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Associations of Individual Beverage Types and Substitution with Dementia Risk: A UK Biobank Cohort Study
Jung-Hwan Kim, Yu‐Jin Kwon, Yaeji Lee, Taehwa Han, Mi Young Lim, Seok‐Jae Heo, Ji‐Won Lee. The journal of nutrition health & aging, 2025-11-27
Topic: Risk, prevention and care in population studies
Over 13.45 years, 992 all-cause dementia cases were recorded. Higher sugar-sweetened beverage intake (>1 glass/day) was associated with an increased risk of all-cause dementia (HR, 1.61; 95% CI, 1.28-2.02; P < 0.001). Coffee and tea consumption were associated with a lower risk of all-cause dementia. Substituting sugar-sweetened beverages or artificially sweetened beverages with coffee or tea significantly reduced the risk of all-cause dementia. These protective associations were strongest among individuals with obesity, hypertension, depression, or dyslipidemia. Replacing sugar-sweetened beverages or artificially sweetened beverages with coffee or tea was associated with a reduced risk of dementia, particularly among individuals with modifiable risk factors. These findings support beverage substitution as a simple, targeted strategy for mitigating the risk of dementia.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Kim, J.-H., Kwon, Y., Lee, Y., Han, T., Lim, M. Y., Heo, S., et al. (2025). Associations of Individual Beverage Types and Substitution with Dementia Risk: A UK Biobank Cohort Study. The journal of nutrition health & aging. https://doi.org/10.1016/j.jnha.2025.100740
Vancouver
Kim J.-H, Kwon Y, Lee Y, Han T, Lim MY, Heo S, et al. Associations of Individual Beverage Types and Substitution with Dementia Risk: A UK Biobank Cohort Study. The journal of nutrition health & aging. 2025. doi:10.1016/j.jnha.2025.100740. PMID: 41314057.
BibTeX
@article{kim2025-41314057,
author = {Kim, Jung-Hwan and Kwon, Yu‐Jin and Lee, Yaeji and Han, Taehwa and Lim, Mi Young and Heo, Seok‐Jae and Lee, Ji‐Won},
title = {{Associations of Individual Beverage Types and Substitution with Dementia Risk: A UK Biobank Cohort Study}},
journal = {The journal of nutrition health \& aging},
year = {2025},
doi = {10.1016/j.jnha.2025.100740},
pmid = {41314057},
url = {https://doi.org/10.1016/j.jnha.2025.100740}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
Key findings
- Over 13.45 years, 992 all-cause dementia cases were recorded.
- Higher sugar-sweetened beverage intake (>1 glass/day) was associated with an increased risk of all-cause dementia (HR, 1.61; 95% CI, 1.28-2.02; P < 0.001).
- Coffee and tea consumption were associated with a lower risk of all-cause dementia.
- Substituting sugar-sweetened beverages or artificially sweetened beverages with coffee or tea significantly reduced the risk of all-cause dementia.
- These protective associations were strongest among individuals with obesity, hypertension, depression, or dyslipidemia.
Why it matters
In this UK Biobank cohort, drinking more than one glass a day of sugar-sweetened beverages was linked to higher dementia risk, while coffee and tea were linked to lower risk, and substituting coffee or tea for these beverages was linked to reduced risk. The authors support beverage substitution as a possible targeted strategy, but the study is observational and does not prove cause and effect.
Study details
- Study designcohort study
- Participants118,963
- Evidence strengthModerate
How this study scored 52/100
Published in a peer-reviewed journal, and it is a cohort study following people over time. Scored zero for effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (The journal of nutrition health & aging) |
| Journal's citation record | 1 / 4 | The journal of nutrition health & aging: journal h-index 122 (OpenAlex, 2026-10-29) |
| Study design | 7 / 12 | A cohort study following people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 4 / 4 | 118,963 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 2 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.7 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 2 / 6 | Cited 1.3× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 2 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Ji‐Won Lee: h-index 51 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Yonsei University: institution h-index 777 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 5 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 41314057) |
| Free to read | 2 / 2 | Free to read |
| Total | 52 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/j.jnha.2025.100740
- PubMed: 41314057
- Original source →
- Free full text: The journal of nutrition health & aging →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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