Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 2,926–2,950 of 27,380 studies, newest first · page 118 of 1096.
October 2025 25
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2025-10-15
A Qualitative Study to Characterize the Experiences of Patients and Caregivers With Dementia Diagnostic Disclosure Communication and Care Planning
41/100 ✓ Peer-reviewed Caregiving Journal of Geriatric Psychiatry and Neurology
Key finding: First, perceptions of respectful or disrespectful communication affect the relationship with clinicians and contributes to positive or negative communication experiences. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-15
Avanços na doença de Alzheimer: diagnóstico precoce, biomarcadores e perspectivas futuras
26/100 ✓ Peer-reviewed Treatments BioSCIENCE
Key finding: A estrutura ATN categoriza a progressão da doença, integrando marcadores neurodegenerativos e inflamatórios. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-15
Associations of place‐based social determinants of health with biomarkers of Alzheimer's disease and related dementias
44/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia Behavior & Socioeconomics of Aging
Key finding: Place-based SDoH measures were higher in Black compared to White participants. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-14
Genetic and proteomic analysis identifies BAG3 as an amyloid-responsive regulator of neuronal proteostasis
46/100 ✓ Peer-reviewed Disease mechanisms Acta neuropathologica
Key finding: Across this panel of neurons, we observed substantial inter-individual differences in autophagic flux, which was inversely correlated with UPS activity. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-14
Plasma NfL and cognitive functioning in older adults: The moderating role of HDL cholesterol
55/100 ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)
Key finding: Significant interaction effects were observed: MoCA (β = -1.86×10-4, P = 0.006) and PACC (β = -4.0×10-5, P = 0.004), indicating HDL moderates the negative association between NfL and cognition. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-14
Social isolation and cognitive decline in older adults: a longitudinal study across 24 countries
65/100 ✓ Peer-reviewed Risk factors BMC Geriatrics
Key finding: Social isolation was significantly associated with reduced cognitive ability (pooled effect = -0.07, 95% CI = -0.08, -0.05), with consistently negative effects across memory, orientation, and executive ability. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-14
Urban Planning for Disaster Risk Reduction and Climate Change Adaptation: A Review at the Crossroads of Research and Practice
41/100 ✓ Peer-reviewed Prevention and risk Sustainability
Key finding: To navigate this vast body of knowledge, a conceptual framework is proposed to guide the selection of the relevant literature, and the strategy for this selection is detailed in the methodological section. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-14
Utilization of home- and community-based services among rural family caregivers of persons with dementia: the role of the area deprivation index
40/100 ✓ Peer-reviewed Risk factors Frontiers in Public Health
Key finding: About 65% of caregivers used at least one support service, with 52% utilizing home-based services and 52% community-based services. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-14
Cerebrospinal Fluid Biomarkers Profiling in Cerebral Amyloid Angiopathy and Relationship With Disease Phenotypes
44/100 ✓ Peer-reviewed Tau biomarkers Journal of the American Heart Association
Key finding: Cerebral amyloid angiopathy (CAA) is a heterogeneous small vessel disease that can occur independently or alongside Alzheimer disease (AD). +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-14
Prioritizing Modifiable Risk Factors for Dementia Prevention across the Spectrum of Genetic Susceptibility: A Prospective Cohort Study
58/100 ✓ Peer-reviewed Genetics Annals of Neurology
Key finding: Our findings highlight the importance of personalized risk assessments and the development of tailored interventions based on genetic background to prevent dementia more effectively. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-14
Culturally sensitive CLEAR guidelines on disclosing and communicating a diagnosis of dementia
50/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer's & Dementia
Key finding: HIGHLIGHTS: Healthcare practitioners (HCPs) struggle with disclosing and communicating dementia diagnoses. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-14
A randomized trial of two online platforms for dementia family caregivers: GamePlan4Care and Resources4Care
59/100 ✓ Peer-reviewed Caregiving Alzheimer's & Dementia
Key finding: Improving digital technology for caregivers requires studies with larger populations and longitudinal outcomes.
