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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 26,301–26,325 of 27,380 studies, newest first · page 1053 of 1096.

October 1996 13

  1. 1996-10-01

    Diagnostic guidelines in central nervous system Whipple's disease

    ✓ Peer-reviewed Disease mechanisms Annals of Neurology

    Key finding: Review of the 84 cases of CNS Whipple's disease (81 in the literature, 3 new) revealed that 80% of the patients had systemic signs. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1996-10-01

    NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

    ✓ Peer-reviewed Disease mechanisms Biochemistry

    Key finding: Circular dichroism (CD) and Fourier-transform infrared spectroscopy (FTIR) indicate the absence of significant amounts of secondary structure in NACP, while CD and ultraviolet spectroscopy suggest the lack of a hydrophobic core. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 1996-10-01

    Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

    ✓ Peer-reviewed Brain tissue and pathology Nature

    Key finding: Hyperphosphorylation of tau results in its inability to bind to microtubules and is believed to precede PHF assembly. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 1996-10-01

    Hippocampal synaptic transmission enhanced by low concentrations of nicotine

    ✓ Peer-reviewed Prevention and risk Nature

    Key finding: Measurements of intracellular Ca2+ in single mossy-fibre presynaptic terminals indicate that nAChRs containing the alpha7 subunit can mediate a Ca2+ influx that is sufficient to induce vesicular neurotransmitter release. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 1996-10-01

    Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

    ✓ Peer-reviewed Risk genes beyond APOE Nature

    Key finding: Analysis of these mice showed that overexpression of mutant, but not wild-type, PS1 selectively increases brain A beta42(43). +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 1996-10-01

    Treatment of the dying in the acute care hospital. Advanced dementia and metastatic cancer

    ✓ Peer-reviewed End-of-life care Archives of internal medicine

    Key finding: Incurably ill patients often receive nonpalliative interventions at the end of life. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1996-10-01

    Familial amyotrophic lateral sclerosis with a mutation in exon 4 of the Cu/Zn superoxide dismutase gene: pathological and immunocytochemical changes

    ✓ Peer-reviewed Clinical safety Acta neuropathologica

    Key finding: These findings suggest a primary failure of axonal maintainance affecting several neuronal groups with long projecting axons. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 1996-10-01

    Specific domains of beta-amyloid from Alzheimer plaque elicit neuron killing in human microglia

    ✓ Peer-reviewed Inflammation and the immune system The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: A recent study has shown that microglia placed in contact with isolated plaque fragments release neurotoxins. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1996-10-01

    Longitudinal analysis of the association between depressive symptomatology and cognitive deterioration

    ✓ Peer-reviewed Cognitive tests and assessment American journal of epidemiology

    Key finding: The purpose of this analysis was to determine whether high depressive symptomatology is predictive of cognitive deterioration among the elderly 3 years later. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1996-10-01

    The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology

    ✓ Peer-reviewed Risk genes beyond APOE Nature medicine

    Key finding: A beta 42 aggregates readily and appears to provide a nidus for the subsequent aggregation of A beta 40 (ref. 4), resulting in the formation of innumerable neuritic plaques. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 1996-10-01

    Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

    ✓ Peer-reviewed Lewy body dementia Nature

    Key finding: CADASIL (for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) causes a type of stroke and dementia whose key features include recurrent subcortical ischaemic events and vascular dementia and which is associated with diffuse white-matter abnormalities on neuroimaging.

