Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Automatic classification of patients with Alzheimer's disease from structural MRI: a comparison of ten methods using the ADNI database

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. NeuroImage 2010-06-11 Brain scans and imaging

    Recently, several high dimensional classification methods have been proposed to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls (CN) based on T1-weighted MRI.

  2. Application and comparison of classification algorithms for recognition of Alzheimer's disease in electrical brain activity (EEG)

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of neuroscience methods 2006-12-06 Digital health tools

    The early detection of subjects with probable Alzheimer's disease (AD) is crucial for effective appliance of treatment strategies.

  3. The Lille apathy rating scale (LARS), a new instrument for detecting and quantifying apathy: validation in Parkinson's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of neurology, neurosurgery, and psychiatry 2006-05-01 Clinical safety

    Standard validity indices showed that the LARS is sensitive and capable of distinguishing between apathy and depression.

  4. Childhood socioeconomic position and cognitive function in adulthood

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. International journal of epidemiology 2001-04-01 Disparities

    Higher SEP during childhood and greater educational attainment are both associated with cognitive function in adulthood, with mothers and fathers each contributing to their offspring's formative cognitive development and later life cognitive ability (albeit in different ways).

  5. Norms for letter and category fluency: demographic corrections for age, education, and ethnicity

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Assessment 1999-06-01 Risk factors

    Letter and category fluency tasks are used to assess semantic knowledge, retrieval ability, and executive functioning.

  6. Dutch Normal-Pressure Hydrocephalus Study: randomized comparison of low- and medium-pressure shunts

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of neurosurgery 1998-03-01 Digital health tools

    Outcome was better for patients who had an LPV shunt than for those with an MPV shunt, although most differences were not statistically significant.

  7. Age-related cognitive decline and vision impairment affecting the detection of dementia syndrome in old age

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. The British journal of psychiatry : the journal of mental science 1997-11-01 Risk factors

    The considerable age effect requires the adaptation of cut-off values for old age.

  8. Dutch normal-pressure hydrocephalus study: prediction of outcome after shunting by resistance to outflow of cerebrospinal fluid

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of neurosurgery 1997-11-01 Digital health tools

    The authors examined whether measurement of resistance to outflow of cerebrospinal fluid (Rcsf) predicts outcome after shunting for patients with normal-pressure hydrocephalus (NPH).

  9. Visual hallucinations associated with Parkinson disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Archives of neurology 1996-12-01 Health systems and care delivery

    The phenomena of visual hallucinations associated with PD, while not fully explained, are unique enough to be of interest to all neurologists and neuroscientists.

  10. Effects of acute subcutaneous nicotine on attention, information processing and short-term memory in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Psychopharmacology 1992-01-01 Clinical trials

    This single-blind, placebo controlled study reports on the effects of administering three acute doses of nicotine (0.4, 0.6 and 0.8 mg) subcutaneously to a group of Alzheimer's disease (DAT) patients (n = 22), young adult controls (n = 24), and normal aged controls (n = 24).

  11. Computerized cognitive testing battery identifies mild cognitive impairment and mild dementia even in the presence of depressive symptoms

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. American journal of Alzheimer's disease and other dementias 2006-01-01 Cognitive tests and assessment

    Cognitive and depressive symptoms co-occur, complicating detection of mild cognitive impairment (MCI) and early dementia.

  12. Validity of the Mindstreams computerized cognitive battery for mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Journal of molecular neuroscience : MN 2004-01-01 Cognitive tests and assessment

    The NeuroTrax Mindstreams computerized cognitive assessment system was designed for widespread clinical and research use in detecting mild cognitive impairment (MCI).

  13. Obstructive Sleep Apnea and Aging: A Narrative Review

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Sleep medicine research 2025-09-29 Risk factors

    Obstructive sleep apnea is one of the most common sleep disorders.

  14. Smartphone Keystroke-based Cognitive Impairment Diagnostic Methodology

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2025-07 Cognitive tests and assessment

    With the global population rapidly aging, dementia has emerged as a major public health concern.

  15. Dementia in ancient Greece and Rome

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of Alzheimer's disease : JAD 2025-06-23 Risk factors

    We respond to the commentary by Ballenger et al. While appreciating "our provocative article", they called for "a more rigorous historical approach…".

  16. Personalized Multi-Domain Digital Platform for Dementia Prevention

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Studies in health technology and informatics 2025-02-18 Prevention trials

    The Personalized Multi-Domain Digital Platform for Dementia Prevention (PM(DP)*2) is a conceptualized evidence-based initiative designed to reduce dementia burden through tailored interventions.

  17. Tablet-based self assessment memory scale-revised (SAMS-R) evaluates memory functions for older adults

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Frontiers in aging neuroscience 2025-01-22 Cognitive tests and assessment

    The 2nd SAMS score were higher than the 1st SAMS score in some participants, on the other hand, the intraclass correlation coefficient was good.

  18. Default Mode Network Functional Connectivity As a Transdiagnostic Biomarker of Cognitive Function

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Biological psychiatry. Cognitive neuroscience and neuroimaging 2025-01-09 Brain scans and imaging

    The default mode network (DMN) is intricately linked with processes such as self-referential thinking, episodic memory recall, goal-directed cognition, self-projection, and theory of mind.

  19. A novel model for retinal imaging in the diagnosis of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. NPJ digital medicine 2025-01-09 Brain scans and imaging

    Alzheimer’s disease is the fifth-leading cause of death for adults over the age of 65.

  20. Hearing Loss and Alzheimer Disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Current topics in behavioral neurosciences 2025 Risk factors

    Several studies have been done to investigate the role of hearing loss (HL) in cognitive decline.

  21. The importance of cognitive correlates of plasma amyloid-β 42/40

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of Alzheimer's disease : JAD 2024-11-25 Biomarkers

    This commentary focuses on the clinical utility of plasma amyloid-β (Aβ) 42/40 to detect semantic intrusion errors in amnestic mild cognitive impairment, as investigated Curiel Cid et al. in a recent issue of the Journal of Alzheimer's Disease.

  22. Detecting functional impairment with the Digital Clock and Recall

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of Alzheimer's disease : JAD 2024-11-12 Cognitive tests and assessment

    The DCR scaled well with FAQ scores, and ML classifiers trained on multimodal DCR features demonstrated strong performance in predicting functional impairment on a held-out test set.

  23. Sex differences in the association between repetitive negative thinking and neurofilament light

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Npj mental health research 2024-11-11 Biomarkers

    Emerging evidence suggests that repetitive negative thinking (RNT; i.e., worry and ruminative brooding) is associated with biomarkers of Alzheimer's disease.

  24. [Senses and dementia : sensory loss and dementia risk]

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Revue medicale de Liege 2024-11 Risk factors

    In the course of several neurodegenerative conditions, the presence of a sensory alteration, even before the appearance of cognitive disorders or complaints concerning autonomy, can potentially lead to earlier diagnosis and more efficient management of these complex patients.

  25. New tablet-based screening tool for assessment of cognitive decline in Nigeria

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of Alzheimer's disease : JAD 2024-10-03 Cognitive tests and assessment

    We comment on the importance of the novel tablet-based screening tool for cognitive decline recently studied in Nigeria by Ogbuagu et al. TabCAT-BHA was administered on an iPad in urban and rural settings and was found to be a sensitive and culturally appropriate tool for assessing cognitive function and impairment.

From across this topic

10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

Other topics