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Predictors of same-admission cholecystectomy in mild, acute, biliary pancreatitis
Shmelev Artem, Axentiev Anna, Hossain Mian B, Cunningham Steven C. HPB : the official journal of the International Hepato Pancreato Biliary Association, 2021-06-09
Topic: Amyloid, tau and blood-test diagnosis
Failure to perform same-admission cholecystectomy (SA-CCY) for mild, acute, biliary pancreatitis (MABP) is a recognized risk factor for recurrence and readmission. However, rates of SA-CCY are low and factors associated with these low rates require elucidation. Primary MAPB admissions were pooled from NIS 2000-2014 (weighted n = 578 258). Patients with chronic pancreatitis, pancreatic masses, alcohol-related disorders, hypertriglyceridemia, acute cholecystitis and AP-related organ dysfunction or complications were excluded. Annual rates of SA-CCY were calculated. Regression model for prediction of SA-CCY was built on 2010-2011 subset (weighted n = 74 169), yielding 96.3% of complete observations. Nationwide rate of SA-CCY in the U.S. was 40.8%. In multivariate analysis, SA-CCY was positively associated with BMI>30 (OR = 1.4, 95%CI 1.2-1.6), Asian ethnicity (vs. Black; OR = 1.2, 95%CI 1.0-1.5), private insurance (vs. Medicare; OR = 1.1, 95%CI 1.0-1.3), large (vs. small; OR = 1.3, 95%CI 1.2-1.4) urban hospitals (vs. rural; OR = 1.5 95%CI 1.3-1.7) of the South (vs. Northeast; OR = 1.5, 95%CI 1.3-1.7), as well as with chronic cholecystitis (OR = 17.0, 95%CI 15.4-18.7) and abdominal-wall hernias (OR = 5.2; 95%CI 3.0-8.9); the latter two predictors were not included in the final model. SA-CCY was negatively associated with age >40 (OR = 0.72; 95%CI 0.66-0.79), male gender (OR = 0.86, 95%CI 0.80-0.93), dementia (OR = 0.88, 95%CI 0.72-1.1), chronic comorbidities (OR = 0.64; 95%CI 0.54-0.77) and ostomies (OR = 0.51; 95%CI 0.31-0.86). Adherence to SA-CCY guidelines for MABP remains inadequate. Independent geographic variation in SA-CCY rates may be related to reimbursement differences, ownership of AP patients, accessibility to surgical care, or cultural characteristics of the patient population.
Key findings
- However, rates of SA-CCY are low and factors associated with these low rates require elucidation.
- In multivariate analysis, SA-CCY was positively associated with BMI>30 (OR = 1.4, 95%CI 1.2-1.6), Asian ethnicity (vs.
- SA-CCY was negatively associated with age >40 (OR = 0.72; 95%CI 0.66-0.79), male gender (OR = 0.86, 95%CI 0.80-0.93), dementia (OR = 0.88, 95%CI 0.72-1.1), chronic comorbidities (OR = 0.64; 95%CI 0.54-0.77) and ostomies (OR = 0.51; 95%CI 0.31-0.86).
Why it matters
This study of mild, acute, biliary pancreatitis found that dementia was among the factors negatively associated with same-admission cholecystectomy. It is about surgical care decisions in pancreatitis, not about treating, curing, or preventing Alzheimer's disease.
Study details
- Participants578
- Effect size96.3%; 40.8%; OR = 1.4
- Evidence strengthLow
How this study scored 37/100
Published in a peer-reviewed journal. Scored zero for study design and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (HPB : the official journal of the International Hepato Pancreato Biliary Association) |
| Journal's citation record | 1 / 4 | HPB: journal h-index 116 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 3 / 5 | 2021 — within 6 year(s) of the newest study here |
| Sample size | 2 / 4 | 578 participants |
| Effect reported | 3 / 3 | Effect reported with a statistic (interval, p-value, ratio or similar) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 4 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.6 citations a year over 7 year(s) since 2021 |
| Impact for its field and year | 1 / 6 | Cited 0.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 2 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Steven Clark Cunningham: h-index 33 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | Morgan State University: institution h-index 204 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 34099373) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 37 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
APA 7th
Artem, S., Anna, A., Hossain Mian, B., & Cunningham Steven, C. (2021). Predictors of same-admission cholecystectomy in mild, acute, biliary pancreatitis. HPB : the official journal of the International Hepato Pancreato Biliary Association. https://doi.org/10.1016/j.hpb.2021.04.002
Vancouver
Artem S, Anna A, Hossain Mian B, Cunningham Steven C. Predictors of same-admission cholecystectomy in mild, acute, biliary pancreatitis. HPB : the official journal of the International Hepato Pancreato Biliary Association. 2021. doi:10.1016/j.hpb.2021.04.002. PMID: 34099373.
BibTeX
@article{artem2021-34099373,
author = {Artem, Shmelev and Anna, Axentiev and Hossain Mian, B. and Cunningham Steven, C.},
title = {{Predictors of same-admission cholecystectomy in mild, acute, biliary pancreatitis}},
journal = {HPB : the official journal of the International Hepato Pancreato Biliary Association},
year = {2021},
doi = {10.1016/j.hpb.2021.04.002},
pmid = {34099373},
url = {https://doi.org/10.1016/j.hpb.2021.04.002}
}
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