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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 26,726–26,750 of 27,380 studies, newest first · page 1070 of 1096.

November 1993 13

  1. 1993-11-01

    Re-evaluation of the structural organization of neuritic plaques in Alzheimer's disease

    ✓ Peer-reviewed Drug development Journal of neuropathology and experimental neurology

    Key finding: Analysis of serial optical sections of neuritic plaques double-immunolabeled for anti-beta-amyloid/anti-tau-2 revealed that 35% of this type of plaque contained a dense amyloid core with clusters of peripheral abnormal neurites. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1993-11-01

    Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease

    ✓ Peer-reviewed Biomarkers The Journal of biological chemistry

    Key finding: Immunochemical and morphological analysis of AD P-tau preparations revealed that most of the protein was of non-PHF origin. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 1993-11-01

    X-chromosome effects on female brain: a magnetic resonance imaging study of Turner's syndrome

    ✓ Peer-reviewed Hippocampus size on brain scans Lancet (London, England)

    Key finding: The TS group had significantly lower scores than the controls for all the Wechsler adult intelligence scale tests, except verbal comprehension and reading level. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1993-11-01

    The Clinical Dementia Rating (CDR)

    ✓ Peer-reviewed Cognitive tests and assessment Neurology

    Full summary, score breakdown and related studies → Original source

  5. 1993-11-01

    The extent of phosphorylation of fetal tau is comparable to that of PHF-tau from Alzheimer paired helical filaments

    ✓ Peer-reviewed Drug development Brain research

    Key finding: The antibodies have been reported to recognize phosphate dependent epitopes at the carboxy-terminal half of the tau molecule. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1993-11-01

    Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia

    ✓ Peer-reviewed Risk genes beyond APOE Glia

    Key finding: In this disease complex amyloid-bearing neuritic plaques contain beta A4-amyloid protein, the APP, and numerous inflammatory proteins. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1993-11-01

    Morphological and biochemical analyses of amyloid plaque core proteins purified from Alzheimer disease brain tissue

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neurochemistry

    Key finding: Plaque core proteins were solubilized in formic acid which upon dialysis against guanidinium hydrochloride (GuHCl) partitioned into soluble (approximately 15%) and insoluble (approximately 85%) components. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1993-11-01

    Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Since A beta P-(1-40) comprises portions of the putative extracellular and membrane-spanning domains of the amyloid precursor protein (APP751), we suggested that the channel-forming property could be the underlying cause of amyloid neurotoxicity. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1993-11-01

    Platelet of Alzheimer patients: increased counts and subnormal uptake and accumulation of [14C]5-hydroxytryptamine

    ✓ Peer-reviewed Down syndrome and Alzheimer's Neuroscience letters

    Key finding: Our results indicate that in AD patients: (a) platelets are elevated, (b) their ability to accumulate 5-HT decreases and, (c) the kinetic parameters of 5-HT uptake are altered (decreased Km and Vmax), compared to non-demented healthy individuals. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 1993-11-01

    The apolipoprotein epsilon 4 allele in patients with Alzheimer's disease

    ✓ Peer-reviewed Disparities Annals of neurology

    Key finding: The epsilon 4 isoform of APO-E has been associated with both sporadic and familial late-onset AD, implying a causal role. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 1993-11-01

    Volumetric magnetic resonance imaging in men with dementia of the Alzheimer type: correlations with disease severity

    ✓ Peer-reviewed Brain scans and imaging Biological psychiatry

    Key finding: The whole group of DAT subjects had significantly smaller mean cerebral brain matter and temporal lobe volumes (p < 0.05), and significantly larger mean ventricular and temporal lobe peripheral CSF volumes than did controls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 1993-11-01

    Dementia in AIDS patients: incidence and risk factors. Multicenter AIDS Cohort Study

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: Overall, 15% of the cohort followed through death developed dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 1993-11-01

    L-deprenyl in the treatment of mild dementia of the Alzheimer type: results of a 15-month trial

    ✓ Peer-reviewed Treatments Journal of the American Geriatrics Society

    Key finding: L-deprenyl did appear to have a slight effect on a single measure of psychopathology, the BPRS. +1 more finding

    Full summary, score breakdown and related studies → Original source

October 1993 7

  1. 1993-10-01

    beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Trends in neurosciences

    Key finding: A major pathway of beta APP metabolism results in the release of secreted forms of beta APP, APPss.

    Full summary, score breakdown and related studies → Original source

  2. 1993-10-01

    Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions

    ✓ Peer-reviewed Genetics Neuron

    Key finding: 62% of patients with sporadic Alzheimer's disease possessed an ApoE-epsilon 4 allele, compared with 20% of controls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1993-10-01

    The clinical spectrum of cerebral amyloid angiopathy: presentations without lobar hemorrhage

    ✓ Peer-reviewed Brain tissue and pathology Neurology

    Key finding: We discuss seven patients with amyloid angiopathy presenting without major lobar hemorrhage. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1993-10-01

    Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: The more abundant APPs in the central nervous system are the 695-(APP695), 751- (APP751), and 770- (APP770) amino acid isoforms, and each could be the source of beta/A4 peptide that accumulates in the AD brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1993-10-01

    X-ray-induced chromatid damage in cells from Down syndrome and Alzheimer disease patients in relation to DNA repair and cancer proneness

    ✓ Peer-reviewed Down syndrome and Alzheimer's Cancer genetics and cytogenetics

    Key finding: This result indicates deficient repair of the DNA damage in DS cells. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1993-10-01

    Auditory function in Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Neurology

    Key finding: The pattern of cerebral degeneration in Alzheimer's disease (AD) patients suggests that basic auditory capacities should be normal in AD, whereas progressively higher levels of auditory function should be increasingly impaired. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1993-10-01

    Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

    ✓ Peer-reviewed Genetics Proceedings of the National Academy of Sciences of the United States of America

    Key finding: In an autopsy series of brains of late-onset AD patients, we found a strong association of APOE4 allele with increased vascular and plaque A beta deposits. +1 more finding

    Full summary, score breakdown and related studies → Original source

September 1993 5

  1. 1993-09-01

    Increased cytokine production in mononuclear cells of healthy elderly people

    ✓ Peer-reviewed Inflammation and the immune system European Journal of Immunology

    Key finding: Significant increases of IL-6, TNF-alpha and IL-1 beta levels were found in mitogen-stimulated cultures from aged donors, occurring at 24 to 72 h after stimulation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1993-09-01

    Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]

    ✓ Peer-reviewed Down syndrome and Alzheimer's Nature genetics

    Key finding: Overexpression of the gene encoding the beta-amyloid precursor protein (APP) may have a key role in the pathogenesis of both Alzheimer's disease (AD) and Down Syndrome (DS). +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1993-09-01

    Apolipoprotein E polymorphism and Alzheimer's disease

    ✓ Peer-reviewed Genetics Lancet (London, England)

    Key finding: Apolipoprotein E (apoE) is associated with Alzheimer's neurofibrillary tangles and beta-amyloid protein in senile plaques. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1993-09-01

    GFAP mRNA increases with age in rat and human brain

    ✓ Peer-reviewed Biomarkers Neurobiology of aging

    Key finding: GFAP mRNA increased in the hippocampus and striatum of 24 versus 6- to 7-month-old rats. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1993-09-01

    Temporal lobe regions on magnetic resonance imaging identify patients with early Alzheimer's disease

    ✓ Peer-reviewed Vascular contributions Archives of neurology

    Key finding: The results suggest that the hippocampus and the temporal horn of the lateral ventricles may be useful as antemortem markers of AD in mildly impaired patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →