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40/100

✓ Peer-reviewed alzhub usefulness score 40 out of 100. Down syndrome and Alzheimer's

Topic: Risk, prevention and care in population studies

We propose that sleep disruption is a lever arm that influences how cognition emerges in development and then declines in response to Alzheimer disease in people with Down syndrome. Addressing sleep disruptions might be an overlooked way to improve cognitive outcomes in this population. This article is a contribution to a Special Issue on Down Syndrome curated by the editors of the Journal of Alzheimer's Disease & Parkinsonism.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Fernandez, F., & Edgin, J. O. (2013). Poor Sleep as a Precursor to Cognitive Decline in Down Syndrome : A Hypothesis. Journal of Alzheimer's disease & Parkinsonism. https://doi.org/10.4172/2161-0460.1000124

Vancouver

Fernandez F, Edgin JO. Poor Sleep as a Precursor to Cognitive Decline in Down Syndrome : A Hypothesis. Journal of Alzheimer's disease & Parkinsonism. 2013. doi:10.4172/2161-0460.1000124. PMID: 24558640.

BibTeX

@article{fernandez2013-24558640,
  author  = {Fernandez, F. and Edgin, J. O.},
  title   = {{Poor Sleep as a Precursor to Cognitive Decline in Down Syndrome : A Hypothesis}},
  journal = {Journal of Alzheimer's disease \& Parkinsonism},
  year    = {2013},
  doi     = {10.4172/2161-0460.1000124},
  pmid    = {24558640},
  url     = {https://doi.org/10.4172/2161-0460.1000124}
}

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Key findings

We propose that sleep disruption is a lever arm that influences how cognition emerges in development and then declines in response to Alzheimer disease in people with Down syndrome.
Addressing sleep disruptions might be an overlooked way to improve cognitive outcomes in this population.
This article is a contribution to a Special Issue on Down Syndrome curated by the editors of the Journal of Alzheimer's Disease & Parkinsonism.

Why it matters

This article proposes that poor sleep may affect how cognition develops and declines in people with Down syndrome, and that addressing sleep problems might improve cognitive outcomes. It is a hypothesis paper, so the idea has not been tested as a treatment.

Study details

Evidence strengthLow

How this study scored 40/100

Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on journal's citation record and senior author's track record, so those were left out: it earned 37 of the 92 points we could judge it on, which is 40 out of 100.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Journal of Alzheimer's disease & Parkinsonism)
Journal's citation record	— / 4	No journal record from OpenAlex — left out of this score
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	1 / 5	2013 — within 20 year(s) of the newest study here
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	4 / 7	Cited 50 times (OpenAlex, 2026-10-10)
Citations per year	2 / 5	3.3 citations a year over 15 year(s) since 2013
Impact for its field and year	3 / 6	Cited 4.4× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	1 / 6	Cited by 1 other studies in this library
Still being cited	1 / 4	Cited 5 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	— / 4	Senior author's record not available — left out of this score
Institution's track record	2 / 3	Johns Hopkins University: institution h-index 2,306 (OpenAlex)
Multi-centre collaboration	1 / 3	OpenAlex lists 2 institution(s) in 1 country
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 24558640)
Free to read	2 / 2	Free to read
Points	37 / 92	Scored on 18 of 20 parts. We have no data for the rest, so they are left out: 37 of the 92 points we could judge it on is 40 out of 100.
Total	40 / 100	—

What each of these 20 components measures, and what this score is not →

Read the original

Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).

Studies this one cites

Referenced by this study and also in the alzhub library, so you can read them here.

Later studies that cite this one

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