Full summary, score breakdown and related studies → Original source
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2025-10-13
Microbiota-gut-brain axis dysregulation in Alzheimer's disease and its modulation through probiotic supplementation
45/100 ✓ Peer-reviewed Disease mechanisms Brain, behavior, and immunity
Key finding: pAD patients showed intestinal inflammation, an altered GM profile, blood changes in the tryptophan metabolism, and reduced glutamate levels compared with HC (p-value < 0.049). +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-13
Phosphodiesterase-5 Inhibition and Alzheimer's Disease Risk: A Mendelian Randomisation Study
43/100 ✓ Peer-reviewed Genetics Aging cell
Key finding: While preclinical studies suggest that Phosphodiesterase 5 (PDE5) inhibition may reduce cognitive impairment, findings from observational studies on whether PDE5 inhibitors reduce Alzheimer's disease (AD) risk have been inconsistent. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-10-13
Smartphone use by people with dementia: An exploratory survey
59/100 ✓ Peer-reviewed Cognitive tests and assessment Maturitas
Key finding: There were 719 respondents (276 people with dementia, 443 carers). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-13
Impact of Specialty and Nonspecialty Palliative Care on Quality of Dying With Alzheimer's Disease or Related Dementias
61/100 ✓ Peer-reviewed End-of-life care Medical Care
Key finding: Nineteen articles involving 142,772 participants were included. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-13
Effects of Computerized Cognitive Training on Vesicular Acetylcholine Transporter Levels using [18F]Fluoroethoxybenzovesamicol Positron Emission Tomography in Healthy Older Adults: Results from the Improving Neurological Health in Aging via Neuroplasticity-based Computerized Exercise (INHANCE) Randomized Clinical Trial
54/100 ✓ Peer-reviewed Prevention trials JMIR Serious Games
Key finding: Among the 92 participants in the ITT population (mean age 71.9 years; mean education 16.5 years; 61/92, 66%, women; 88/92, 96%, White), 82 (89%) completed all study activities. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-13
Glycemic index, glycemic load, and risk of dementia: a prospective analysis within the UK Biobank cohort
38/100 ✓ Peer-reviewed Long-term cohort studies International Journal of Epidemiology
Key finding: Dementia incidence was 0.89 per 1000 person-years. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-13
A radiomics model predicts progression from mild cognitive impairment to alzheimer’s disease using structural MRI
43/100 ✓ Peer-reviewed Mild cognitive impairment Scientific Reports
Key finding: Stepwise logistic regression analysis showed that clinical dementia rating (CDR), Alzheimer's Disease Assessment Scale (ADAS-cog) and radiomics markers were independent predictors of progression from MCI to AD. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-13
Sleep disorders and the risk of cognitive decline or dementia: an updated systematic review and meta-analysis of longitudinal studies
62/100 ✓ Peer-reviewed Prevention and risk Journal of Neurology
Key finding: This meta-analysis highlights sleep management as a pivotal modifiable factor in reducing the risk of all-cause cognitive decline. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-12
Air toxics and late-life dementia and cognitive impairment in Mexican Americans
54/100 ✓ Peer-reviewed Risk factors Environmental research
Key finding: Among the air toxics, higher 1,3-butadiene levels we estimated a hazard ratio of 1.12 (95 % CI: 1.00, 1.25) for incident dementia/CIND per IQR increase in 1,3-butadiene exposures. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-12
Midbrain degeneration triggers astrocyte reactivity and tau pathology in experimental Alzheimer’s Disease
43/100 ✓ Peer-reviewed Inflammation and the immune system Molecular Neurodegeneration
Key finding: The concomitant depletion of dopaminergic and serotonergic inputs within the hippocampus of C57BL/6N mice provokes a pronounced activation of microglia via the NLRP3-inflammasome pathway, accompanied by increased IL-1β expression. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-11
Microbiota-gut-brain axis and probiotics: potential therapeutic strategies for treating Alzheimer's disease
61/100 ✓ Peer-reviewed Disease mechanisms Nutritional neuroscience
Key finding: Compared to healthy controls, mild cognitive impairment and AD were associated with low levels of Firmicutes and Bifidobacterium and high levels of Proteobacteria and Bacteroidetes.
Full summary, score breakdown and related studies → Original source
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2025-10-11
Efficacy of Mediterranean diet for the prevention of neurological diseases: A systematic review and meta-analysis featured in the Italian National Guidelines "La Dieta Mediterranea"
79/100 ✓ Peer-reviewed Prevention and risk Nutrition (Burbank, Los Angeles County, Calif.)
Key finding: Forty-five studies involving over 730 000 participants were included. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-10-11
Cognitive Outcomes After Hip Fracture Surgery: The Association of Postoperative Delirium on Previously Cognitively Normal Older Adults
49/100 ✓ Peer-reviewed Cognitive tests and assessment American Journal of Geriatric Psychiatry
Key finding: 36.5% of the overall cohort experienced delirium. +4 more findings
Full summary, score breakdown and related studies → Original source
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