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prospective
1,139 studies tagged prospective, dated 1978-04-01 to 2026-09-26. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Public awareness of the hearing loss-dementia link and self-reported behavioral changes in middle- to older-aged Canadians 2026-09-26
- Patterns of modifiable lifestyle, behavioural and health-related risk factors and their associations with incident dementia in UK Biobank 2026-09-25
- Excess hypoglycaemia-related hospitalisation in older adults with comorbid type 2 diabetes and dementia: a UK Biobank cohort study 2026-09-16
Studies
1,139 studies carry this tag.
Date range
1978 to 2026
Top journals
- Neurology 134
- Alzheimer s & Dementia 52
- Alzheimer's & dementia : the journal of the Alzheimer's Association 33
- Journal of the American Geriatrics Society 32
- JAMA neurology 27
362 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Individuals with both physical frailty and depression had the highest risk of dementia.
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All the five dimensional SDOH disadvantages were significantly associated with higher odds of both dementia and MCI in the overall sample (p <0.05) (Figure 1).
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55/100
Among 24 762 people with HIV and 494 963 people without HIV (86.9% men, 45.5% White, 23.1% Black, 20.3% Hispanic), incident dementia diagnoses declined from 2000 to 2023 in both people with and without HIV (-7.68 and -2.70% per period, respectively).
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45/100
When systematically reviewed using the USDA Nutrition Evidence Systematic Review method and an a priori established protocol, a common theme emerged: diets characterized by higher consumption of vegetables, fruits, legumes, nuts, fish, seafood, and unsaturated vegetable oils, alongside lower intake of red and processed meats and sugar-sweetened beverages, are consistently associated with a reduced risk of cognitive decline and dementia.
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Sample characteristics are shown in Table 1.
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Dream recall status was associated with blood p ‐tau217 levels, APOE ε4 carriage, and future cognitive decline among older individuals cognitively healthy at baseline.
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Among the 18,013 participants with complete data for analysis, 516 (2.86%) exhibited cognitive impairment.
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Residing in neighborhoods characterized by low-income, low-vehicle access, and higher low-fat milk prices was associated with a greater risk of incident dementia.
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105 participants (47 Latino, 55 Black), 64.7 (±8.8) years-old, female 66 (63%), with 16 (±2.3) years of education were assessed.
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When risk factors were evaluated independently, we found less early-life education, mid-life hearing loss and diabetes, and late-life social isolation and visual loss associated with increased odds for dementia.
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55/100
Between Sept 1, 2017, and Feb 28, 2019, 19 403 individuals were invited to participate and 9745 participants (1525 with dementia, 8220 without dementia) were included. 4445 (45·6%) of 9745 participants were male and 5300 (54·4%) were female.
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Among 160 centenarians, 63.7% did not meet the PCFP criteria and were classified as having dementia.
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(n = 399) have completed the first follow-up assessments, including MoCA, mCAIDE, memory self-report, demographic information.
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In highly segregated counties, Black older adults with elevated CVD demonstrated worse memory than those with lower CVD; in less segregated counties, memory levels did not differ by CVD.
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Diagnostic classifications, mean age, and education did not differ significantly across classifications.
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Older adults in rural India experience higher social isolation due to limited social and healthcare resources.
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117 participants have complete data (mean age: 73 ± 7.4).
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In adults aged ≥65 years, dementia with CAD was the cause of 1,256,284 deaths between 1999 and 2023.
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Type 2 diabetes mellitus (T2DM) is associated with poorer cognitive performance and increased dementia risk.
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Income was among the top risk factors for all three groups.
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There were observable geographic variations in education (range 13.4-16.2 years, Figure 1), age (range 66.7-72.4 years) and severable modifiable risk factors for dementia across Tasmania, Australia.
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(1) To investigate the association between age at diabetes diagnosis and the incidence of all-cause dementia (ACD), Alzheimer’s disease (AD), and vascular dementia (VD) in individuals with diabetes.
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Keeping current with the burden and risk factors of Alzheimer disease and other dementias (ADOD) from global to national levels is critical for healthcare planning, prevention strategies, and the allocation of resources.
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Over 13.45 years, 992 all-cause dementia cases were recorded.
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In 2021, LOAD demonstrated a substantially higher global burden than EOAD: incidence cases (8,455,150 [95% UI: 5,818,063-11,461,560] vs. 1,381,906 [894,768-1,963,453]), mortality cases (1,879,291 [471,472-4,968,222] vs. 73,386 [14,059-232,170]), and DALYs (32,558,570 [14,907,368-71,154,572] vs. 3,774,117 [1,696,439-8,881,154]).
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In ARIC (n = 1,736, mean age 63, 58.8% female, 48.7% non-Hispanic White individuals, median follow-up 18.6 years), the dementia incidence rate was 10.4 (95% CI, 9.2-11.6) per 1,000 person-years.
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62/100
This study included 1526 early adult-life (mean [SD] age, 36.7 [4.7] years; 821 [53.8%] female), 1943 midlife (mean [SD] age, 54.0 [5.8] years; 1010 [52.0%] female), and 885 late-life (mean [SD] age, 71.0 [4.5] years; 473 [53.4%] female) participants.
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Anemia among older adults aged ≥ 60 years is a well-described risk factor that increases the risk of falls, cardiovascular diseases, and mortality.
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Predictive performance was comparable across algorithms, with R² ranging from 0.201 to 0.361, highest in the MCI_All dataset.
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There were 13,145 individuals with risk factor data between 2015 and 2018 (51.1% aged 18-44, 31.0% aged 45-64, and 17.9% aged ≥65 years; 51.5% female after survey-weighting).
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Participants showed a significantly slower rate of cognitive decline than expected from the AD reference rate (p < 0.001), with many demonstrating stabilized ADAS-Cog scores during their respective treatment periods, ranging from 1 to 3 years.
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Sample 1 included 1656 participants (mean [range] age, 58.1 [29.7-85.6] years; 903 female [54.5%]), and sample 2 included 935 participants (mean [range] age, 67.6 [60.0-85.6] years; 518 female [55.4%]).
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Zinc deficiency represents an independent, modifiable risk factor for new-onset dementia with a clear dose-response relationship.
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During a mean follow-up of 2.49 years (median, 1.99; standard deviation, 2.07; interquartile range, 2.66), dementia was significantly associated with increased stroke risk (aHR, 3.19; 95% confidence interval, 2.84-3.57).
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44/100
The heart rate response/recovery (HRR) index, a common indicator for cardiovascular health during exercise, has been linked with neurocognitive disorders and mortality.
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Each 1-unit increase in cumulative score was associated with a 3%-8% higher dementia hazard across cohorts.
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all-cause mortality, stroke recurrence, cognition, and C-reactive protein (CRP).
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In the UK Biobank cohort (N = 166,916), MIND diet demonstrated the broadest neuroprotective effects.
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Adult vaccinations, particularly against herpes zoster, influenza, pneumococcus and Tdap, are associated with a lower risk of dementia.
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BackgroundAccurate and accessible risk assessment tools are essential for effective dementia management.
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Study 1 showed that each person's financial strain was associated with their own greater depressive symptoms.
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After PSM, 7914 participants were analyzed (3957 consumers; 3957 non-consumers).
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This study aimed to investigate the bidirectional causal relationship between celiac disease (CD) and the risk of Alzheimer disease (AD) or frontotemporal dementia (FTD) using Mendelian randomization (MR), in order to clarify prior inconsistent findings.
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51/100
Elevated FSH and reduced LH may be associated with poorer cognition and an increased risk of AD-D in very old Chinese adults, particularly in males.
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Place-based SDoH measures were higher in Black compared to White participants.
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Our findings highlight the importance of personalized risk assessments and the development of tailored interventions based on genetic background to prevent dementia more effectively.
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Dementia incidence was 0.89 per 1000 person-years.
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This meta-analysis highlights sleep management as a pivotal modifiable factor in reducing the risk of all-cause cognitive decline.
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Diabetes is a global health concern associated with complications such as cognitive decline and dementia.
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A total of 9,656 (13.5%) participants had at least 1 CMD at baseline.
From across this tag
10 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Social isolation and loneliness as modifiable risk factors for dementia: Evidence-based interventions and public health implications
- Peripheral immunity is associated with the risk of incident dementia
- Association between zinc deficiency and adverse outcomes in patients with dementia: a matched cohort study
- CIND and MCI in the Italian elderly: frequency, vascular risk factors, progression to dementia
- Residential exposure to road and railway traffic noise and incidence of dementia: The UK Biobank cohort study
- Patterns of modifiable lifestyle, behavioural and health-related risk factors and their associations with incident dementia in UK Biobank
- Relation between smoking and risk of dementia and Alzheimer disease: the Rotterdam Study
- Risk factors for incident dementia in England and Wales: The Medical Research Council Cognitive Function and Ageing Study. A population-based nested case-control study
- Sleep Apnea as a Modifiable Risk Factor for Cognitive Decline and Dementia: Implications for Clinical Practice and Public Health
- Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study