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Altered cortical and subcortical local coherence in PTSD: evidence from resting-state fMRI
Yuan Zhong, Ruiting Zhang, Kai Li, Rongfeng Qi, Zhiqiang Zhang, Qingling Huang, Guangming Lu. Acta Radiologica, 2015-06
Topic: Brain imaging, connectivity and assessment
Compared with the normal controls, PTSD patients showed increased local coherence in subcortical regions, including amygdala, hippocampus, thalamus, and putamen, and decreased local coherence in cortical regions, including medial prefrontal cortex and dorsolateral prefrontal cortex. Moreover, a correlation analysis of the ReHo measurement versus the severity of the disorder was performed, and highly positive correlation were observed in the right amygdala. The present study identified a functional discrepancy of local coherence between cortical and subcortical regions in PTSD patients compared with normal controls. The findings revealed that resting-state abnormalities might lead to further improvement of the understanding of the neural substrates of cognitive impairment and symptoms in PTSD.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Zhong, Y., Zhang, R., Li, K., Qi, R., Zhang, Z., Huang, Q., et al. (2015). Altered cortical and subcortical local coherence in PTSD: evidence from resting-state fMRI. Acta Radiologica. https://doi.org/10.1177/0284185114537927
Vancouver
Zhong Y, Zhang R, Li K, Qi R, Zhang Z, Huang Q, et al. Altered cortical and subcortical local coherence in PTSD: evidence from resting-state fMRI. Acta Radiologica. 2015. doi:10.1177/0284185114537927.
BibTeX
@article{zhong2015-4f9e1ece,
author = {Zhong, Yuan and Zhang, Ruiting and Li, Kai and Qi, Rongfeng and Zhang, Zhiqiang and Huang, Qingling and Lu, Guangming},
title = {{Altered cortical and subcortical local coherence in PTSD: evidence from resting-state fMRI}},
journal = {Acta Radiologica},
year = {2015},
doi = {10.1177/0284185114537927},
url = {https://doi.org/10.1177/0284185114537927}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
Key findings
- Compared with the normal controls, PTSD patients showed increased local coherence in subcortical regions, including amygdala, hippocampus, thalamus, and putamen, and decreased local coherence in cortical regions, including medial prefrontal cortex and dorsolateral prefrontal cortex.
- Moreover, a correlation analysis of the ReHo measurement versus the severity of the disorder was performed, and highly positive correlation were observed in the right amygdala.
- The present study identified a functional discrepancy of local coherence between cortical and subcortical regions in PTSD patients compared with normal controls.
- The findings revealed that resting-state abnormalities might lead to further improvement of the understanding of the neural substrates of cognitive impairment and symptoms in PTSD.
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Study details
- Evidence strengthLow
How this study scored 36/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 20 of the 56 points we could judge it on, which is 36 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Acta Radiologica) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2015 — within 20 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 1 / 2 | Not in PubMed, but has a DOI |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 20 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 20 of the 56 points we could judge it on is 36 out of 100. |
| Total | 36 / 100 | — |
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