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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,301–23,325 of 27,380 studies, newest first · page 933 of 1096.

January 2006 25

  1. 2006-01-10

    Fornix integrity and hippocampal volume in male schizophrenic patients

    ✓ Peer-reviewed Hippocampus size on brain scans Biological psychiatry

    Key finding: These findings demonstrate a disruption in fornix integrity in patients with schizophrenia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2006-01-09

    Subjective complaints precede Parkinson disease: the rotterdam study

    ✓ Peer-reviewed Long-term cohort studies Archives of neurology

    Key finding: Neuronal degeneration and dopamine loss in the preclinical phase of Parkinson disease may produce subtle complaints before clinically recognizable symptoms emerge. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2006-01-09

    The neuropeptide PACAP promotes the alpha-secretase pathway for processing the Alzheimer amyloid precursor protein

    ✓ Peer-reviewed Risk genes beyond APOE FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Key finding: Its specific G protein-coupled receptor PAC1 is expressed in several central nervous system (CNS) regions, including the hippocampal formation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2006-01-09

    What best differentiates Lewy body from Alzheimer's disease in early-stage dementia?

    ✓ Peer-reviewed Disparities Brain : a journal of neurology

    Key finding: There were no group differences with regard to age, gender, education or global severity of dementia at presentation (mean Mini-Mental State Examination: 24.0 versus 25.0, mean Dementia Rating Scale: 123.6 versus 125.7). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2006-01-05

    The lifetime risk of stroke: estimates from the Framingham Study

    ✓ Peer-reviewed How common it is Stroke

    Key finding: The LTR of stroke in middle-aged adults is 1 in 6 or more, which is equal to or greater than the LTR of AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2006-01-04

    Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment Neuroscience letters

    Key finding: In the present study we show for the first time in brain obtained at short postmortem intervals that the levels of HNE are elevated in mild cognitive impairment (MCI) hippocampus and inferior parietal lobules compared to those of control brain. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2006-01-04

    Differential regional atrophy of the cingulate gyrus in Alzheimer disease: a volumetric MRI study

    ✓ Peer-reviewed Brain scans and imaging Cerebral cortex (New York, N.Y. : 1991)

    Key finding: Cingulate cortical volumes of 10 familial AD patients were compared with 10 age- and sex-matched controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2006-01-01

    The clinical and cost-effectiveness of donepezil, rivastigmine, galantamine and memantine for Alzheimer's disease

    ⚠ Report — not peer-reviewed Costs and economics Health Technology Assessment

    Key finding: For mild to moderately severe AD, the results of the study suggested that all three treatments were beneficial when assessed using cognitive outcome measures. +4 more findings

    Scored 44 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  9. 2006 year only

    Cognitive reserve and Alzheimer disease

    ✓ Peer-reviewed Risk factors Alzheimer disease and associated disorders

    Key finding: Epidemiologic evidence suggests that individuals with higher IQ, education, occupational attainment, or participation in leisure activities have a reduced risk of developing Alzheimer disease (AD).

    Full summary, score breakdown and related studies → Original source

  10. 2006 year only

    Acetylcholinesterase inhibitors and sleep architecture in patients with Alzheimer's disease

    ✓ Peer-reviewed Treatments Drugs & aging

    Key finding: AChEI therapy had a significant effect on the percentage of stage 1 (p = 0.01) and stage 2 (p = 0.03) sleep. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2006-01-01

    Substantia nigra tangles are related to gait impairment in older persons

    ✓ Peer-reviewed Digital health tools Annals of neurology

    Key finding: NFTs in the substantia nigra are associated with gait impairment in older persons with and without dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2006-01-01

    Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

    ✓ Peer-reviewed Clinical safety Biochemistry

    Key finding: We describe solid-state nuclear magnetic resonance (NMR) measurements on fibrils formed by the 40-residue beta-amyloid peptide associated with Alzheimer's disease (Abeta(1-40)) that place constraints on the identity and symmetry of contacts between in-register, parallel beta-sheets in the fibrils.

    Full summary, score breakdown and related studies → Original source

  13. 2006-01-01

    A life-course approach to the aetiology of late-onset dementias

    ✓ Peer-reviewed Disparities The Lancet. Neurology

    Key finding: Genetic and environmental factors probably interact to determine vulnerability to the dementias. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2006-01-01

    The role of inflammation in CNS injury and disease

    ✓ Peer-reviewed Inflammation and the immune system British journal of pharmacology

    Key finding: Chronic disorders represent a greater therapeutic challenge, a problem highlighted in Alzheimer's disease (AD); significant data suggested that anti-inflammatory agents might reduce the probability of developing AD, or slow its progression, but prospective clinical trials of nonsteroidal anti-inflammatory drugs or cyclooxygenase inhibitors have been disappointing.

    Full summary, score breakdown and related studies → Original source

  15. 2006-01-01

    Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism

    ✓ Peer-reviewed Risk factors Chemical biology & drug design

    Key finding: Several small polyphenol molecules have been demonstrated to remarkably inhibit the formation of fibrillar assemblies in vitro and their associated cytotoxicity.

    Full summary, score breakdown and related studies → Original source

  16. 2006-01-01

    Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease

    ✓ Peer-reviewed Risk factors Journal of applied physiology (Bethesda, Md. : 1985)

    Key finding: These findings, collectively, highlight the importance of neurovascular coupling to the health of the normal brain and suggest a therapeutic target for improving brain function in pathologies associated with cerebrovascular dysfunction.

    Full summary, score breakdown and related studies → Original source

  17. 2006-01-01

    Memantine: a review of its use in Alzheimer's disease

    ✓ Peer-reviewed Treatments Drugs

    Key finding: Memantine is approved in the US and the EU for the treatment of patients with moderate to severe dementia of the Alzheimer's type. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2006-01-01

    Role of melatonin in Alzheimer-like neurodegeneration

    ✓ Peer-reviewed Treatments Acta pharmacologica Sinica

    Key finding: Recent studies showed that melatonin, an indoleamine secreted by the pineal gland, may play an important role in aging and AD as an antioxidant and neuroprotector. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2006-01-01

    Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain

    ✓ Peer-reviewed Treatments Nature protocols

    Key finding: It is becoming increasingly important to separately quantify various components of the Alzheimer's pathology, given the advancement of amyloid-lowering therapies into clinical trials. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2006-01-01

    Patterns of brain atrophy that differentiate corticobasal degeneration syndrome from progressive supranuclear palsy

    ✓ Peer-reviewed Brain scans and imaging Archives of neurology

    Key finding: Distinct patterns of brain atrophy exist in CBDS and PSP that can be used to differentiate the 2 diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2006-01-01

    Computerized cognitive testing battery identifies mild cognitive impairment and mild dementia even in the presence of depressive symptoms

    ✓ Peer-reviewed Cognitive tests and assessment American journal of Alzheimer's disease and other dementias

    Key finding: Cognitive and depressive symptoms co-occur, complicating detection of mild cognitive impairment (MCI) and early dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2006-01-01

    Cost-of-illness studies : a review of current methods

    ✓ Peer-reviewed Vascular contributions PharmacoEconomics

    Key finding: There was also evidence to suggest that the strengths and weaknesses of each method were considered when applying a method to a specific illness.

    Full summary, score breakdown and related studies → Original source

  23. 2006-01-01

    Traumatic stress: effects on the brain

    ✓ Peer-reviewed Hippocampus size on brain scans Dialogues in clinical neuroscience

    Key finding: Traumatic stress can be associated with lasting changes in these brain areas. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2006-01-01

    Protective and damaging effects of stress mediators: central role of the brain

    ✓ Peer-reviewed Hippocampus size on brain scans Dialogues in clinical neuroscience

    Key finding: It is notjust the dramatic stressful events that exact their toll, but rather the many events of daily life that elevate and sustain activities of physiological systems and cause sleep deprivation, overeating, and other health-damaging behaviors, producing the feeling of being "stressed out." +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2006-01-01

    Family decision-making for nursing home residents with dementia: rural-urban differences

    ✓ Peer-reviewed End-of-life care The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association

    Key finding: Most rural focus group participants voiced unqualified acceptance of death and placed few conditions on death, beyond their hope that it would be quick and peaceful. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →