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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 2,676–2,700 of 27,380 studies, newest first · page 108 of 1096.

November 2025 25

  1. 2025-11-13

    Higher neighborhood deprivation is associated with accelerated disease progression in behavioral‐variant frontotemporal degeneration

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia Behavior & Socioeconomics of Aging

    Key finding: Living in more deprived neighborhoods was associated with an accelerated disease course in bvFTD, highlighting an important socioeconomic disparity in disease prognosis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2025-11-13

    Depressive symptoms and plasma AT(N) biomarkers among cognitively healthy and mild cognitively impaired in a diverse cohort

    ✓ Peer-reviewed Tau biomarkers Neurobiology of aging

    Key finding: We cross-sectionally studied 2929 dementia-free participants from the Health & Aging Brain Study-Health Disparities (HABS-HD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2025-11-12

    Single-nucleus multi-omics identifies shared and distinct pathways in Pick's and Alzheimer's disease

    ✓ Peer-reviewed Genetics Science advances

    Key finding: Notably, we identified a distal human-gained enhancer (HGE) associated with E3 ubiquitin ligase (UBE3A), highlighting disease-specific regulatory alterations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2025-11-12

    APOE-Targeted Therapeutics for Alzheimer's Disease

    ✓ Peer-reviewed Genetics The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: These changes disrupt lipid homeostasis, increase risk of chronic unresolved neuroinflammation and vascular inflammation, and cause breakdown of the blood-brain barrier (BBB), thus increasing neuronal vulnerability to disease pathology and elevating risk for Alzheimer's disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2025-11-12

    Increased iron deposition in putamen and substantia nigra correlates with cognitive function in cerebral small vessel disease: A quantitative susceptibility mapping study

    ✓ Peer-reviewed Vascular contributions Journal of Cerebral Blood Flow & Metabolism

    Key finding: CSVD patients exhibited increased susceptibility values in bilateral caudate nucleus, putamen, pallidus, thalamus, substantia nigra (SN), and left red nucleus, and decreased susceptibility values in left amygdala, compared to HC. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2025-11-12

    Income, Race-Ethnicity, and Dementia Risk Factors in the United States

    ✓ Peer-reviewed Risk factors Neurology

    Key finding: There were 13,145 individuals with risk factor data between 2015 and 2018 (51.1% aged 18-44, 31.0% aged 45-64, and 17.9% aged ≥65 years; 51.5% female after survey-weighting). +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2025-11-12

    A deep dive into statistical modeling of RNA splicing QTLs reveals variants that explain neurodegenerative disease

    ✓ Peer-reviewed Genetics The American Journal of Human Genetics

    Key finding: By applying MAJIQTL to GTEx, we find significantly more sGenes harboring sQTLs with functional significance.

    Full summary, score breakdown and related studies → Original source

  8. 2025-11-11

    APOE4 to APOE2 allelic switching in mice improves Alzheimer's disease-related metabolic signatures, neuropathology and cognition

    ✓ Peer-reviewed Genetics Nature neuroscience

    Key finding: Compared to individuals carrying two copies of the ε4 allele of apolipoprotein E (APOE), ε2 homozygotes have an approximate 99% reduction in late-onset Alzheimer's disease (AD) risk. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2025-11-11

    Can a Mediterranean diet prevent cognitive decline?

    ✓ Peer-reviewed Prevention trials Zenodo (CERN European Organization for Nuclear Research)

    Key finding: Current evidence suggests a potential for the Mediterranean diet to prevent cognitive decline, largely supported by observational studies, although randomized controlled trials show mixed results.

    Full summary, score breakdown and related studies → Original source

  10. 2025-11-11

    Can a Mediterranean diet prevent cognitive decline?

    ✓ Peer-reviewed Prevention trials Zenodo (CERN European Organization for Nuclear Research)

    Key finding: Current evidence suggests a potential for the Mediterranean diet to prevent cognitive decline, largely supported by observational studies, although randomized controlled trials show mixed results.

    Full summary, score breakdown and related studies → Original source

  11. 2025-11-11

    Factors associated with anxiety, stress, depression and burden among informal caregivers of patients with dementia: a cross-sectional study

    ✓ Peer-reviewed Caregiving BMC Nursing

    Key finding: They exhibited normal intensity of depression, anxiety, and stress symptomatology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2025-11-10

    Utility of a contemporary digital cognitive-motor biomarker in Huntington's and Parkinson's diseases

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: BackgroundCognitive impairment significantly impacts the quality of life in patients with neurodegenerative disorders, including Huntington's disease (HD), Parkinson's disease (PD), and Alzheimer's disease (AD).ObjectiveThis study aims to assess the utility of MemTrax, a contemporary digital continuous recognition task platform originally developed for AD, as an effective tool for revealing cognitive and clinical motor impairments in HD and PD populations as aligned with respective disease staging. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2025-11-10

    Cost-consequence analysis of the partner in balance program for informal carers of persons with dementia

    ✓ Peer-reviewed Health systems and care delivery Aging & mental health

    Key finding: This study aims to evaluate the cost-consequence of PiB compared to usual care. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2025-11-10

    Needs of key stakeholders to make advance care plans and advance directives for people with dementia: a scoping review

    ✓ Peer-reviewed End-of-life care Zurich Open Repository and Archive (University of Zurich)

    Key finding: Key stakeholders included healthcare professionals (HCPs); family members and caregivers; PWD; dyads (PWD and their caregivers); the broader public; policymakers; and researchers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2025-11-10

    Needs of key stakeholders to make advance care plans and advance directives for people with dementia: a scoping review

    ✓ Peer-reviewed End-of-life care BMC Geriatrics

    Key finding: Key stakeholders included healthcare professionals (HCPs); family members and caregivers; PWD; dyads (PWD and their caregivers); the broader public; policymakers; and researchers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2025-11-10

    Detecting Transthyretin Cardiac Amyloidosis With Artificial Intelligence

    ✓ Peer-reviewed Digital health tools JAMA Cardiology

    Key finding: ATTRACTnet was developed in an internal test set of 799 patients (mean [SD] age, 75.1 [11.1] years; 516 [64.7%] male and 283 [35.3%] female) using 5-fold cross-validation with an additional external test set of 422 patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2025-11-10

    Acceptance Factors and Barriers to the Implementation of Digital Interventions in Older People with Dementia and/or Their Caregivers: An Umbrella Review

    ✓ Peer-reviewed Caregiving Journal of Clinical Medicine

    Key finding: Frequently reported factors included self-management support, information access, and enhanced communication, although these were not consistently addressed across all reviews. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2025-11-10

    Refining the diagnostic accuracy of Parkinsonian disorders using metaphenomic annotation of the clinicopathological literature

    ✓ Peer-reviewed Getting a diagnosis npj Parkinson s Disease

    Key finding: We found diagnostic accuracy was highest for multiple system atrophy (MSA, 92.8%) and lowest for dementia with Lewy bodies (DLB, 82.1%). +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2025-11-10

    Evaluation of a panel of plasma biomarkers for Alzheimer's disease in a diverse research cohort

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer s Disease

    Key finding: Plasma biomarkers demonstrate promise for improving diagnostic accuracy in diverse research cohorts. +2 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2025-11-10

    Plasma p-tau217 as a biomarker of Alzheimer's disease pathology in individuals with Down syndrome

    ✓ Peer-reviewed Biomarkers Nature communications

    Key finding: These findings support its use as a reliable, noninvasive tool for early AD detection and management in individuals with DS.

    Full summary, score breakdown and related studies → Original source

  21. 2025-11-10

    A Randomized Controlled Trial of the Safety and Efficacy of Dronabinol for Agitation in Alzheimer's Disease

    ✓ Peer-reviewed Clinical trials The American Journal of Geriatric Psychiatry

    Key finding: The majority of participants were female and were taking concomitant psychotropic medications (antidepressants and antipsychotics) at baseline. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2025-11-09

    Plasma NfL and GFAP in the preclinical stages of neurodegenerative diseases: insights from the UK Biobank

    ✓ Peer-reviewed Long-term cohort studies Journal of Neurology

    Key finding: The final sample included 1196 cases (505 PD, 26 APD, 476 AD, 189 ALS) and 44,107 control subjects. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2025-11-08

    Co-infection with two α-synuclein strains reveals novel synergistic interactions

    ✓ Peer-reviewed Brain tissue and pathology Acta neuropathologica

    Key finding: Unexpectedly, we found that PFFs generated using the same method differed in their ability to neuroinvade following sc.n. inoculation based on α-synuclein monomer source. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2025-11-08

    PolyGR-containing aggregates link with pathology and clinical features of Alzheimer's disease

    ✓ Peer-reviewed Brain tissue and pathology Acta neuropathologica

    Key finding: Here, we performed a comprehensive analysis to study if polyGR+ aggregates are associated with AD neuropathological changes (ADNC) and clinical features of AD cases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2025-11-08

    Role of TREM2 in neuroinflammation

    ✓ Peer-reviewed TREM2 and immune genetics Experimental neurology

    Key finding: A deeper understanding of TREM2-mediated signaling may uncover novel therapeutic targets and pathways with significant translational potential for treatment of CNS diseases.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →