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Home › Research › Topic

Brain imaging, connectivity and assessment

1,533 studies in this group. A computer grouped them by what their titles and summaries are about, not by a hand-made list. The name describes most of the group, not every study in it.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Pathways explaining racial/ethnic disparities in incident all-cause dementia among middle-aged US adults

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2023-03-03 Disparities

    Compared with Non-Hispanic White (NHW) adults, Non-White adults had a higher incidence of AD-specific (hazard ratio [HR] = 2.05, 95% confidence interval [CI]: 1.21, 3.49) and all-cause dementia (HR = 2.01, 95% CI: 1.36, 2.98).

  2. Unsupervised mobile app-based cognitive testing in a population-based study of older adults born 1944

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Frontiers in digital health 2022-11-08 Cognitive tests and assessment

    MDT-OS and ORR-LDR were weakly-to-moderately correlated with the Preclinical Alzheimer's Cognitive Composite (PACC5) (r = 0.3-0.44, p < .001) and with several other measures of episodic memory, processing speed, and executive function.

  3. Plasma neurofilament light as blood marker for poor brain white matter integrity among middle-aged urban adults

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Neurobiology of aging 2022-10-21 Biomarkers

    Plasma neurofilament light chain (NfL)'s link to dementia may be mediated through white matter integrity (WMI).

  4. Validation of the Remote Automated ki:e Speech Biomarker for Cognition in Mild Cognitive Impairment: Verification and Validation following DiME V3 Framework

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Digital biomarkers 2022-09-30 Cognitive tests and assessment

    Our results suggest that the ki:e SB-C is an objective, scalable, and reliable indicator of cognitive decline, fit for purpose as a remote assessment in clinical early dementia trials.

  5. Unsupervised high-frequency smartphone-based cognitive assessments are reliable, valid, and feasible in older adults at risk for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of the International Neuropsychological Society : JINS 2022-09-05 Cognitive tests and assessment

    Overall, the results suggest that ARC is reliable and valid and represents a feasible tool for assessing cognitive changes associated with the earliest stages of AD.

  6. Natural speech markers of Alzheimer's disease co-pathology in Lewy body dementias

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Parkinsonism & related disorders 2022-08-06 Brain tissue and pathology

    Age of acquisition of nouns (p = 0.034, |d| = 0.77) and lexical density (p = 0.0064, |d| = 0.72) were reduced in SYN + AD, and together showed excellent discrimination for SYN + AD vs. SYN-AD (95% sensitivity, 66% specificity; AUC = 0.82).

  7. Four Distinct Subtypes of Alzheimer's Disease Based on Resting-State Connectivity Biomarkers

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Biological psychiatry 2022-06-26 Brain scans and imaging

    Individuals with AD were clustered into 4 subtypes reproducibly, which included those with 1) diffuse and mild functional connectivity disruption (subtype 1), 2) predominantly decreased connectivity in the default mode network accompanied by an increase in the prefrontal circuit (subtype 2), 3) predominantly decreased connectivity in the anterior cingulate cortex accompanied by an increase in prefrontal cortex connectivity (subtype 3), and 4) predominantly decreased connectivity in the basal ganglia accompanied by an increase in prefrontal cortex connectivity (subtype 4).

  8. Metacognition, cortical thickness, and tauopathy in aging

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Neurobiology of aging 2022-06-25 Brain scans and imaging

    We investigated self-rating of cognitive task performance (self-appraisal) and the difference between self-rating and actual task performance (appraisal discrepancy) in cognitively healthy older adults and their relationship with cortical thickness and Alzheimer's disease (AD) biomarkers, amyloid and tau.

  9. Individualised computerised cognitive training for community-dwelling people with mild cognitive impairment: study protocol of a completely virtual, randomised, controlled trial

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Trials 2022-05-05 Cognitive tests and assessment

    This is the first study to investigate the effect of MAKSCog, an individualised CCT, specifically developed for people with different subtypes of MCI.

  10. A Computerized Cognitive Test Battery for Detection of Dementia and Mild Cognitive Impairment: Instrument Validation Study

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. JMIR aging 2022-04-15 Cognitive tests and assessment

    BrainCheck was able to distinguish between diagnoses of dementia, MCI, and NC, providing a potentially reliable tool for early detection of cognitive impairment.

  11. Crossed cerebellar diaschisis in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Nuclear medicine communications 2022-04-01 Drug development

    Comparison of SUVR in different brain regions demonstrated significant differences in the temporal, occipital and cerebellar cortices.

  12. Disrupted olfactory functional connectivity in patients with late-life depression

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of affective disorders 2022-03-13 Risk factors

    Compared with LLD patients without OI impairment and normal controls, LLD patients with OI impairment exhibited increased FC between the left orbital frontal cortex (OFC) and left calcarine gyrus, between the left OFC and right lingual gyrus, between the right OFC and right rectus gyrus, and decreased FC between the right piriform cortex and right superior parietal lobule.

  13. Differences in Odor Identification in Early-Onset and Late-Onset Depression

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Brain sciences 2022-02-16 Risk factors

    LOD patients exhibited lower OI scores than EOD patients and normal controls (NCs).

  14. Cognitive reserve as one of the determinants of the progression of Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Geriatrie et psychologie neuropsychiatrie du vieillissement 2022-01-12 Risk factors

    To assess the validity of Yaakov Stern's theory, which postulates that the first cognitive deficits of Alzheimer disease are delayed in patients with high cognitive reserve, compared to those with low cognitive reserve, but this is subsequently associated with faster cognitive decline when cerebral lesions have reached a certain degree of severity.

  15. Cognitive Reserve Modulates Brain Structure and Cortical Architecture in the Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of Alzheimer's disease : JAD 2022 Risk factors

    aMCI-HCR compared to aMCI-LCR patients showed significant decrease of CTh in the right temporal and in the left prefrontal lobe.

  16. Using Digital Speech Assessments to Detect Early Signs of Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Frontiers in digital health 2021-10-27 Cognitive tests and assessment

    Detecting early signs of cognitive decline is crucial for early detection and treatment of Alzheimer's Disease.

  17. Cognitive Reserve Characteristics and Occupational Performance Implications in People with Mild Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Healthcare (Basel, Switzerland) 2021-09-26 Risk factors

    The Cognitive Reserve hypothesis suggests that there are individual differences in the ability to cope with the pathologic changes in Alzheimer's Disease.

  18. Brain Network Integrity Changes in Subjective Cognitive Decline: A Possible Physiological Biomarker of Dementia

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Frontiers in neurology 2021-08-30 Cognitive tests and assessment

    Both DELPHI analysis of network function and DTI analysis detected a significant decrease in connectivity, excitability, and WM integrity in the SCD group compared to healthy control (HC) subjects; a significant decrease was also noted for aMCI and Dementia groups compared to HC.

  19. [Cognitive reserve, one of the determinants of the progression of Alzheimer's disease]

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Geriatrie et psychologie neuropsychiatrie du vieillissement 2021-06-01 Risk factors

    To appraise the validity of the Yaakov Stern's theory, which postulates that the first cognitive deficits of Alzheimer's disease are delayed in patients with high cognitive reserve, compared to those with low cognitive reserve, but is subsequently associated with faster cognitive decline when cerebral lesions have reached some degree of severity.

  20. Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Nature communications 2021-05-10 Down syndrome and Alzheimer's

    Synaptic disturbances in excitatory to inhibitory (E/I) balance in forebrain circuits are thought to contribute to the progression of Alzheimer's disease (AD) and dementia, although direct evidence for such imbalance in humans is lacking.

  21. Sleep Characteristics and Cognitive Function in Older Adults Without Dementia: The CABLE Study

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of Alzheimer's disease : JAD 2021 Tau biomarkers

    The Pittsburgh Sleep Quality Index (PSQI) total score was significantly negatively correlated with Montreal Cognitive Assessment (MoCA) score (p = 0.0176).

  22. Relationships Between Chronic Pain Stage, Cognition, Temporal Lobe Cortex, and Sociodemographic Variables

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of Alzheimer's disease : JAD 2021 Disparities

    There were ethnic/race group differences in MoCA scores but no relationships with chronic knee pain stage.

  23. A Validation Study of the Inbrain CST: a Tablet Computer-based Cognitive Screening Test for Elderly People with Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of Korean medical science 2020-08-31 Cognitive tests and assessment

    First, in the normative sample, the total score on the Inbrain CST was significantly affected by age, years of education, and gender.

  24. cCOG: A web-based cognitive test tool for detecting neurodegenerative disorders

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2020-08-25 Cognitive tests and assessment

    Web-based cognitive tests have potential for standardized screening in neurodegenerative disorders.

  25. Ethnoracial Differences in Lewy Body Diseases with Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of Alzheimer's disease : JAD 2020 Disparities

    Presentation age was similar between groups (median 74-75 years).

From across this topic

10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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