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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 26,151–26,175 of 27,380 studies, newest first · page 1047 of 1096.

May 1997 15

  1. 1997-05-01

    Argyrophilic grain disease: widespread hyperphosphorylation of tau protein in limbic neurons

    ✓ Peer-reviewed Drug development Acta neuropathologica

    Key finding: These results demonstrate a widespread hyperphosphorylation of tau protein in the somatodendritic domain of neurons in AgD, in addition to silver grains in the neuropil. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1997-05-01

    Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

    ✓ Peer-reviewed Risk genes beyond APOE Nature

    Key finding: Approximately 10% of cases of Alzheimer's disease are familial and associated with autosomal dominant inheritance of mutations in genes encoding the amyloid precursor protein, presenilin 1 (PS1) and presenilin 2 (PS2). +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 1997-05-01

    Skeletal and CNS defects in Presenilin-1-deficient mice

    ✓ Peer-reviewed Risk genes beyond APOE Cell

    Key finding: These results show that PS1 is required for proper formation of the axial skeleton, normal neurogenesis, and neuronal survival.

    Full summary, score breakdown and related studies → Original source

  4. 1997-05-01

    Cortical and hippocampal volume deficits in temporal lobe epilepsy

    ✓ Peer-reviewed Hippocampus size on brain scans Epilepsia

    Key finding: Extrahippocampal volume abnormalities were bilateral and occurred in both temporal and extra-temporal cortical regions in TLE, whereas hippocampal deficits were related to the side of the epileptogenic focus. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 1997-05-01

    Atrial fibrillation and stroke prevention with warfarin in the long-term care setting

    ✓ Peer-reviewed Clinical safety Archives of internal medicine

    Key finding: Atrial fibrillation is common in patients residing in long-term care facilities, but its management with warfarin is highly variable. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1997-05-01

    Simulated car crashes and crash predictors in drivers with Alzheimer disease

    ✓ Peer-reviewed Clinical safety Archives of neurology

    Key finding: High-fidelity driving simulation provides a unique new source of performance parameters to standardize the assessment of driver fitness. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 1997-05-01

    Tumor necrosis factor-alpha, microglia and astrocytes in AIDS dementia complex

    ✓ Peer-reviewed Inflammation and the immune system Acta neuropathologica

    Key finding: They were compared with 6 control patients without neurological disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 1997-05-01

    Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease

    ✓ Peer-reviewed Inflammation and the immune system Proceedings of the National Academy of Sciences of the United States of America

    Key finding: We demonstrate that binding of amyloid-beta peptide (Abeta) to neuronal Receptor for Advanced Glycation Endproduct (RAGE), a cell surface receptor for Abeta, induces macrophage-colony stimulating factor (M-CSF) by an oxidant sensitive, nuclear factor kappaB-dependent pathway. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1997-05-01

    Insulin and cognitive function in an elderly population. The Rotterdam Study

    ✓ Peer-reviewed Long-term cohort studies Diabetes care

    Key finding: An increase in postload insulin only in women was associated with a decrease in cognitive function (age-adjusted regression coefficient -0.10 per 50 mU/l insulin; 95% CI -0.16 to -0.04). +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1997-05-01

    Rediscovery of the case described by Alois Alzheimer in 1911: historical, histological and molecular genetic analysis

    ✓ Peer-reviewed Risk genes beyond APOE Neurogenetics

    Key finding: Psych. 4: 356-385) on a peculiar case of the disease that had been named after him by Emil Kraepelin in 1910. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 1997-05-01

    Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein

    ✓ Peer-reviewed Risk genes beyond APOE Nature

    Key finding: Cleavage by as-yet unidentified proteases releases the beta-amyloid peptide in soluble form. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 1997-05-01

    Allelic variability in D21S11, but not in APP or APOE, is associated with cognitive decline in Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Neuroreport

    Key finding: Genetic variability at APOE and APP was not significantly associated with evidence of cognitive decline. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 1997-05-01

