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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 25,176–25,200 of 27,380 studies, newest first · page 1008 of 1096.

May 2001 14

  1. 2001-05-01

    Mitochondrial abnormalities in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: The finding that oxidative damage, including that to nucleic acids, in Alzheimer's disease is primarily limited to the cytoplasm of susceptible neuronal populations suggests that mitochondrial abnormalities might be part of the spectrum of chronic oxidative stress of Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2001-05-01

    Sundowning and circadian rhythms in Alzheimer's disease

    ✓ Peer-reviewed Risk factors The American journal of psychiatry

    Key finding: These data indicate that Alzheimer's disease causes disturbances of circadian rhythms and that sundowning is related to a phase delay of body temperature caused by Alzheimer's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2001-05-01

    Protection against beta-amyloid peptide toxicity in vivo with long-term administration of ferulic acid

    ✓ Peer-reviewed Biomarkers British journal of pharmacology

    Key finding: These results demonstrate that long-term administration of ferulic acid induces resistance to A beta 1-42 toxicity in the brain, and suggest that ferulic acid may be a useful chemopreventive agent against Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  4. 2001-05-01

    Both total and phosphorylated tau are increased in Alzheimer's disease

    ✓ Peer-reviewed Vascular contributions Journal of neurology, neurosurgery, and psychiatry

    Key finding: Both CSF tau and CSF phosphotau were increased in probable AD compared with FTD (p<0.001), SAE (p<0.001), PD (p<0.001), and controls (p<0.001). +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2001-05-01

    Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry

    ✓ Peer-reviewed Disease mechanisms Journal of neurochemistry

    Key finding: The results demonstrate: (1) a dramatic decrease in plasmalogen content (up to 40 mol% of total plasmalogen) in white matter at a very early stage of AD (i.e. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2001-05-01

    White matter damage is associated with matrix metalloproteinases in vascular dementia

    ✓ Peer-reviewed Inflammation and the immune system Stroke

    Key finding: Vascular disease causes multi-infarct dementia (MID) or Binswanger's disease (BD), the latter of which is a progressive form of vascular dementia (VaD) associated pathologically with fibrinoid and hyaline changes in brain arterioles with injury to the white matter. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2001-05-01

    Reducing delirium after hip fracture: a randomized trial

    ✓ Peer-reviewed Cognitive tests and assessment Journal of the American Geriatrics Society

    Key finding: Delirium (or acute confusional state) affects 35% to 65% of patients after hip-fracture repair, and has been independently associated with poor functional recovery. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2001-05-01

    TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice

    ✓ Peer-reviewed Risk genes beyond APOE Nature medicine

    Key finding: Transforming growth factor beta1 (TGF-beta1), a key regulator of the brain's responses to injury and inflammation, has been implicated in Abeta deposition in vivo. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2001-05-01

    Practice parameter: early detection of dementia: mild cognitive impairment (an evidence-based review) [RETIRED]. Report of the Quality Standards Subcommittee of the American Academy of Neurology

    ✓ Peer-reviewed Mild cognitive impairment Neurology

    Key finding: There were insufficient data to make any recommendations regarding cognitive screening of asymptomatic individuals. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2001-05-01

    Practice parameter: management of dementia (an evidence-based review) [RETIRED]. Report of the Quality Standards Subcommittee of the American Academy of Neurology

    ✓ Peer-reviewed Caregiving Neurology

    Key finding: Cholinesterase inhibitors benefit patients with AD (Standard), although the average benefit appears small; vitamin E likely delays the time to clinical worsening (Guideline); selegiline, other antioxidants, anti-inflammatories, and estrogen require further study.

    Full summary, score breakdown and related studies → Original source

  11. 2001-05-01

    Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: Diagnostic criteria for dementia have improved since the 1994 practice parameter. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2001-05-01

    Intensive Care Delirium Screening Checklist: evaluation of a new screening tool

    ✓ Peer-reviewed Getting a diagnosis Intensive care medicine

    Key finding: This study suggests that the Intensive Care Delirium Screening Checklist can easily be applied by a clinician or a nurse in a busy critical care setting to screen all patients even when communication is compromised. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2001-05-01

    Antihypertensive drugs and incidence of dementia: the Rotterdam Study

    ✓ Peer-reviewed Prevention and risk Neurobiology of aging

    Key finding: For Alzheimer's disease the relative risk was 0.87, not significant.

    Full summary, score breakdown and related studies → Original source

  14. 2001-05-01

    Vitamin B(12) and folate in relation to the development of Alzheimer's disease

    ✓ Peer-reviewed Prevention and risk Neurology

    Key finding: A population-based longitudinal study in Sweden, the Kungsholmen Project A random sample of 370 nondemented persons, aged 75 years and older and not treated with B(12) and folate, was followed for 3 years to detect incident AD cases.

    Full summary, score breakdown and related studies → Original source

April 2001 11

  1. 2001-04-20

    Few Alzheimer’s Patients Get State-of-Art Care

    ✓ Peer-reviewed Risk factors Psychiatric News

    Key finding: Back to table of contents Previous article Next article Clinical & Research NewsFull AccessFew Alzheimer’s Patients Get State-of-Art CareJim RosackJim RosackSearch for more papers by this authorPublished Online:20 Apr 2001https://doi.org/10.1176/pn.36.8.0042Preliminary data suggest that a huge treatment gap exists in patients with Alzheimer’s disease, with as many as 65 percent of patients with the progressive and terminal disorder going undiagnosed and, therefore, untreated. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2001-04-17

    Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Our results demonstrate that cholesterol reduction promotes the nonamyloidogenic alpha-secretase pathway and the formation of neuroprotective alpha-secretase cleaved soluble APP by several mechanisms and suggest approaches to prevention of or therapy for Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  3. 2001-04-10

    Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

    ✓ Peer-reviewed How common it is Proceedings of the National Academy of Sciences of the United States of America

    Key finding: These results suggest that lipids are playing an important role in the development of Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  4. 2001-04-01

    Childhood socioeconomic position and cognitive function in adulthood

    ✓ Peer-reviewed Disparities International journal of epidemiology

    Key finding: Higher SEP during childhood and greater educational attainment are both associated with cognitive function in adulthood, with mothers and fathers each contributing to their offspring's formative cognitive development and later life cognitive ability (albeit in different ways). +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2001-04-01

    Patterns of temporal lobe atrophy in semantic dementia and Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: Semantic dementia and Alzheimer's disease groups did not differ significantly on global atrophy measures. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2001-04-01

    Cholesterol metabolism in the brain

    ✓ Peer-reviewed Genetics Current opinion in lipidology

    Key finding: Indirect evidence suggests that large amounts of cholesterol also turn over among the glial cells and neurons within the central nervous system during brain growth and neuron repair and remodelling.

    Full summary, score breakdown and related studies → Original source

  7. 2001-04-01

    Cerebrovascular and brain morphologic correlates of mild cognitive impairment in the National Heart, Lung, and Blood Institute Twin Study

    ✓ Peer-reviewed Vascular contributions Archives of neurology

    Key finding: Elevated midlife blood pressures, and the resulting increased white matter hyperintensities, increase the risk for MCI in a group of community-dwelling older men to at least the same degree as apolipoprotein E4 genotype. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2001-04-01

    Amygdala and hippocampal volumes in children with Down syndrome: a high-resolution MRI study

    ✓ Peer-reviewed Hippocampus size on brain scans Neurology

    Key finding: The objective of this study was to use high-resolution MRI techniques to determine whether children with Down syndrome exhibit decreases in hippocampal and amygdala volumes similar to those demonstrated in recent studies of adults with this condition. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2001-04-01

    Psychiatric illness and mortality after hip fracture

    ✓ Peer-reviewed Clinical safety Lancet (London, England)

    Key finding: We found that dementia, delirium, and depression all increased the risk of mortality (p<0.0001, p<0.0001, and p=0.0359, respectively), and that mortality differed significantly between hospitals (p=0.0003). +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2001-04-01

    Familial amyotrophic lateral sclerosis and parkinsonism-dementia complex of the Kii Peninsula of Japan: clinical and neuropathological study and tau analysis

    ✓ Peer-reviewed Disease mechanisms Annals of neurology

    Key finding: Neurofibrillary tangles exhibited twisted tubule structures on electon microscopic examination, and an analysis of insoluble tau protein extracted from the fresh brain revealed a 60-, 64-, 68-kD triplet. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2001-04-01

    Alzheimer's Disease: Genes, Proteins, and Therapy

    ✓ Peer-reviewed Disease mechanisms Physiological Reviews

    Key finding: All four genes definitively linked to inherited forms of the disease to date have been shown to increase the production and/or deposition of amyloid beta-protein in the brain. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →