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Depressive symptoms predict incident dementia during short- but not long-term follow-up period
Mirza SS, de Bruijn RF, Direk N, Hofman A, Koudstaal PJ, Ikram MA, Tiemeier H.. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2014-02-12
Topic: Risk, prevention and care in population studies
Background Whether depression is a long-term risk factor for dementia or represents a dementia prodrome is unclear. Therefore, we examined the relationship between depressive symptoms and dementia during short and long follow-up in a population-based cohort. Methods In the Rotterdam Study, 4393 nondemented individuals were followed for incident dementia for 13.7 years by continuous monitoring.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Mirza, S. S., de Bruijn, R. F., Direk, N., Hofman, A., Koudstaal, P. J., Ikram, M. A., et al. (2014). Depressive symptoms predict incident dementia during short- but not long-term follow-up period. Alzheimer's & dementia : the journal of the Alzheimer's Association. https://doi.org/10.1016/j.jalz.2013.10.006
Vancouver
Mirza SS, de Bruijn RF, Direk N, Hofman A, Koudstaal PJ, Ikram MA, et al. Depressive symptoms predict incident dementia during short- but not long-term follow-up period. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2014. doi:10.1016/j.jalz.2013.10.006. PMID: 24530024.
BibTeX
@article{mirza2014-24530024,
author = {Mirza, S. S. and de Bruijn, R. F. and Direk, N. and Hofman, A. and Koudstaal, P. J. and Ikram, M. A. and Tiemeier, H.},
title = {{Depressive symptoms predict incident dementia during short- but not long-term follow-up period}},
journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
year = {2014},
doi = {10.1016/j.jalz.2013.10.006},
pmid = {24530024},
url = {https://doi.org/10.1016/j.jalz.2013.10.006}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
Key findings
- Therefore, we examined the relationship between depressive symptoms and dementia during short and long follow-up in a population-based cohort.
- Methods In the Rotterdam Study, 4393 nondemented individuals were followed for incident dementia for 13.7 years by continuous monitoring.
- Cox proportional hazards models for different time intervals were used to estimate the risk of incident dementia.
- Results Five-hundred eighty-two participants developed dementia during 13.7 years.
Why it matters
In 4,393 nondemented Rotterdam Study participants followed for 13.7 years, depressive symptoms predicted incident dementia during short but not long follow-up. This suggests depression may sometimes be an early sign of dementia rather than a long-term cause, and it does not test any treatment, cure, or prevention.
Study details
- Effect sizeor 13.7
- Evidence strengthModerate
How this study scored 47/100
Published in a leading specialty journal. Scored zero for study design, sample size, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (Alzheimer's & dementia : the journal of the Alzheimer's Association) |
| Journal's citation record | 2 / 4 | Alzheimer s & Dementia: journal h-index 228 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2014 — within 20 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 4 / 7 | Cited 73 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 5.2 citations a year over 14 year(s) since 2014 |
| Impact for its field and year | 3 / 6 | Cited 3.4× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 6 other studies in this library |
| Still being cited | 2 / 4 | Cited 16 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Henning W. Tiemeier: h-index 144 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Erasmus MC: institution h-index 1,321 (OpenAlex) |
| Multi-centre collaboration | 0 / 3 | OpenAlex lists 1 institution(s) in 1 country — scores zero (affiliation lists can be incomplete) |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 24530024) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 47 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/j.jalz.2013.10.006
- PubMed: 24530024
- Original source →
- Free full text: Alzheimer s & Dementia →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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