clinical course, which may be static, remitting, or progressive; (3) specific clinical findings early in the course (eg, gait disorder, incontinence, or mood and personality changes) that support a vascular rather than a degenerative cause; (4) the need to establish a temporal relationship between stroke and dementia onset for a secure diagnosis; (5) the importance of brain imaging to support clinical findings; (6) the value of neuropsychological testing to document impairments in multiple cognitive domains; and (7) a protocol for neuropathologic evaluations and correlative studies of clinical, radiologic, and neuropsychological features.

    Full summary, score breakdown and related studies → Original source

January 1993 16

  1. 1993-01-01

    The economic burden of Alzheimer's disease care

    ✓ Peer-reviewed Caregiving Health affairs (Project Hope)

    Key finding: For community-resident patients, three-fourths of the total cost represents an imputed value for unpaid informal care compared with 12 percent for institutionalized patients. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1993-01-01

    Blood-brain barrier penetration and in vivo activity of an NGF conjugate

    ✓ Peer-reviewed Brain scans and imaging Science (New York, N.Y.)

    Key finding: However, NGF does not significantly penetrate the blood-brain barrier, which makes its clinical utility dependent on invasive neurosurgical procedures.

    Full summary, score breakdown and related studies → Original source

  3. 1993-01-01

    Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide

    ✓ Peer-reviewed Tau biomarkers Nature

    Key finding: The amyloid precursor protein (APP)4 from which A beta is derived is subject to several genetic mutations which segregate with rare familial forms of the disease, resulting in early onset of dementia and plaque formation, suggesting that APP metabolism plays a causal role in the disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 1993-01-01

    The origin and nature of ramified and amoeboid microglia: a historical review and current concepts

    ✓ Peer-reviewed Tau biomarkers Glia

    Key finding: It is known that ramified microglial cells do not divide under normal circumstances, and since our studies in the corpus callosum have shown that these cells do not appear until the fifth postnatal day, it is reasoned that they must be derived from some preexisting mitotically active cells. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1993-01-01

    Autosomal dominant leukoencephalopathy and subcortical ischemic stroke. A clinicopathological study

    ✓ Peer-reviewed Vascular contributions Stroke

    Key finding: The underlying lesion of this hereditary disorder is located in the small arteries and is of unknown etiology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1993-01-01

    What is appropriate health care for end-stage dementia?

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: Professional and family members of demented individuals, especially if they have experience in terminal care decisions, strongly favor palliative care for end-stage dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1993-01-01

    Quantitative synaptic alterations in the human neocortex during normal aging

    ✓ Peer-reviewed Disease mechanisms Neurology

    Key finding: We quantified the synaptic population density in the frontal cortex of 25 individuals without dementia 16 to 98 years old, using sections double-immunolabeled for beta/A4 amyloid and for synaptophysin, and found a significant inverse correlation between the presynaptic terminal (PT) counts and age (r = -0.7, p < 0.001). +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1993 no date recorded — placed by publication year

    Education and the prevalence of dementia and Alzheimer's disease

    ✓ Peer-reviewed Risk factors Neurology

    Full summary, score breakdown and related studies → Original source

  9. 1993-01-01

    [Screening for mutations of the precursor of beta-amyloid protein in early forms of Alzheimer disease. French Study Group of Alzheimer Disease]

    ✓ Peer-reviewed Risk genes beyond APOE Revue neurologique

    Key finding: Genetic linkage studies suggest that Alzheimer's disease (AD) is genetically heterogeneous and that in several early onset families the disease locus is close to the amyloid precursor protein (APP) gene on chromosome 21. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 1993-01-01

    Identification of the Alzheimer beta/A4 amyloid precursor protein in clathrin-coated vesicles purified from PC12 cells

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: To further investigate the possibility of APP processing in the endosomal/lysosomal system, we have examined whether APP is present in clathrin-coated vesicles (CCVs), which mediate the transport of many proteins to the endosomal compartment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 1993-01-01

    Lack of detectable radiation hypersensitivity in lymphoblastoid cells from multiple pedigrees of familial Alzheimer disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Alzheimer disease and associated disorders

    Key finding: Recent reports suggest that cultivated nonneuronal cells from individuals with Alzheimer disease (AD) and other specific hereditary neurodegenerative disorders show hypersensitivity to DNA-damaging agents such as x-rays and radiomimetic chemicals. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 1993-01-01

    [Transgenic mice overexpressing copper-zinc superoxide dismutase: a model for the study of radical mechanisms and aging]

    ✓ Peer-reviewed Down syndrome and Alzheimer's Comptes rendus des seances de la Societe de biologie et de ses filiales

    Key finding: It has been suggested that this increment, by accelerating hydrogen peroxide formation, might promote oxidative damage within DS cells and might be involved in the various neurobiological abnormalities found in DS such as premature aging and Alzheimer-type neurological lesions. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 1993-01-01

    Human carbonyl reductase (CBR) localized to band 21q22.1 by high-resolution fluorescence in situ hybridization displays gene dosage effects in trisomy 21 cells

    ✓ Peer-reviewed Down syndrome and Alzheimer's Genomics

    Key finding: Both aldo-keto reductase activity and quinone reductase activity have been shown to be associated with carbonyl reductase.

    Full summary, score breakdown and related studies → Original source

  14. 1993-01-01

    Segmental trisomy as a mouse model for Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Progress in clinical and biological research

    Key finding: Mice trisomic for Chromosome (Chr) 16 have been used extensively as an animal model for human Down Syndrome (Trisomy 21). +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 1993-01-01

    A population-based study of dementia in 85-year-olds

    ✓ Peer-reviewed How common it is The New England journal of medicine

    Key finding: Dementia was present in nearly a third of unselected 85-year-olds in Sweden. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 1993-01-01

    The role of cortical connectivity in Alzheimer's disease pathogenesis: a review and model system

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of aging

    Key finding: Much of the evidence for this model has been obtained from studies involving the limbic system where investigators have demonstrated a precise correspondence between established patterns of connectivity and the degenerative changes associated with AD.

    Full summary, score breakdown and related studies → Original source

December 1992 6

  1. 1992-12-01

    Bedside assessment of executive cognitive impairment: the executive interview

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: These preliminary findings suggest that the EXIT is a valid and reliable instrument for the assessment of executive impairment at the bedside. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1992-12-01

    Brain morphology and schizophrenia. A magnetic resonance imaging study of limbic, prefrontal cortex, and caudate structures

    ✓ Peer-reviewed Hippocampus size on brain scans Archives of general psychiatry

    Key finding: Schizophrenic patients, compared with healthy controls, had significantly smaller right and left amygdala/hippocampal complex volumes, smaller right and left prefrontal volumes, and larger left caudate volumes. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1992-12-01

    An empirical study of delirium subtypes

    ✓ Peer-reviewed Clinical safety The British journal of psychiatry : the journal of mental science

    Key finding: There were no statistically significant differences between the groups with respect to age, sex, place of residence, or presence of dementia.

    Full summary, score breakdown and related studies → Original source

  4. 1992-12-01

    Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

    ✓ Peer-reviewed Risk genes beyond APOE Nature

    Full summary, score breakdown and related studies → Original source

  5. 1992-12-01

    MHC class II-positive microglia in human brain: association with Alzheimer lesions

    ✓ Peer-reviewed Inflammation and the immune system Journal of neuroscience research

    Key finding: Previous studies of normal human brain samples reported MHC class II expression primarily by perivascular MPS cells and white matter microglial cells. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1992-12-01

    Assessment of behavioral problems in dementia: the revised memory and behavior problems checklist

    ✓ Peer-reviewed Caregiving Psychology and aging

    Key finding: Overall scale reliability was good, with alphas of .84 for patient behavior and .90 for caregiver reaction.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →