Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 26,451–26,475 of 27,380 studies, newest first · page 1059 of 1096.
December 1995 11
-
1995-12-01
Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients
36/100 ✓ Peer-reviewed Tau biomarkers Neuroscience letters
Key finding: IL-1 beta and IL-6 contents were significantly elevated in the CSF of de novo PD and AD patients in comparison to the control group. +2 more findings
Full summary, score breakdown and related studies → Original source
-
1995-12-01
Epidemiology of Presenile Alzheimer's Disease in Scotland (1974–88)
33/100 ✓ Peer-reviewed Risk factors The British Journal of Psychiatry
Key finding: We found that an ecological measure of socio-economic deprivation was related to VaD but not to AD PSD. +4 more findings
Full summary, score breakdown and related studies → Original source
-
1995-12-01
Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity
54/100 ✓ Peer-reviewed Cognitive tests and assessment Lancet (London, England)
Key finding: Several groups have developed transgenic models that overexpress the amyloid precursor protein or beta-amyloid and then develop AD-like neuropathology. +3 more findings
Full summary, score breakdown and related studies → Original source
-
1995-12-01
Autobiographical memory and executive function in early dementia of Alzheimer type
47/100 ✓ Peer-reviewed Cognitive tests and assessment Neuropsychologia
Key finding: Autobiographical memory, as assessed by autobiographical fluency and the Autobiographical Memory Interview (AMI), was impaired in DAT patients, even those with minimal disease. +3 more findings
Full summary, score breakdown and related studies → Original source
-
1995-12-01
[Parapsychotic disorders in mentally handicapped (particularly in Down's syndrome)]
27/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Annales medico-psychologiques
Key finding: It starts with loosing vital aim and long lasting soliloquy. +4 more findings
Full summary, score breakdown and related studies → Original source
-
1995-12-01
Chronic elevation of S100 beta protein does not alter APP mRNA expression or promote beta-amyloid deposition in the brains of aging transgenic mice
33/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Brain research
Key finding: These results leave open the possibility of focal changes in APP transcription and do not address possible effects of S100 beta on the complex processing known to occur with APP protein. +1 more finding
Full summary, score breakdown and related studies → Original source
-
1995-12-01
Neuropsychological test performance in African-American and white patients with Alzheimer's disease
46/100 ✓ Peer-reviewed Disparities Neurology
Key finding: Little information exists on the performance of black versus white patients with Alzheimer's disease on neuropsychological tests for dementia. +1 more finding
Full summary, score breakdown and related studies → Original source
-
1995-12-01
Psychiatric and physical morbidity effects of dementia caregiving: prevalence, correlates, and causes
50/100 ✓ Peer-reviewed Caregiving The Gerontologist
Key finding: Physical morbidity was associated with patient problem behaviors and cognitive impairment, and with caregiver depression, anxiety, and perceived social support.
Full summary, score breakdown and related studies → Original source
-
1995-12-01
Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease?
46/100 ✓ Peer-reviewed Getting a diagnosis Molecular and chemical neuropathology
Key finding: A marked increase in CSF-PHFtau was found in AD (2230 +/- 930 pg/mL), as compared with controls (640 +/- 230 pg/mL; p < 0.0001), vascular dementia, VAD (1610 +/- 840 pg/mL; p < 0.05), frontal lobe dementia, FLD (1530 +/- 1000 pg/mL; p < 0.05), Parkinson disease, PD (720 +/- 590 pg/mL; p < 0.0001), and patients with major depression (230 +/- 130 pg/mL; p < 0.0001). +1 more finding
Full summary, score breakdown and related studies → Original source
-
1995-12-01
Episodic memory changes are associated with the APOE-epsilon 4 allele in nondemented older adults
47/100 ✓ Peer-reviewed Genetics Neurology
Key finding: APOE- epsilon 4 and non-epsilon 4 groups did not significantly differ in demographic, mental status, and functional characteristics. +2 more findings
Full summary, score breakdown and related studies → Original source
-
1995-12-01
Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease
51/100 ✓ Peer-reviewed Genetics Proceedings of the National Academy of Sciences of the United States of America
Key finding: ApoE4 is associated with sporadic and late-onset familial Alzheimer disease (AD). +2 more findings
Full summary, score breakdown and related studies → Original source
November 1995 10
-
1995-11-01
Pain evaluation and management in the nursing home
40/100 ✓ Peer-reviewed Health systems and care delivery Annals of internal medicine
Key finding: Elderly nursing home residents are more sensitive to the side effects associated with many analgesic drugs, but this does not justify the failure to treat pain, especially in those who are terminally ill or near the end of life.
Full summary, score breakdown and related studies → Original source
-
1995-11-01
Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation
36/100 ✓ Peer-reviewed Disease mechanisms Journal of neurochemistry
Key finding: These endpoints indicate that AD brain protein may be more oxidized than that of control subjects. +2 more findings
Full summary, score breakdown and related studies → Original source
-
1995-11-01
Life-sustaining treatment preferences of hemodialysis patients: implications for advance directives
72/100 ✓ Peer-reviewed End-of-life care Journal of the American Society of Nephrology : JASN
Key finding: Mean ADAQ scores were: Dialysis Living Will, 71%; Centre for Bioethics Living Will, 70%; and Medical Directive, 60% (F = 8.27, P < 0.001 (repeat measures analysis of variance); the Dialysis Living Will and Centre for Bioethics Living Will scored significantly higher than the Medical Directive). +1 more finding
Full summary, score breakdown and related studies → Original source
-
1995-11-01
Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia
54/100 ✓ Peer-reviewed Inflammation and the immune system Annals of neurology
Key finding: In a prospectively clinically characterized population of acquired immunodeficiency syndrome (AIDS) patients we investigated the relationship between the clinical syndrome of HIV-associated dementia and the presence and relative quantity of immunocytochemical markers for HIV-1 (gp41 antibody), and for macrophages and microglia (HAM-56 antibody). +3 more findings
Full summary, score breakdown and related studies → Original source
-
1995-11-01
Apolipoprotein E allele epsilon 4, dementia, and cognitive decline in a population sample
57/100 ✓ Peer-reviewed Brain tissue and pathology Lancet (London, England)
Key finding: A population sample of persons aged 70 years and over was interviewed in 1990-91 to ascertain the presence of dementia or cognitive impairment. +3 more findings
Full summary, score breakdown and related studies → Original source
-
1995-11-01
Amyloid beta peptide potentiates cytokine secretion by interleukin-1 beta-activated human astrocytoma cells
41/100 ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America
Key finding: Recent descriptions of in vitro neurotoxic effects of A beta support this hypothesis and suggest toxicity might be mediated by A beta-induced neuronal calcium disregulation. +3 more findings
Full summary, score breakdown and related studies → Original source
-
1995-11-01
Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins
49/100 ✓ Peer-reviewed Risk genes beyond APOE Neuron
Key finding: Age at onset of neophobia and age at death decrease with increasing levels of brain APP. +3 more findings
Full summary, score breakdown and related studies → Original source
-
1995-11-01
Excessive glutamine sensitivity in Alzheimer's disease and Down syndrome lymphocytes
33/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of the neurological sciences
Key finding: A highly significant decrease in mitotic index in the presence of exogenous glutamine was noted in patients presenting an Alzheimer type dementia with or without associated Down syndrome. +2 more findings
Full summary, score breakdown and related studies → Original source
-
1995-11-01
Apolipoprotein E, dementia, and cortical deposition of beta-amyloid protein
59/100 ✓ Peer-reviewed How common it is The New England journal of medicine
Key finding: Even in elderly subjects without dementia, the apolipoprotein E genotype is related to the degree of deposition of beta-amyloid protein in the cerebral cortex. +1 more finding
Full summary, score breakdown and related studies → Original source
-
1995-11-01
Pain in cognitively impaired nursing home patients
53/100 ✓ Peer-reviewed How common it is Journal of pain and symptom management
Key finding: Subjects demonstrated substantial cognitive impairment (mean Folstein Mini-Mental State exam score was 12.1 +/- 7.9), typically having deficits in memory, orientation, and visual spatial skills. +1 more finding
Full summary, score breakdown and related studies → Original source
October 1995 4
-
1995-10-01
Prevalence of Alzheimer's disease and dementia in two communities: Nigerian Africans and African Americans
50/100 ✓ Peer-reviewed Health systems and care delivery The American journal of psychiatry
Key finding: The age-adjusted prevalence rates of dementia (2.29%) and Alzheimer's disease (1.41%) in the Ibadan sample were significantly lower than those in the Indianapolis sample, both in the community-dwelling subjects alone (4.82% and 3.69%, respectively) and in the combined nursing home and community samples (8.24% and 6.24%, respectively). +1 more finding
Full summary, score breakdown and related studies → Original source
-
1995-10-01
Neuropathological diagnostic criteria for Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases)
36/100 ✓ Peer-reviewed Risk factors Brain pathology (Zurich, Switzerland)
Key finding: This spongiform change is characterised by diffuse or focally clustered small round or oval vacuoles in the neuropil of the deep cortical layers, cerebellar cortex or subcortical grey matter, which might become confluent. +4 more findings
Full summary, score breakdown and related studies → Original source
-
1995-10-01
Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo
40/100 ✓ Peer-reviewed Treatments Neuropharmacology
Key finding: The data from the present study do not lend support to the idea that low affinity, open channel NMDA receptor blockers are also effective in models of epilepsy at doses having little effect on physiological processes. +4 more findings
Full summary, score breakdown and related studies → Original source
-
1995-10-01
Tau, ubiquitin, and alpha B-crystallin immunohistochemistry define the principal causes of degenerative frontotemporal dementia
43/100 ✓ Peer-reviewed Drug development Archives of neurology
Key finding: These findings indicate that immunostaining with these antibodies is essential for the evaluation of frontal dementia. +1 more finding
Full summary, score breakdown and related studies → Original source
Browse the library by subject, with the full score breakdown →