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A Community-Based Study of Dementia in Mexican American and Non-Hispanic White Individuals
Lewis B Morgenstern, Emily M Briceño, Roshanak Mehdipanah, Wen Chang, Lisa Lewandowski-Romps, Xavier F Gonzales, Deborah A Levine, Kenneth M Langa et al.. Journal of Alzheimer's disease : JAD, 2024
Topic: Brain imaging, connectivity and assessment
Plain-language summary
1,901 participants completed the MoCA and 547 the HCAP. Mexican Americans were younger and had less educational attainment than non-Hispanic whites. Overall, dementia prevalence was 11.6% (95% CI 9.2-14.0) and MCI prevalence was 21.2% (95% CI 17.5-24.8). After adjusting for age, gender, and education level, there was no significant ethnic difference in the odds of dementia or MCI. Those with ≤11 compared with ≥16 years of education had much higher dementia [OR = 4.9 (95% CI 2.2-11.1)] and MCI risk [OR = 3.5 (95% CI 1.6-7.5)]. Dementia and MCI prevalence were high in both Mexican American and non-Hispanic white populations. Mexican American persons had double the odds of mild cognitive impairment and this was attenuated when age and educational attainment were considered. Educational attainment was a potent predictor of cognitive impairment.
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APA 7th
Morgenstern, L. B., Briceño, E. M., Mehdipanah, R., Chang, W., Lewandowski-Romps, L., Gonzales, X. F., et al. (2024). A Community-Based Study of Dementia in Mexican American and Non-Hispanic White Individuals. Journal of Alzheimer's disease : JAD. https://doi.org/10.3233/jad-230729
Vancouver
Morgenstern LB, Briceño EM, Mehdipanah R, Chang W, Lewandowski-Romps L, Gonzales XF, et al. A Community-Based Study of Dementia in Mexican American and Non-Hispanic White Individuals. Journal of Alzheimer's disease : JAD. 2024. doi:10.3233/jad-230729. PMID: 38143352.
BibTeX
@article{morgenstern2024-38143352,
author = {Morgenstern, Lewis B and Briceño, Emily M and Mehdipanah, Roshanak and Chang, Wen and Lewandowski-Romps, Lisa and Gonzales, Xavier F and Levine, Deborah A and Langa, Kenneth M and others},
title = {{A Community-Based Study of Dementia in Mexican American and Non-Hispanic White Individuals}},
journal = {Journal of Alzheimer's disease : JAD},
year = {2024},
doi = {10.3233/jad-230729},
pmid = {38143352},
url = {https://doi.org/10.3233/jad-230729}
}
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Key findings
- 1,901 participants completed the MoCA and 547 the HCAP.
- Mexican Americans were younger and had less educational attainment than non-Hispanic whites.
- Overall, dementia prevalence was 11.6% (95% CI 9.2-14.0) and MCI prevalence was 21.2% (95% CI 17.5-24.8).
- After adjusting for age, gender, and education level, there was no significant ethnic difference in the odds of dementia or MCI.
- Those with ≤11 compared with ≥16 years of education had much higher dementia [OR = 4.9 (95% CI 2.2-11.1)] and MCI risk [OR = 3.5 (95% CI 1.6-7.5)].
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Study details
- Study designcohort study
- Participants1,901
- Effect size11.6%; 21.2%; OR = 4.9 (95% CI 2.2-11.1)
- Evidence strengthModerate
How this study scored 75/100
Published in a peer-reviewed journal, and it is a cohort study following people over time. Scored zero for randomized / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multicenter collaboration and free to read, so those were left out: it earned 42 of the 56 points we could judge it on, which is 75 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of Alzheimer's disease : JAD) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 7 / 12 | A cohort study following people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2024 — within 3 year(s) of the newest study here |
| Sample size | 3 / 4 | 1,901 participants |
| Effect reported | 3 / 3 | Effect reported with a statistic (interval, p-value, ratio or similar) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multicenter collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 38143352) |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 42 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 42 of the 56 points we could judge it on is 75 out of 100. |
| Total | 75 / 100 | — |
What each of these 20 components measures, and what this score is not →
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