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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 22,926–22,950 of 27,380 studies, newest first · page 918 of 1096.

October 2006 25

  1. 2006-10-13

    The significance of the cholinergic system in the brain during aging and in Alzheimer's disease

    ✓ Peer-reviewed Risk factors Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: Acetylcholine is widely distributed in the nervous system and has been implicated to play a critical role in cerebral cortical development, cortical activity, controlling cerebral blood flow and sleep-wake cycle as well as in modulating cognitive performances and learning and memory processes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2006-10-13

    Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat

    ✓ Peer-reviewed Hippocampus size on brain scans Neuroscience

    Key finding: Initial mapping revealed that chronic imipramine treatment increased expression of these plasticity-associated proteins in the hippocampus, medial prefrontal cortex and piriform cortex but not in the other brain regions examined. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2006-10-12

    Assessing the cognitive impact of Alzheimer disease pathology and vascular burden in the aging brain: the Geneva experience

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica

    Key finding: Recent neuropathologic studies strongly suggested that the clinical diagnosis of dementia depends more on the severity and topography of pathological changes than on the presence of a qualitative marker. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2006-10-10

    Mediterranean Diet, Alzheimer Disease, and Vascular Mediation

    ✓ Peer-reviewed Risk factors Archives of Neurology

    Key finding: Higher adherence to the MeDi was associated with lower risk for AD (odds ratio, 0.76; 95% confidence interval, 0.67-0.87; P<.001). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2006-10-10

    Decision rules guiding the clinical diagnosis of Alzheimer's disease in two community-based cohort studies compared to standard practice in a clinic-based cohort study

    ✓ Peer-reviewed Long-term cohort studies Neuroepidemiology

    Key finding: Of 306 clinic cases with probable AD, 286 (93.5%) met CERAD neuropathologic criteria for AD; the results were comparable for those with possible AD (51 of 54, 94.4%). +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2006-10-05

    Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease

    ✓ Peer-reviewed Brain tissue and pathology Neurobiology of disease

    Key finding: We have characterized the natural history of beta-amyloid deposition in APPswe/PS1dE9 mice, a particularly aggressive transgenic mouse model generated with mutant transgenes for APP (APPswe: KM594/5NL) and PS1 (dE9: deletion of exon 9). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2006-10-04

    Hippocampal volume reduction and HPA-system activity in major depression

    ✓ Peer-reviewed Hippocampus size on brain scans Journal of psychiatric research

    Key finding: Structural imaging studies investigating hippocampal volumes in patients suffering from major depression have yielded mixed results. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2006-10-04

    Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

    ✓ Peer-reviewed Laboratory science Journal of Neuroscience

    Key finding: In addition, levels of the activation subunit of cyclin-dependent kinase 5, p25, are elevated significantly at 9 months in 5XFAD brain, although an upward trend is observed by 3 months of age, before significant neurodegeneration or neuron loss.

    Full summary, score breakdown and related studies → Original source

  9. 2006-10-04

    Metallothionein-I and -III expression in animal models of Alzheimer disease

    ✓ Peer-reviewed Biomarkers Neuroscience

    Key finding: These models express human beta-amyloid precursor protein (AbetaPP) carrying different mutations that subsequently result in a varied pattern of beta-amyloid (Abeta) deposition within the brain. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2006-10-03

    3D comparison of hippocampal atrophy in amnestic mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Brain : a journal of neurology

    Key finding: Age, race, gender, education and Mini-Mental State Examination were significant predictors of hippocampal volume. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2006-10-02

    Reliability and validity of a computerized neurocognitive test battery, CNS Vital Signs

    ✓ Peer-reviewed Risk factors Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

    Key finding: Test-retest reliability (TRT) was evaluated in 99 Ss who took the battery on two separate occasions, separated, on the average, by 62 days; the results were comparable to those achieved by equivalent conventional and computerized tests.

    Full summary, score breakdown and related studies → Original source

  12. 2006-10-02

    The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia

    ✓ Peer-reviewed Inflammation and the immune system Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Structural modeling suggests that the enhanced ability of Envs with N283 to use low levels of CD4 is due to a hydrogen bond formed with Gln 40 of CD4. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2006-10 month only

    Randomized controlled trial of standardized Bacopa monniera extract in age-associated memory impairment

    ✓ Peer-reviewed Clinical trials Indian journal of psychiatry

    Key finding: SBME produced significant improvement on mental control, logical memory and paired associated learning during the 12-week drug therapy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2006-10-01

    Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis

    ✓ Peer-reviewed Mild cognitive impairment The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Independent component analyses revealed specific memory-related networks that activated or deactivated during an associative memory paradigm. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2006-10-01

    Outcomes of antipsychotic drug use in community-dwelling elders with dementia

    ✓ Peer-reviewed Digital health tools Archives of psychiatric nursing

    Key finding: Overall, 27% of the sample was dispensed antipsychotic drugs, with the most prevalent type being atypical antipsychotic drugs.

    Full summary, score breakdown and related studies → Original source

  16. 2006-10-01

    The contribution of neuropsychiatric symptoms to the cost of dementia care

    ✓ Peer-reviewed Costs and economics International journal of geriatric psychiatry

    Key finding: BPSD contribute significantly to the overall costs of dementia care. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2006-10-01

    CNS immune privilege: hiding in plain sight

    ✓ Peer-reviewed Vascular contributions Immunological reviews

    Key finding: This newer view of CNS immune privilege is opening the door for therapies designed to harness autoreactive lymphocyte responses and also implies (i) that CNS autoimmune diseases (i.e. multiple sclerosis) may result as much from neuronal and/or glial dysfunction as from immune system dysfunctions and (ii) that the severe neuronal and glial dysfunction associated with neurodegenerative disorders (i.e.

    Full summary, score breakdown and related studies → Original source

  18. 2006-10-01

    Sleep deprivation as a neurobiologic and physiologic stressor: Allostasis and allostatic load

    ✓ Peer-reviewed Risk factors Metabolism: clinical and experimental

    Key finding: Repeated stress in animal models causes brain regions involved in memory and emotions, such as hippocampus, amygdala, and prefrontal cortex, to undergo structural remodeling with the result that memory is impaired and anxiety and aggression are increased. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2006-10-01

    Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease

    ✓ Peer-reviewed Clinical trials The New England journal of medicine

    Key finding: Adverse effects offset advantages in the efficacy of atypical antipsychotic drugs for the treatment of psychosis, aggression, or agitation in patients with Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2006-10-01

    Sequential phosphorylation of tau protein by cAMP-dependent protein kinase and SAPK4/p38delta or JNK2 in the presence of heparin generates the AT100 epitope

    ✓ Peer-reviewed Drug development Journal of neurochemistry

    Key finding: Phosphorylation by PKA and SAPK4/p38delta abolished the ability of tau to promote microtubule assembly, but failed to influence significantly the heparin-induced assembly of tau into filaments.

    Full summary, score breakdown and related studies → Original source

  21. 2006-10-01

    Satisfaction with end-of-life care for nursing home residents with advanced dementia

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: Better communication, greater resident comfort, no tube feeding, and care in a specialized dementia unit are modifiable factors that may improve satisfaction with care in advanced dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2006-10-01

    REM sleep behavior disorder and REM sleep without atonia in probable Alzheimer disease

    ✓ Peer-reviewed Disease mechanisms Sleep

    Key finding: Study objective To determine the frequency of rapid eye movement (REM) sleep behavior disorder (RBD) and REM sleep without atonia among patients with Alzheimer disease and control subjects.

    Full summary, score breakdown and related studies → Original source

  23. 2006-10-01

    Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein

    ✓ Peer-reviewed Disease mechanisms Archives of neurology

    Key finding: These results provide a link between tau autoimmunity and tauopathy-like abnormalities and indicate potential dangers of using tau for immunotherapy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2006-10-01

    LRRK2 expression in normal and pathologic human brain and in human cell lines

    ✓ Peer-reviewed Inflammation and the immune system Journal of neuropathology and experimental neurology

    Key finding: It intensely labels Lewy bodies in Parkinson disease and related neurodegenerative disorders. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2006-10-01

    The Uniform Data Set (UDS): Clinical and Cognitive Variables and Descriptive Data From Alzheimer Disease Centers

    ✓ Peer-reviewed Long-term cohort studies Alzheimer Disease & Associated Disorders

    A Clinical Task Force, composed of clinical leaders from Alzheimer's Disease Centers (ADC), was convened by the National Institute on Aging to develop a uniform set of assessment procedures to characterize individuals with mild Alzheimer disease and mild cognitive impairment in comparison with nondemented aging.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →