Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
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  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 2,926–2,950 of 27,380 studies, newest first · page 118 of 1096.

October 2025 25

  1. 2025-10-15

    A Qualitative Study to Characterize the Experiences of Patients and Caregivers With Dementia Diagnostic Disclosure Communication and Care Planning

    ✓ Peer-reviewed Caregiving Journal of Geriatric Psychiatry and Neurology

    Key finding: First, perceptions of respectful or disrespectful communication affect the relationship with clinicians and contributes to positive or negative communication experiences. +4 more findings

  2. 2025-10-15

    Avanços na doença de Alzheimer: diagnóstico precoce, biomarcadores e perspectivas futuras

    ✓ Peer-reviewed Treatments BioSCIENCE

    Key finding: A estrutura ATN categoriza a progressão da doença, integrando marcadores neurodegenerativos e inflamatórios. +4 more findings

  3. 2025-10-15

    Associations of place‐based social determinants of health with biomarkers of Alzheimer's disease and related dementias

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia Behavior & Socioeconomics of Aging

    Key finding: Place-based SDoH measures were higher in Black compared to White participants. +2 more findings

  4. 2025-10-14

    Genetic and proteomic analysis identifies BAG3 as an amyloid-responsive regulator of neuronal proteostasis

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica

    Key finding: Across this panel of neurons, we observed substantial inter-individual differences in autophagic flux, which was inversely correlated with UPS activity. +3 more findings

  5. 2025-10-14

    Plasma NfL and cognitive functioning in older adults: The moderating role of HDL cholesterol

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Significant interaction effects were observed: MoCA (β = -1.86×10-4, P = 0.006) and PACC (β = -4.0×10-5, P = 0.004), indicating HDL moderates the negative association between NfL and cognition. +2 more findings

  6. 2025-10-14

    Social isolation and cognitive decline in older adults: a longitudinal study across 24 countries

    ✓ Peer-reviewed Risk factors BMC Geriatrics

    Key finding: Social isolation was significantly associated with reduced cognitive ability (pooled effect = -0.07, 95% CI = -0.08, -0.05), with consistently negative effects across memory, orientation, and executive ability. +3 more findings

  7. 2025-10-14

    Urban Planning for Disaster Risk Reduction and Climate Change Adaptation: A Review at the Crossroads of Research and Practice

    ✓ Peer-reviewed Prevention and risk Sustainability

    Key finding: To navigate this vast body of knowledge, a conceptual framework is proposed to guide the selection of the relevant literature, and the strategy for this selection is detailed in the methodological section. +4 more findings

  8. 2025-10-14

    Utilization of home- and community-based services among rural family caregivers of persons with dementia: the role of the area deprivation index

    ✓ Peer-reviewed Risk factors Frontiers in Public Health

    Key finding: About 65% of caregivers used at least one support service, with 52% utilizing home-based services and 52% community-based services. +4 more findings

  9. 2025-10-14

    Cerebrospinal Fluid Biomarkers Profiling in Cerebral Amyloid Angiopathy and Relationship With Disease Phenotypes

    ✓ Peer-reviewed Tau biomarkers Journal of the American Heart Association

    Key finding: Cerebral amyloid angiopathy (CAA) is a heterogeneous small vessel disease that can occur independently or alongside Alzheimer disease (AD). +3 more findings

  10. 2025-10-14

    Prioritizing Modifiable Risk Factors for Dementia Prevention across the Spectrum of Genetic Susceptibility: A Prospective Cohort Study

    ✓ Peer-reviewed Genetics Annals of Neurology

    Key finding: Our findings highlight the importance of personalized risk assessments and the development of tailored interventions based on genetic background to prevent dementia more effectively. +4 more findings

  11. 2025-10-14

    Culturally sensitive CLEAR guidelines on disclosing and communicating a diagnosis of dementia

    ✓ Peer-reviewed Getting a diagnosis Alzheimer's & Dementia

    Key finding: HIGHLIGHTS: Healthcare practitioners (HCPs) struggle with disclosing and communicating dementia diagnoses. +4 more findings

  12. 2025-10-14

    A randomized trial of two online platforms for dementia family caregivers: GamePlan4Care and Resources4Care

    ✓ Peer-reviewed Caregiving Alzheimer's & Dementia

    Key finding: Improving digital technology for caregivers requires studies with larger populations and longitudinal outcomes.

  13. 2025-10-13

    Microbiota-gut-brain axis dysregulation in Alzheimer's disease and its modulation through probiotic supplementation

    ✓ Peer-reviewed Disease mechanisms Brain, behavior, and immunity

    Key finding: pAD patients showed intestinal inflammation, an altered GM profile, blood changes in the tryptophan metabolism, and reduced glutamate levels compared with HC (p-value < 0.049). +3 more findings

  14. 2025-10-13

    Phosphodiesterase-5 Inhibition and Alzheimer's Disease Risk: A Mendelian Randomisation Study

    ✓ Peer-reviewed Genetics Aging cell

    Key finding: While preclinical studies suggest that Phosphodiesterase 5 (PDE5) inhibition may reduce cognitive impairment, findings from observational studies on whether PDE5 inhibitors reduce Alzheimer's disease (AD) risk have been inconsistent. +1 more finding

  15. 2025-10-13
  16. 2025-10-13
  17. 2025-10-13
  18. 2025-10-13
  19. 2025-10-13

    A radiomics model predicts progression from mild cognitive impairment to alzheimer’s disease using structural MRI

    ✓ Peer-reviewed Mild cognitive impairment Scientific Reports

    Key finding: Stepwise logistic regression analysis showed that clinical dementia rating (CDR), Alzheimer's Disease Assessment Scale (ADAS-cog) and radiomics markers were independent predictors of progression from MCI to AD. +2 more findings

  20. 2025-10-13

    Sleep disorders and the risk of cognitive decline or dementia: an updated systematic review and meta-analysis of longitudinal studies

    ✓ Peer-reviewed Prevention and risk Journal of Neurology

    Key finding: This meta-analysis highlights sleep management as a pivotal modifiable factor in reducing the risk of all-cause cognitive decline. +4 more findings

  21. 2025-10-12

    Air toxics and late-life dementia and cognitive impairment in Mexican Americans

    ✓ Peer-reviewed Risk factors Environmental research

    Key finding: Among the air toxics, higher 1,3-butadiene levels we estimated a hazard ratio of 1.12 (95 % CI: 1.00, 1.25) for incident dementia/CIND per IQR increase in 1,3-butadiene exposures. +4 more findings

  22. 2025-10-12

    Midbrain degeneration triggers astrocyte reactivity and tau pathology in experimental Alzheimer’s Disease

    ✓ Peer-reviewed Inflammation and the immune system Molecular Neurodegeneration

    Key finding: The concomitant depletion of dopaminergic and serotonergic inputs within the hippocampus of C57BL/6N mice provokes a pronounced activation of microglia via the NLRP3-inflammasome pathway, accompanied by increased IL-1β expression. +4 more findings

  23. 2025-10-11

    Microbiota-gut-brain axis and probiotics: potential therapeutic strategies for treating Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Nutritional neuroscience

    Key finding: Compared to healthy controls, mild cognitive impairment and AD were associated with low levels of Firmicutes and Bifidobacterium and high levels of Proteobacteria and Bacteroidetes.

  24. 2025-10-11
  25. 2025-10-11

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