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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 9,551–9,575 of 27,380 studies, newest first · page 383 of 1096.

December 2021 23

  1. 2021-12-01

    Depression and Functional Mobility Decline in Long Term Care Home Residents with Dementia: a Prospective Cohort Study

    ✓ Peer-reviewed Health systems and care delivery Canadian geriatrics journal : CGJ

    Key finding: Residents experienced a statistically significant decline in functional mobility in as soon as 60 days. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-12-01

    Dysfunction of the Blood-brain Barrier in Cerebral Microbleeds: from Bedside to Bench

    ✓ Peer-reviewed Vascular contributions Aging and disease

    Key finding: An increasing number of studies have demonstrated the significance of CMBs in stroke, dementia, Parkinson's disease, gait disturbances and late-life depression.

    Full summary, score breakdown and related studies → Original source

  3. 2021-12 month only

    Role of neurotoxicants in the pathogenesis of Alzheimer's disease: a mechanistic insight

    ✓ Peer-reviewed Risk genes beyond APOE Annals of medicine

    Key finding: Alzheimer's disease (AD) is the most conspicuous chronic neurodegenerative syndrome, which has become a significant challenge for the global healthcare system. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2021-12 month only

    Smartphone ownership and usage in Chinese- and English-speaking older adults

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: 33 Chinese- and 117 English-speaking older adults who received a diagnosis of normal cognition or mild cognitive impairment at consensus were included in the data analysis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-12-01

    Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages

    ✓ Peer-reviewed Brain scans and imaging Brain : a journal of neurology

    Key finding: We found that the cognitively unimpaired amyloid-β-negative individuals had significant longitudinal tau accumulation confined to the PET Braak-like stage I (3.9%) and II (2.8%) areas. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-12-01

    Geographic proximity, neuropathology and ADRC brain donation

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: Reducing Alzheimer disparities and generating the evidence needed to promote brain health for everyone requires diverse research representation, including areas near an ADRC. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-12-01

    Area‐level deprivation is associated with rate of memory decline in late life within a community‐based cohort

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: Even after accounting for established individual‐level demographic, socioeconomic, health, and genetic risk factors for cognitive decline, greater neighborhood disadvantage is associated with an accelerated rate of annualized decline in delayed recall performance across mid to late life in a community sample. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-12-01

    Spatiotemporal trends in dementia‐associated deaths, what do the data reveal?

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: There are factors, other than the step changes in underlying cause of death coding, driving the progressively increasing temporal trend in relative risk of dementia‐associated death. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2021-12-01

    Dementia care in diverse older adults in the Deep South and the rest of the United States

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: ADRD specialist and drug utilization is relatively low in both DS and non‐DS, with no significant R/E differences. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-12-01

    Frailty and Dementia: Differences in Health Care Utilization and Costs

    ✓ Peer-reviewed Risk factors Innovation in Aging

    Key finding: Frailty and dementia are associated with poor health outcomes and increased health care utilization. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-12-01

    Factors influencing medication adherence among U.S. Medicare beneficiaries with Alzheimer’s disease and related dementia (ADRD)

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: Adherence to ADRD medications was not associated with specialist availability but was related to individual and socioeconomic context factors in community‐dwelling older individuals with ADRD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-12-01

    The impact of built and social environmental characteristics on incidence and estimated risk of dementia

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: Associations of neighbourhood NO2 level, walkability, public open space and social fragmentation with dementia incidence and estimated future risk of dementia were statistically significant, indicating the potential to reduce the risk through changes in built and social environments. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-12-01

    Association of neighborhood socioeconomic disadvantage and cognitive decline

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: Neighborhood characteristics may play an influential role in SCD regardless of race/ethnicity and thus are likely important risk factors for AD/ADRD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2021-12-01

    Cross‐sectional association between the area deprivation index (ADI) and cognitive impairment in community‐dwelling older veterans

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: Participants were 1060 Veterans (response rate of 20.14%), mean age of 68.39 (SD=8.52) years, 59.0% Caucasian, 69.2% non‐Hispanic, 95.8% male, 12.0% screened positive for MCI and 15.6% for dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-12-01

    Dementia diagnosis patterns in a racially diverse population within an integrated health delivery system

    ✓ Peer-reviewed Health systems and care delivery Alzheimer s & Dementia

    Key finding: Nearly half of the incident ADRD codes were associated with a hospital‐based encounter. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-12-01

    Predictors of Disenrollment Among Medicare Fee-for-Service Beneficiaries With Dementia

    ✓ Peer-reviewed Health systems and care delivery Innovation in Aging

    Key finding: Medicare enrollment among people with Alzheimer’s Disease and Related Dementias (ADRD) has reached an all-time high with about 12% of beneficiaries having an ADRD diagnosis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2021-12-01

    Xenogeneic skin transplantation promotes angiogenesis and tissue regeneration through activated Trem2+ macrophages

    ✓ Peer-reviewed TREM2 and immune genetics Science advances

    Key finding: The relationship between the immune response to foreign grafts and their impact on wound healing has not been fully elucidated. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-12-01

    TREM2-independent oligodendrocyte, astrocyte, and T cell responses to tau and amyloid pathology in mouse models of Alzheimer disease

    ✓ Peer-reviewed TREM2 and immune genetics Cell reports

    Key finding: Here we utilize single-cell RNA sequencing to broadly profile 13 cell types in three different mouse models of Alzheimer disease (AD), capturing the effects of tau-only, amyloid-only, or combined tau-amyloid pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021-12-01

    AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation

    ✓ Peer-reviewed TREM2 and immune genetics Science translational medicine

    Key finding: Using transcriptomic analysis of single nuclei from brain tissues of patients with AD carrying the R47H mutation or the common variant (CV)– TREM2 , we found that R47H-associated microglial subpopulations had enhanced inflammatory signatures reminiscent of previously identified disease-associated microglia (DAM) and hyperactivation of AKT, one of the signaling pathways downstream of TREM2. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-12-01

    Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Brain : a journal of neurology

    Key finding: In particular, there is evidence supporting a critical role of astroglial activation and astrocytosis in Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2021-12-01

    Evidence and implications of abnormal predictive coding in dementia

    ✓ Peer-reviewed Digital health tools Brain : a journal of neurology

    Key finding: The diversity of cognitive deficits and neuropathological processes associated with dementias has encouraged divergence in pathophysiological explanations of disease.

    Full summary, score breakdown and related studies → Original source

  22. 2021-12-01

    Performance of Machine Learning Algorithms for Predicting Progression to Dementia in Memory Clinic Patients

    ✓ Peer-reviewed Digital health tools JAMA network open

    Key finding: These findings suggest that machine learning algorithms could accurately predict incident dementia within 2 years in patients receiving care at memory clinics using only 6 variables. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-12-01

    Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: This study suggests that plasma GFAP is a sensitive biomarker for detecting and tracking reactive astrogliosis and Aβ pathology even among individuals in the early stages of AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

November 2021 2

  1. 2021-11-30

    The Neutrophil to Lymphocyte Ratio Is Associated With the Risk of Subsequent Dementia in the Framingham Heart Study

    ✓ Peer-reviewed Long-term cohort studies Frontiers in aging neuroscience

    Key finding: The objective of this study was to investigate whether increased NLR in older adults is independently associated with the risk of subsequent dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-11-29

    Abundance of Nef and p-Tau217 in Brains of Individuals Diagnosed with HIV-Associated Neurocognitive Disorders Correlate with Disease Severance

    ✓ Peer-reviewed Biomarkers Molecular Neurobiology

    Key finding: The pathogenic mechanisms of HAND and of its connection to HIV infection remain unknown, but one of the considered hypotheses suggests that HIV infection accelerates the development of Alzheimer’s disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →