- 1,094studies on this subject, of 27,380 in the library
- 1,044peer-reviewed
- 1963–2026years published
- 46median usefulness score out of 100
These counts and lists are worked out from the library itself each time the page loads. A score rates how much weight a study can bear — its design, journal, evidence and recency — not whether its result is good news. How we score a study. For a plain-English guide to this subject, see Digital health.
The 20 highest-scoring studies
- Effectiveness of Implementing a Collaborative Chronic Care Model for Clinician Teams on Patient Outcomes and Health Status in Mental Health: A Randomized Clinical Trial
- Effects of Resistance Exercise Training on Cognitive Function and Physical Performance in Cognitive Frailty: A Randomized Controlled Trial
- Representation of patients with dementia in clinical trials of donepezil
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A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease
Using cerebrospinal fluid proteomics in 3,397 individuals, the ratio YWHAG:NPTX2 explained variance in cognitive impairment beyond amyloid-beta and tau measures and predicted conversion from cognitively normal to mild cognitive impairment and from mild cognitive impairment to dementia. It is described as a prognostic biomarker, not a treatment, cure, or prevention.
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A multilayer multimodal detection and prediction model based on explainable artificial intelligence for Alzheimer's disease
The text only notes that physicians struggle to interpret these models and find it hard to trust them. No information is given about whether the model improves diagnosis, treatment, or prevention of Alzheimer's disease.
- Statin therapy and risk of Alzheimer's and age-related neurodegenerative diseases
- Patients with chronic kidney disease are at an elevated risk of dementia: a population-based cohort study in Taiwan
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Cognitive stimulation to improve cognitive functioning in people with dementia
Cognitive stimulation showed moderate-quality evidence for a small benefit in cognition and slight improvements in quality of life, communication, and social interaction in people with dementia. This is a non-drug intervention that may help with symptoms but does not cure or prevent Alzheimer's disease.
- Balance and strength training in older adults: intervention gains and Tai Chi maintenance
- Deep Learning in Alzheimer's Disease: Diagnostic Classification and Prognostic Prediction Using Neuroimaging Data
- Interpreting artificial intelligence models: a systematic review on the application of LIME and SHAP in Alzheimer's disease detection
- Hearing Impairment Affects Dementia Incidence. An Analysis Based on Longitudinal Health Claims Data in Germany
- Do We Need to Rethink the Epidemiology and Healthcare Utilization of Parkinson's Disease in Germany?
- Gait variability in people with neurological disorders: A systematic review and meta-analysis
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AI-based differential diagnosis of dementia etiologies on multimodal data
An AI model using demographics, medical history, neuropsychological assessments, and multimodal neuroimaging across 51,269 participants identified 10 dementia etiologies, with a microaveraged AUROC of 0.96 for differentiating etiologies. This is a diagnostic tool, not a treatment, cure, or prevention for Alzheimer's disease.
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Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: A systematic review
This review of 255 studies on AI and brain imaging for dementia found that most (71%) relied on a single research dataset (ADNI) and that few tested their models on an independent group of patients. Discriminative models performed best at telling Alzheimer's disease apart from healthy controls, but accuracy varied with the patients, scan types and methods used. The authors call for clearer reporting and independent validation before these tools reach practice. The review concerns diagnosis and prognosis only, not treatment or prevention.
