Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 2,801–2,825 of 27,380 studies, newest first · page 113 of 1096.
October 2025 25
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2025-10-31
Roles of TREM2 in Alzheimer's disease
43/100 ✓ Peer-reviewed TREM2 and immune genetics Translational neurodegeneration
Key finding: Variants in the triggering receptor expressed on myeloid cells 2 (TREM2) gene have been demonstrated to increase the risk of late-onset Alzheimer's disease (AD) and Nasu-Hakola disease.
Full summary, score breakdown and related studies → Original source
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2025-10-31
A Cohort Study on Alzheimer's Disease in Relation to Residential Magnetic Fields From Indoor Transformer Stations
59/100 ✓ Peer-reviewed Health systems and care delivery Bioelectromagnetics
Key finding: Meta-analyses of epidemiological studies have suggested that Alzheimer's disease (AD) may be linked with exposure to extremely low frequency (ELF) magnetic fields (MF). +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-31
GUIDE and Beyond: Strategies for Comprehensive Dementia Care Integration
39/100 ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society
Key finding: Drawing from the experiences of six previously tested programs-Aging Brain Care, Alzheimer's and Dementia Care, BRI Care Consultation, Care Ecosystem, Integrated Memory Care, and MIND at Home-we describe a four-step approach to enable successful adoption and implementation: identifying key leaders and partners, preparing a tailored value proposition, initiating program start-up, and ensuring sustainable implementation. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-31
Behavioral Challenges and Adaptive Strategies in Providing Mealtime Care to Residents With Dementia: A Qualitative Study of Nursing Home Clinical and Administrative Staff
35/100 ✓ Peer-reviewed Clinical safety Journal of Applied Gerontology
Key finding: This study examined how nursing home staff adapt to challenging mealtime behaviors in residents with dementia, such as turning away or refusing food.
Full summary, score breakdown and related studies → Original source
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2025-10-31
Direct and indirect role of non-coding RNAs in company with amyloid and tau protein in promoting neuroinflammation in post-ischemic brain neurodegeneration
36/100 ✓ Peer-reviewed Inflammation and the immune system Frontiers in Cellular Neuroscience
Key finding: In particular, it clarifies whether the cooperation of non-coding RNAs with amyloid and tau protein enhances neuroinflammation and whether the vicious cycle of neuroinflammatory responses affects the production, behavior, and aggregation of these molecules. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-31
Astrocytes and Microglia in Alzheimer's Disease: Friends, Foes, or Both?
38/100 ✓ Peer-reviewed Inflammation and the immune system Developmental Neurobiology
Key finding: Microglia, the resident immune cells of the central nervous system, and astrocytes, key regulators of homeostasis and neurotransmission, undergo significant phenotypic changes in response to AD pathology.
Full summary, score breakdown and related studies → Original source
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2025-10-31
Alzheimer Syndrome or Age-Related Dementia—History, Therapy and Prevention
35/100 ✓ Peer-reviewed Brain tissue and pathology Journal of Clinical Medicine
Key finding: This new nosology has been widely criticized, given the absence of curative therapy, the evidence of mixed pathology in most cases and the decline in the dementia/AD incidence in high-income countries. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-31
Identifying potential drug targets for cerebral amyloid angiopathy: A Mendelian randomization study based on the druggable genes
33/100 ✓ Peer-reviewed Brain tissue and pathology Medicine
Key finding: Cis-expression quantitative trait locus (cis-eQTL) of druggable genes from eQTLGen Consortium and genome-wide association study of CAA from FinnGen database were used to screen for drug-usable genes causally associated with CAA. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-31
TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD
52/100 ✓ Peer-reviewed Brain tissue and pathology Nature Neuroscience
Key finding: Using iPSC-derived neurons and postmortem ALS/FTD brain and spinal cord tissue we find widespread, disease-specific and TDP-43-specific skipping of an exon encoding the KCNQ2 pore domain. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-31
Examining neuropsychiatric symptoms and functional decline in behavioral variant frontotemporal dementia
43/100 ✓ Peer-reviewed Lewy body dementia International Review of Psychiatry
Key finding: Impairments in transactions (47%) and verbal communication (44%) were common at baseline, while impairments in self-care and incontinence ( 40%). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-31
Lecanemab, Donanemab, and Emerging Disease Modifying Therapies for Alzheimer Disease: Clinical Evidence and Primary Care Implications in Canada
31/100 ✓ Peer-reviewed Treatments International Journal of Science and Research Archive
Key finding: Monoclonal antibodies such as lecanemab and donanemab show reduction in amyloid plaque and slowing of cognitive and functional decline (modest) in early AD (mild cognitive impairment or mild dementia). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-31
