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Relationships among cognitive function, ADRD risk and sociodemographic characteristics in a diverse rural setting in south‐central Florida
Christine L. Williams, Lisa Kirk Wiese, Janet K. Holt, Lilah M. Besser. Alzheimer s & Dementia, 2025-12-01
Topic: Risk, prevention and care in population studies
Participants (n = 399) have completed the first follow-up assessments, including MoCA, mCAIDE, memory self-report, demographic information. Most identified as female (287, 72%). Ethnic group membership included Black (311, 78%), White (74, 19%), Hispanic/Latino (61, 15%), Afro-Caribbean (12, 3%) and 14 (4%) reported other race(s). Median age was 64 years, with 12 years of education and residence in study communities, 50 years. Notably, 203 (51%) had MoCA scores of 26+, while 150 (38%) reported memory decline. None of the covariates predicted subjective memory decline, p .05). Of the 359 participants with relevant data, age (p .05). Approximately half the participants are at-risk for ADRD based on MoCA scores. Although participants with more education and/or Hispanic/Latino ethnicity experienced less ADRD risk, there is a need to identify environmental factors that cognitive decline among rural residents.
Key findings
- Participants (n = 399) have completed the first follow-up assessments, including MoCA, mCAIDE, memory self-report, demographic information.
- Ethnic group membership included Black (311, 78%), White (74, 19%), Hispanic/Latino (61, 15%), Afro-Caribbean (12, 3%) and 14 (4%) reported other race(s).
- Median age was 64 years, with 12 years of education and residence in study communities, 50 years.
- Notably, 203 (51%) had MoCA scores of 26+, while 150 (38%) reported memory decline.
- None of the covariates predicted subjective memory decline, p .05).
Why it matters
This study describes cognitive test scores, memory concerns, and demographic factors in a diverse rural Florida population, finding about half were at risk for Alzheimer's disease based on test scores. It does not test any treatment, cure, or prevention.
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Study details
- Participants399
- Evidence strengthLow
How this study scored 37/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Alzheimer s & Dementia) |
| Journal's citation record | 2 / 4 | Alzheimer s & Dementia: journal h-index 228 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 2 / 4 | 399 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 0 / 7 | Cited 0 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.0 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 0 / 6 | Cited 0.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 0 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Lilah M. Besser: h-index 34 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | University of Miami: institution h-index 998 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 41434296) |
| Free to read | 2 / 2 | Free to read |
| Total | 37 / 100 | — |
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Read the original
- DOI: 10.1002/alz70860_101721
- PubMed: 41434296
- Original source →
- Free full text: Alzheimer s & Dementia →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
APA 7th
Williams, C. L., Wiese, L. K., Holt, J. K., & Besser, L. M. (2025). Relationships among cognitive function, ADRD risk and sociodemographic characteristics in a diverse rural setting in south‐central Florida. Alzheimer s & Dementia. https://doi.org/10.1002/alz70860_101721
Vancouver
Williams CL, Wiese LK, Holt JK, Besser LM. Relationships among cognitive function, ADRD risk and sociodemographic characteristics in a diverse rural setting in south‐central Florida. Alzheimer s & Dementia. 2025. doi:10.1002/alz70860_101721. PMID: 41434296.
BibTeX
@article{williams2025-41434296,
author = {Williams, Christine L. and Wiese, Lisa Kirk and Holt, Janet K. and Besser, Lilah M.},
title = {{Relationships among cognitive function, ADRD risk and sociodemographic characteristics in a diverse rural setting in south‐central Florida}},
journal = {Alzheimer s \& Dementia},
year = {2025},
doi = {10.1002/alz70860_101721},
pmid = {41434296},
url = {https://doi.org/10.1002/alz70860_101721}
}
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