    Full summary, score breakdown and related studies → Original source

  12. 1996-10-01

    Estrogen replacement therapy and risk of Alzheimer disease

    ✓ Peer-reviewed How common it is Archives of internal medicine

    Key finding: This study suggests that estrogen replacement therapy may be useful for preventing or delaying the onset of Alzheimer disease in postmenopausal women. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 1996-10-01

    The relationship between alcohol consumption, cognitive performance, and daily functioning in an urban sample of older black Americans

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: Previous research on effects of alcohol on health indices have suggested a J-shaped relationship between amounts of alcohol consumption and measurements of heart disease, stroke, and mortality rates. +2 more findings

    Full summary, score breakdown and related studies → Original source

September 1996 12

  1. 1996-09-15

    Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms PubMed Central

    Key finding: Overexpression of mutated human amyloid precursor protein (hAPP717V-->F) under control of platelet-derived growth factor promoter (PDAPP minigene) in transgenic (tg) mice results in neurodegenerative changes similar to Alzheimer's disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1996-09-01

    The Evolution of Psychiatric Symptoms in Alzheimer's Disease: A Natural History Study

    ✓ Peer-reviewed Clinical safety Journal of the American Geriatrics Society

    Key finding: Irritability, agitation, and aggression were documented in 81 patients (81%) an average of 10 months after diagnosis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1996-09-01

    Microglial Cells Internalize Aggregates of the Alzheimer's Disease Amyloid β-Protein Via a Scavenger Receptor

    ✓ Peer-reviewed Inflammation and the immune system Neuron

    Key finding: Microglia are immune system cells associated with Alzheimer's disease plaques containing beta-amyloid (A beta). +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1996-09-01

    Neurodegenerative diseases: occupational occurrence and potential risk factors, 1982 through 1991

    ✓ Peer-reviewed Risk factors American journal of public health

    Key finding: Neurodegenerative disease occurs more frequently in some occupations than in others, and this distribution, which may indicate occupational risk factors, should be further investigated.

    Full summary, score breakdown and related studies → Original source

  5. 1996-09-01

    Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

    ✓ Peer-reviewed Genetics Nature genetics

    Key finding: The apolipoprotein E (APOE) E4 allele is associated with Alzheimer's disease, cardiovascular disease, and decreased longevity.

    Full summary, score breakdown and related studies → Original source

  6. 1996-09-01

    Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay

    ✓ Peer-reviewed Tau biomarkers The Journal of biological chemistry

    Key finding: Although betaA4 1-40 is the major form produced by cell metabolism and found in CSF, recent observations suggest that the long-tailed betaA4 1-42 plays a more crucial role in AD pathogenesis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1996-09-01

    Psychiatric morbidity in terminally ill cancer patients. A prospective study

    ✓ Peer-reviewed Cognitive tests and assessment Cancer

    Key finding: In the study by Derogatis et al., which included patients with all stages of cancer, 47% of the patients met the DSM-III criteria for a psychiatric disorder, with adjustment disorders being the most common. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1996-09-01

    The Mini-Mental State Examination in general medical practice: clinical utility and acceptance

    ✓ Peer-reviewed Cognitive tests and assessment Mayo Clinic proceedings

    Key finding: The efficacy of the MMSE for screening was measured in a subsample of age- and sex-matched patients with dementia (N = 185) and control subjects (N = 227). +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1996-09-01

    In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis

    ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of aging

    Key finding: Activated astrocytes, overexpressing S100 beta, are a prominent feature of these neuritic plaques, and the neurite growth-promoting properties of S100 beta have been implicated in the formation of dystrophic neurites overexpressing beta-APP in neuritic plaques. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1996-09-01

    Decreased cyclin dependent kinase in brain of patients with Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Neuroscience letters

    Key finding: The major finding of our study was the remarkable and significant decrease of CDK protein and activity in DS brains in comparison to AD and controls.

    Full summary, score breakdown and related studies → Original source

  11. 1996-09-01

    Alzheimer-type pathology in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS)

    ✓ Peer-reviewed Down syndrome and Alzheimer's Acta neuropathologica

    Key finding: The results suggest a possible correlation between this mitochondrial DNA abnormality and Alzheimer-type pathology.

    Full summary, score breakdown and related studies → Original source

  12. 1996-09-01

    N400 evidence of abnormal responses to speech in Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Electroencephalography and clinical neurophysiology

    Key finding: The N400 priming effect was not smaller during the phonemic than semantic task in any group, suggesting that the semantic qualities of speech are processed even when subjects are attending to phonemic qualities.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →