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Brief Communication: Frailty and Neurocognitive Impairment in Older People Living with HIV: A Cross-Sectional Study from Southeastern Brazil
Rodrigues¹ JO, Silva TL, de Souza LdR.. Research Square, 2026-10-06
Topic: Brain imaging, connectivity and assessment
Mean age was 59.6 years, and 57.8% were male. Frailty status, including 8.6% frail and 52.3% pre-frail, was associated with lower BMI (p = 0.035). Positive neurocognitive screening (57.8%) was associated with lower education, polypharmacy, and falls (32.4% vs. 13.0%; p = 0.011). Frailty and cognitive impairment are prevalent among aging PLWH; falls were significantly associated with positive neurocognitive screening.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Rodrigues¹, J. O., Silva, T. L., & LdR, d. S. (2026). Brief Communication: Frailty and Neurocognitive Impairment in Older People Living with HIV: A Cross-Sectional Study from Southeastern Brazil. Research Square. https://doi.org/10.21203/rs.3.rs-11107308/v1
Vancouver
Rodrigues¹ JO, Silva TL, LdR dS. Brief Communication: Frailty and Neurocognitive Impairment in Older People Living with HIV: A Cross-Sectional Study from Southeastern Brazil. Research Square. 2026. doi:10.21203/rs.3.rs-11107308/v1.
BibTeX
@article{rodrigues2026-7cb394ba,
author = {Rodrigues¹, J. O. and Silva, T. L. and LdR, de Souza},
title = {{Brief Communication: Frailty and Neurocognitive Impairment in Older People Living with HIV: A Cross-Sectional Study from Southeastern Brazil}},
journal = {Research Square},
year = {2026},
doi = {10.21203/rs.3.rs-11107308/v1},
url = {https://doi.org/10.21203/rs.3.rs-11107308/v1}
}
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Key findings
- Mean age was 59.6 years, and 57.8% were male.
- Frailty status, including 8.6% frail and 52.3% pre-frail, was associated with lower BMI (p = 0.035).
- Positive neurocognitive screening (57.8%) was associated with lower education, polypharmacy, and falls (32.4% vs. 13.0%; p = 0.011).
- Frailty and cognitive impairment are prevalent among aging PLWH; falls were significantly associated with positive neurocognitive screening.
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Study details
- Study designcross-sectional
- Effect size57.8%; 8.6%; 52.3%
- Evidence strengthLow
How this study scored 16/100
Preprint — not yet peer-reviewed. It scored 31 on the same rubric, but non-peer-reviewed sources are capped at 16, so it shows as 16. Scored zero for sample size, studied in people and randomised / blinded because the record does not state it. We have no data on times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record and multi-centre collaboration, so those were left out: it earned 19 of the 62 points we could judge it on, which is 31 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 2 / 10 | Tier 4 — not a peer-reviewed journal (Research Square) |
| Journal's citation record | 0 / 4 | Not a journal article, so the journal's record does not count |
| Study design | 4 / 12 | A snapshot of people at one point in time |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 4 / 10 | Preprint — not yet peer-reviewed. Hosted on a preprint server. |
| How recent | 5 / 5 | 2026 — within 1 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 1 / 2 | Not in PubMed, but has a DOI |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Points | 19 / 62 | Scored on 12 of 20 parts. We have no data for the rest, so they are left out: 19 of the 62 points we could judge it on is 31 out of 100. |
| Total | 31 / 100 | Capped to 16 because this is not a peer-reviewed article. |
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