Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

This page is alzhub.org's plain-English summary of a published study, not the paper itself. It is generated from the record we hold for this study, sourced and linked below — check the original for the full text and methods.

✓ Peer-reviewed alzhub usefulness score 27 out of 100. Down syndrome and Alzheimer's

Topic: Risk, prevention and care in population studies

Para psychotic troubles in Mentally Handicapped Persons (particularly in Down syndrome)-Clinical examples of M.H.P. which had no trouble until their 25-40 (years) except their intellectual defect and then, slide in psychiatric or para psychiatric behaviour. It starts with loosing vital aim and long lasting soliloquy. Then starting with an emotional frustration. Special reflexion about pseudo intellectual deterioration considered as, almost Alzheimer which is often a kind of familial contage of loosing vital impulse. It seems obvious for M.H.P. that realising their handicap without being prepared nor psychologically accompanied lead a possible trigger for loosing psychological control. Sports or leisure activities with other M.H.P. are most inefficient but a prevention often appears possible.

Key findings

Why it matters

This clinical report describes psychiatric and behavioural changes in adults with intellectual disability, particularly Down syndrome, and mentions pseudo intellectual deterioration sometimes considered almost Alzheimer-like. It offers observations and thoughts on prevention of psychological loss of control, not any treatment, cure or prevention for Alzheimer's disease.

Study details

How this study scored 27/100
How this study's score is builtJournal tier 7 of 10; Journal's citation record left out, no data; Study design 0 of 12; Strength of evidence 1 of 5; Peer-review validation 10 of 10; How recent 1 of 5; Sample size 0 of 4; Effect reported 0 of 3; Studied in people 0 of 3; Randomised / blinded 0 of 2; Times cited 1 of 7; Citations per year 0 of 5; Impact for its field and year left out, no data; Cited by studies here 0 of 6; Still being cited 0 of 4; Senior author's track record left out, no data; Institution's track record left out, no data; Multi-centre collaboration 0 of 3; Indexed in PubMed 2 of 2; Free to read 0 of 2. 22 of the 83 points it could be judged on, which is 27 of 100. Total 27 of 100.22 of the 83 points we could judge = 27 of 100

Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on journal's citation record, impact for its field and year, senior author's track record and institution's track record, so those were left out: it earned 22 of the 83 points we could judge it on, which is 27 out of 100.

ComponentPointsWhy
Journal tier 7 / 10 Tier 3 — peer-reviewed journal (Annales medico-psychologiques)
Journal's citation record — / 4 No journal record from OpenAlex — left out of this score
Study design 0 / 12 No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence 1 / 5 Rated “low” in our summary
Peer-review validation 10 / 10 Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent 1 / 5 1995 — older than 20 years, still counted
Sample size 0 / 4 Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported 0 / 3 No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people 0 / 3 Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomised / blinded 0 / 2 No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited 1 / 7 Cited 1 times (OpenAlex, 2026-10-10)
Citations per year 0 / 5 0.0 citations a year over 33 year(s) since 1995
Impact for its field and year — / 6 No field-weighted citation impact (OpenAlex has none yet) — left out of this score
Cited by studies here 0 / 6 No other study in this library cites it
Still being cited 0 / 4 Cited 0 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record — / 4 Senior author's record not available — left out of this score
Institution's track record — / 3 No institution listed in OpenAlex — left out of this score
Multi-centre collaboration 0 / 3 OpenAlex lists 0 institution(s) in 0 countries — scores zero (affiliation lists can be incomplete)
Indexed in PubMed 2 / 2 Indexed in PubMed (PMID 8720368)
Free to read 0 / 2 Behind a paywall — scores zero
Points 22 / 83 Scored on 16 of 20 parts. We have no data for the rest, so they are left out: 22 of the 83 points we could judge it on is 27 out of 100.
Total 27 / 100 —

What each of these 20 components measures, and what this score is not →

Read the original

May need a subscription OpenAlex found no free copy of the full text (checked 6 Feb 1020), so the publisher may charge for it. The PubMed abstract is free.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

Built from the record alzhub holds for this paper, not looked up. This record has no DOI, so the citation leaves it out. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.

APA 7th

Lécuyer, R. (1995). [Parapsychotic disorders in mentally handicapped (particularly in Down's syndrome)]. Annales medico-psychologiques.

Vancouver

Lécuyer R. [Parapsychotic disorders in mentally handicapped (particularly in Down's syndrome)]. Annales medico-psychologiques. 1995. PMID: 8720368.

BibTeX

@article{lecuyer1995-8720368,
  author  = {Lécuyer, R.},
  title   = {{[Parapsychotic disorders in mentally handicapped (particularly in Down's syndrome)]}},
  journal = {Annales medico-psychologiques},
  year    = {1995},
  pmid    = {8720368}
}

Related studies in Down syndrome and Alzheimer's

Similar studies

More on Down syndrome and Alzheimer's

See all studies in Down syndrome and Alzheimer's →