    Immunoreactivity of presenilin-1 in human, rat and mouse brain

    ✓ Peer-reviewed Down syndrome and Alzheimer's Brain research

    Key finding: Monoclonal antibodies (mAbs) D3G6 and C8A5, specific for amino acid residues 160-168 of S182 protein, immunolabeled neurons, ependymal and choroid plexus cells, and myocytes in brain sections from normal subjects and people with Alzheimer disease or Down syndrome and in rats and mice. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 1997-05-01

    The Neuropsychiatric Inventory: assessing psychopathology in dementia patients

    ✓ Peer-reviewed Caregiving Neurology

    Key finding: The NPI is sensitive to treatment effects and has demonstrated the amelioration of behavioral symptoms in Alzheimer's disease by cholinergic agents.

    Full summary, score breakdown and related studies → Original source

  15. 1997-05-01

    The epidemiology of estrogen replacement therapy and Alzheimer's disease

    ✓ Peer-reviewed Prevention and risk Neurology

    Key finding: Consistent with the estrogen hypothesis, cross-sectional studies imply that postmenopausal estrogen use could be associated with a lower risk for AD.

    Full summary, score breakdown and related studies → Original source

April 1997 10

  1. 1997-04-24

    A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study

    ✓ Peer-reviewed Clinical trials New England Journal of Medicine

    In patients with moderately severe impairment from Alzheimer's disease, treatment with selegiline or alpha-tocopherol slows the progression of disease.

    Full summary, score breakdown and related studies → Original source

  2. 1997-04-01

    Talking while walking: the effect of a dual task in aging and Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Neurology

    Key finding: The yOld and oOld did not differ from each other (p = 0.68). +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1997-04-01

    Widespread peroxynitrite-mediated damage in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Increasing evidence suggests that oxidative damage to proteins and other macromolecules is a salient feature of the pathology of Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1997-04-01

    Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing

    ✓ Peer-reviewed Drug development Genes and function

    Key finding: The conservation of function of human PS-1 and C. elegans sel-12 suggests that presenilin proteins are required, directly or indirectly, for the proper operation of the Notch signalling pathway.

    Full summary, score breakdown and related studies → Original source

  5. 1997-04-01

    Amyloid, the presenilins and Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Trends in neurosciences

    Key finding: It has also recently been shown that this form of A beta is deposited early and selectively in the disease process and is more fibrillogenic in vitro.

    Full summary, score breakdown and related studies → Original source

  6. 1997-04-01

    Dementia three months after stroke. Baseline frequency and effect of different definitions of dementia in the Helsinki Stroke Aging Memory Study (SAM) cohort

    ✓ Peer-reviewed Vascular contributions Stroke

    Key finding: We found that 451 (92.8%) of the patients were testable, 239 (49.2%) of the patients were women, and the mean age was 71.2 years. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1997-04-01

    Apolipoprotein E epsilon 4 allele and hippocampal volume in twins with normal cognition

    ✓ Peer-reviewed Hippocampus size on brain scans Neurology

    Key finding: There were no significant differences in neuropsychological measures of the groups categorized by the presence of an epsilon 4 allele. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1997-04-01

    [Health of Brazilian elderly just before of the 21st century: current problems, forecasts and alternatives]

    ✓ Peer-reviewed Clinical safety Revista de saude publica

    Key finding: Current characteristics and perspectives of Brazilian demographic and epidemiological transition processes are analyzed.

    Full summary, score breakdown and related studies → Original source

  9. 1997-04-01

    Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments

    ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences of the United States of America

    Key finding: There are no detectable deposits of beta-amyloid. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1997-04-01

    A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis

    ✓ Peer-reviewed Inflammation and the immune system Journal of immunology (Baltimore, Md. : 1950)

    Key finding: The strongest predictor for clinical dementia is the absolute numbers of immunocompetent brain macrophages. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →