Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Alzheimer disease (AD) is a disorder of the nervous system that mostly impacts the brain cells and causes the slow destruction of the brain.
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Isolated rapid eye movement sleep behaviour disorder (iRBD) strongly predicts future Lewy body disease and identifies a more aggressive, non-motor phenotype in Parkinson’s disease (PD).
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According to the AT(N) framework, Alzheimers disease (AD) can be biologically characterised by amyloid deposition, tau pathology, and neurodegeneration, yet how these processes relate to whole-brain dynamics remains unclear.
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Resting-state EEG is a scalable modality for neurophysiological screening, but conventional spectral descriptors capture only part of the signal organization altered in neurodegenerative disease.
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Electroencephalography (EEG) records cortical activity with high temporal resolution without radiation and at low cost, which makes it a practical signal for automated screening of neurological disorders.
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The upper cervical spinal cord is essential for motor, sensory and autonomic function, yet its normative morphometric trajectories and disease-related deviations remain unclear.
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Standardized cognitive and functional assessments, such as those in the National Alzheimer’s Coordinating Center (NACC) Uniform Data Set (UDS), are central to detecting and monitoring Alzheimer’s disease, yet their administration and scoring depend on trained examiners who record and score responses by hand.
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The choroid plexus (ChP) is a highly vascularized structure located in the brain ventricles that plays important roles in multiple central nervous system functions.
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A bstract Deep learning models for electroencephalography (EEG) pathology detection achieve competitive accuracy but offer limited interpretability.
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Unlike traditional eager decision trees (eagerDT), which lacked sufficient training data for 17%-33% of patient profiles, lazyDT-MCCPath successfully modeled all profiles and achieved a 0.17 improvement in AUROC (0.66 vs. 0.83). lazyDT-MCCPath effectively translates pre-existing MCC profiles into personalized dementia risk probabilities for emerging conditions, which may help clinicians prioritize MCCs to monitor more closely.
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For more than 150 years, since the idea that mental illness is rooted in the brain first emerged in the mid-1800s, psychiatry has searched for a reliable biological system to anchor its understanding of mental illness.
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Our results converge on the conclusion that vtaVNS does not uniformly amplify cortical responses to external stimuli.
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Symptom chronology emerged as a robust diagnostic discriminator, underscoring the clinical value of temporal disease trajectories.
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Machine learning (ML) methods have shown promise in modeling clinical trajectories associated with neurodegenerative disorders such as Alzheimer’s disease (AD).
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Prior work has demonstrated a link between cognitive impairment and financial vulnerability.
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Mean age was 59.6 years, and 57.8% were male.
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Vascular risk factors were associated with CSVD burden and progression, and WMH and PVS progression were further associated with cortical atrophy and cognitive decline, underscoring the interconnected contributions of vascular risk, CSVD, and neurodegeneration to cognitive aging and dementia risk.
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Model-inferred and reference diagnoses showed exact agreement rates from 18.8% to 56.2% with poor to slight chance-corrected agreement (Cohen’s κ = −.178 to .196).
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This study aimed to address these limitations by examining whether multilingual experience is associated with longitudinal ageing trajectories across objective and subjective measures spanning cognitive, affective, linguistic, and non-linguistic domains.
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The Alzheimer’s Disease Neuroimaging Initiative (ADNI) provides a comprehensive multimodal neuroimaging resource for studying aging and Alzheimer’s disease (AD).
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16/100
For more than 150 years, since the idea that mental illness is rooted in the brain first emerged in the mid-1800s, psychiatry has searched for a reliable biological system to anchor its understanding of mental illness.
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In this bvFTD cohort, structural volumes of key frontotemporal and perisylvian regions did not predict behavioral or language impairments after correction for multiple comparisons.
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Aging is characterized by normative changes in memory and a continued capacity for goal-directed learning and adaptation.
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Neuroimaging studies that pool data across clinical sites often suffer from site effects — variability in imaging measures that arises from technical heterogeneity across sites as opposed to true biological signal.
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Parkinson’s disease (PD) exhibits considerable variability in symptom onset, severity, and clinical trajectories, making prediction of individual disease progression a complex challenge.
From across this topic
10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Social factors that predict cognitive decline in older African American adults
- Functional connectivity and microstructural white matter changes in phenocopy frontotemporal dementia
- New Alzheimer’s Disease Diagnostics and Psychological Clinical Perspectives
- Altered cortical and subcortical local coherence in PTSD: evidence from resting-state fMRI
- Fast parallel image registration on CPU and GPU for diagnostic classification of Alzheimer's disease
- A Community-Based Study of Dementia in Mexican American and Non-Hispanic White Individuals
- Boston cognitive assessment (BOCA) - a comprehensive self-administered smartphone- and computer-based at-home test for longitudinal tracking of cognitive performance
- Plasma Proteomic Correlates of Cognitive Function in Older Adults From Central Africa
- A surface-based technique for warping three-dimensional images of the brain
- Memory-related EEG power and coherence reductions in mild Alzheimer's disease