- Diagnostic power of resting-state fMRI for detection of network connectivity in Alzheimer's disease and mild cognitive impairment: A systematic review
- Machine Learning and Novel Biomarkers for the Diagnosis of Alzheimer's Disease
- Drugs Contributing to Anticholinergic Burden and Risk of Fall or Fall-Related Injury among Older Adults with Mild Cognitive Impairment, Dementia and Multiple Chronic Conditions: A Retrospective Cohort Study
- Risks of Major Long-Term Side Effects Associated with Androgen-Deprivation Therapy in Men with Prostate Cancer
See all 1,094 studies in Digital health tools, with filters →
Newest additions on this subject
- Speaker-Wise Dementia Screening fromNaturalistic Speech with Lexical Entropy, Semantic Drift, and Multimodal Fusion
- Integrating Multisource Target Evidence with Machine-Learning Potency Prediction for Alzheimer’s Disease Drug Discovery
- Understanding Performance Plateaus and Representation Collapse in 3D MRI Transformers Trained to Classify Brain Disease
- Individual Angiotensin Receptor Blockers and Risk of Dementia: A Target Trial Emulation Study
- PaliGemX: An Interpretable Multimodal Transformer for Early Alzheimer’s Detection
- Speaker-Attributed Transcription Toward Automated Scoring of NACC Uniform Data Set Assessments: A Whisper–Pyannote Pipeline and Pilot Evaluation
- Surrogate variables and the risk of overfitting in neuropsychiatric gene expression analyses
- Electronic Health Record-Based Machine Learning Models for Predicting Revascularization, Amputation, and Cardiovascular Mortality in At-Risk Patients
- EEG Pathology Detection via Clinical Concept Bottleneck Models
- Identifying Individualized Multiple Chronic Condition Pathways Associated with Dementia
All 1,094 studies in Digital health tools, newest first →
What the library holds on this subject
By review status
| Status | Studies |
|---|---|
| Peer-reviewed | 1,044 |
| Preprint — not yet peer-reviewed | 49 |
| Retracted — do not rely on it | 1 |
By strength of evidence
| Rated in our summary | Studies |
|---|---|
| low | 769 |
| moderate | 248 |
| high | 77 |
Most frequent journals
| Journal | Studies |
|---|---|
| Neurology | 37 |
| Brain : a journal of neurology | 30 |
| Alzheimer's & dementia : the journal of the Alzheimer's Association | 27 |
| Journal of the American Geriatrics Society | 24 |
| Journal of Alzheimer's disease : JAD | 19 |
| NeuroImage | 19 |
| medRxiv | 17 |
| Alzheimer's research & therapy | 15 |
| Annals of neurology | 15 |
| Frontiers in aging neuroscience | 15 |
Studies by year published
| Year | Studies | Bar |
|---|---|---|
| 2026 | 75 | |
| 2025 | 146 | |
| 2024 | 21 | |
| 2023 | 27 | |
| 2022 | 59 | |
| 2021 | 76 | |
| 2020 | 81 | |
| 2019 | 80 | |
| 2018 | 61 | |
| 2017 | 47 | |
| 2016 | 43 | |
| 2015 | 37 | |
| 2014 | 37 | |
| 2013 | 25 | |
| 2012 | 25 | |
| 2011 | 21 | |
| 2010 | 23 | |
| 2009 | 21 | |
| 2008 | 17 | |
| 2007 | 21 | |
| 2006 | 9 | |
| 2005 | 11 | |
| 2004 | 11 | |
| 2003 | 15 | |
| 2002 | 8 | |
| 2001 | 7 | |
| 2000 | 13 | |
| 1999 | 5 | |
| 1998 | 6 | |
| 1997 | 8 | |
| 1996 | 10 | |
| 1995 | 3 | |
| 1994 | 4 | |
| 1993 | 4 | |
| 1992 | 5 | |
| 1991 | 3 | |
| 1990 | 5 | |
| 1989 | 1 | |
| 1988 | 6 | |
| 1987 | 3 | |
| 1986 | 2 | |
| 1985 | 5 | |
| 1984 | 1 | |
| 1982 | 1 | |
| 1978 | 2 | |
| 1977 | 1 | |
| 1974 | 1 | |
| 1963 | 1 |
Counts the 1,094 studies with a usable publication date. The library is a large sample of published work, not a complete index, so these counts describe the library, not the whole field.
Other subjects in the library
- Getting a diagnosis
- Biomarkers
- Clinical trials
- Prevention and risk
- Caregiving
- How common it is
- Costs and economics
- Genetics
- Laboratory science
- Disease mechanisms
- Vascular contributions
- Prevention trials
- Clinical safety
- Health systems and care delivery
- End-of-life care
- Risk factors
- Treatments
- Disparities
- Mild cognitive impairment
- Risk genes beyond APOE
- Brain scans and imaging
- TREM2 and immune genetics
- Cognitive tests and assessment
- Lewy body dementia
- Down syndrome and Alzheimer's
- Long-term cohort studies
- Inflammation and the immune system
- Tau biomarkers
- Brain tissue and pathology
- Drug development
- Hippocampus size on brain scans