Lecanemab, Donanemab, and Emerging Disease Modifying Therapies for Alzheimer Disease: Clinical Evidence and Primary Care Implications in Canada
45/100 ✓ Peer-reviewed Treatments International Journal of Science and Research Archive
Key finding: Monoclonal antibodies such as lecanemab and donanemab show reduction in amyloid plaque and slowing of cognitive and functional decline (modest) in early AD (mild cognitive impairment or mild dementia). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-31
Lecanemab, Donanemab, and Emerging Disease Modifying Therapies for Alzheimer Disease: Clinical Evidence and Primary Care Implications in Canada
31/100 ✓ Peer-reviewed Treatments International Journal of Science and Research Archive
Key finding: Monoclonal antibodies such as lecanemab and donanemab show reduction in amyloid plaque and slowing of cognitive and functional decline (modest) in early AD (mild cognitive impairment or mild dementia). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-30
Alpha-synuclein deposition patterns in Alzheimer's disease: association with cortical amyloid beta and variable tau load
46/100 ✓ Peer-reviewed Brain tissue and pathology Acta neuropathologica
Key finding: Relationships with age, sex, and ApoE genotype were examined. α-syn co-pathology was detected in 60% of AD cases, more frequently, although not significantly, in women. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-30
Exercise and the blood-brain barrier: Mechanistic insights and therapeutic implications
43/100 ✓ Peer-reviewed Prevention trials Neurobiology of disease
Key finding: In recent years, exercise, as a low-cost and low-side-effect non-pharmacological intervention, has demonstrated significant potential in modulating the structure and function of the BBB. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-10-30
Performance of blood biomarkers in internal jugular vein for Alzheimer's disease pathologies: the Delta Method study
59/100 ✓ Peer-reviewed Biomarkers Science bulletin
Key finding: The results showed that the levels of Aβ42, Aβ40, p-tau217, p-tau181, GFAP, and NfL were higher in the IJV than in MCV and were highly correlated between the two sites. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-30
Association between different dietary patterns and the risk of major brain disorders: a prospective multi-cohort study
58/100 ✓ Peer-reviewed Prevention trials EClinicalMedicine
Key finding: In the UK Biobank cohort (N = 166,916), MIND diet demonstrated the broadest neuroprotective effects. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-30
The brain neurovascular epigenome and its association with dementia
45/100 ✓ Peer-reviewed Inflammation and the immune system Neuron
Key finding: Cerebral small vessel disease (SVD) is frequently comorbid with Alzheimer's disease (AD), and brain endothelial cells (BECs) express genes associated with AD genetic risk. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-30
Psychological distress and cultural role conflict among dementia family caregivers in China: a phenomenological study
41/100 ✓ Peer-reviewed Caregiving BMC Nursing
Key finding: Four themes emerged: layered caregiving burden, cultural strain and emotional dissonance, dual emotional experiences of caregiving, and coping strategies and unmet needs. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-30
rs140926439 Variant in the Fibronectin FN1 Gene Lowers Risk of Alzheimer Disease in APOEε4 Carriers in the UK Biobank Cohort
31/100 ✓ Peer-reviewed Genetics Alzheimer Disease & Associated Disorders
Key finding: When rs140926439 was absent, 0.10% of APOEε2/3 carriers had AD, while 0.43% of APOEε4 carriers or homozygotes had AD. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-30
Impact of preanalytical delay on the performance of plasma Aβ42, Aβ42/40, p‐tau217, and p‐tau217/Aβ42 in detecting brain amyloidosis in the ALZAN cohort
52/100 ✓ Peer-reviewed Biomarkers Alzheimer s & Dementia
Key finding: The preanalytical delay has a significant impact for Aβ40 and Aβ42. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-30
Association between vaccinations and risk of dementia: a systematic review and meta-analysis
69/100 ✓ Peer-reviewed Prevention and risk Age and Ageing
Key finding: Adult vaccinations, particularly against herpes zoster, influenza, pneumococcus and Tdap, are associated with a lower risk of dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-29
A randomized clinical trial of low-dose cannabis extract in Alzheimer's disease
79/100 ✓ Peer-reviewed Clinical trials Journal of Alzheimer's disease : JAD
Key finding: BackgroundPreclinical and clinical evidence suggest that low-dose cannabinoids could ameliorate Alzheimer's disease (AD) signs and symptoms. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-29
Effect of Intensive Systolic Blood Pressure Control on Markers of Cerebral Small Vessel Disease by Age
53/100 ✓ Peer-reviewed Vascular contributions Hypertension
Key finding: In SPRINT, the overall interaction between age and SBP on WMHv change was not statistically significant ( P =0.18). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-29
Neuropathologic Changes in People With Essential Tremor With Dementia
58/100 ✓ Peer-reviewed Disease mechanisms Neurology
Key finding: Other neuropathologies were similar across cognitive groups. +3 more findings
Full summary, score breakdown and related studies → Original source
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